The presence of herpesviruses in malignant but not in benign or recurrent pleomorphic adenomas [0.03%]
存在于恶性但不存在于良性或复发性多形腺瘤中的疱疹病毒
Maria K Jauhiainen,Man Xu,Lari Pyöriä et al.
Maria K Jauhiainen et al.
Background: The etiology of salivary gland tumors is mainly unknown. The anatomical location of the salivary glands, with the mucosal pathway to the oral cavity and its rich microbiome, raises the question of potential vi...
Breast cancer suppression by curcumin-naringenin-magnetic-nano-particles: In vitro and in vivo studies [0.03%]
姜黄素-奈龄仁-磁纳米粒对乳腺癌的抑制作用：体内外研究
Mostafa A Askar,Omama E El Shawi,Omayma A R Abou Zaid et al.
Mostafa A Askar et al.
Background: The limitations of surgery, radiotherapy, and chemotherapy in cancer treatment and the increase in the application of nanomaterials in the field of biomedicine have promoted the use of nanomaterials in combina...
Early prediction of prostate cancer biochemical recurrence and identification of disease persistence using PSA isoforms and human kallikrein-2 [0.03%]
前列腺特异抗原同种型和人丝氨酸蛋白酶前体用于早期预测前列腺癌生化复发及判断疾病持续性
Joana Do Carmo Silva,Stepan Vesely,Hana Luksanova et al.
Joana Do Carmo Silva et al.
Background: The role of isoforms of prostate specific antigen (PSA) and other kallikrein-related markers in early detection of biochemical recurrence (BCR) after radical prostatectomy (RP) is not well known and serum PSA ...
The myeloid cell biomarker EMR1 is ectopically expressed in colon cancer [0.03%]
结肠癌中髓系细胞生物标志物EMR1的异位表达
Haytham Ali,Lina Olsson,Gudrun Lindmark et al.
Haytham Ali et al.
Objective: The microenvironment of colon cancer (CC) is heterogeneous including cells of myeloid lineage affecting tumor growth and metastasis. Two functional subtypes of myeloid cells have been identified; one (M1) is tu...
The secret identities of TMPRSS2: Fertility factor, virus trafficker, inflammation moderator, prostate protector and tumor suppressor [0.03%]
ACE2和TMPRSS2：SARS-CoV-2进入人体的“搭档”
Richard J Epstein
Richard J Epstein
The human TMPRSS2 gene is pathogenetically implicated in both coronaviral lung infection and prostate cancer, suggesting its potential as a drug target in both contexts. SARS-COV-2 spike polypeptides are primed by the host transmembrane TMP...
The expression of hACE2 receptor protein and its involvement in SARS-CoV-2 entry, pathogenesis, and its application as potential therapeutic target [0.03%]
hACE2受体蛋白的表达及其在SARS-CoV-2感染中的作用机制及作为潜在治疗靶点的应用价值
Lobna Al-Zaidan,Sarra Mestiri,Afsheen Raza et al.
Lobna Al-Zaidan et al.
Pneumonia cases of unknown etiology in Wuhan, Hubei province, China were reported to the World Health Organization on 31st of December 2019. Later the pathogen was reported to be a novel coronavirus designated severe acute respiratory syndr...
A review on the role of CAFs and CAF-derived exosomes in progression and metastasis of digestive system cancers [0.03%]
癌相关成纤维细胞及其衍生的外泌体在消化系统肿瘤进展和转移中的作用研究进展
Bahare Zarin,Laleh Rafiee,Parnaz Daneshpajouhnejad et al.
Bahare Zarin et al.
Cancers evolve as a result of the accelerated proliferation of cancer cells in a complicated, enriched, and active microenvironment. Tumor microenvironment (TME) components are the master regulators of any step of cancer development. The tu...
Angiogenesis' related genetic variants alter clinical features and prognosis of diffuse large B-cell lymphoma patients [0.03%]
血管生成相关遗传变异改变弥漫性大B细胞淋巴瘤患者的临床特征及预后
Angelo Borsarelli Carvalho Brito,Marcia Torresan Delamain,Marcello Ferreti Fanelli et al.
Angelo Borsarelli Carvalho Brito et al.
Objectives: Single nucleotide variants (SNVs) in vascular endothelial growth factor A (VEGFA) and VEGFA receptor (KDR) genes confer different inherited abilities in angiogenesis (AG) pathway. We aimed in the present study...
Validation of a clinical blood-based decision aid to guide immunotherapy treatment in patients with non-small cell lung cancer [0.03%]
非小细胞肺癌患者免疫治疗临床血液决策辅助工具的验证研究
Mirte Muller,Roland Hoogendoorn,Ruben J G Moritz et al.
Mirte Muller et al.
Background: The widespread introduction of immunotherapy in patients with advanced non-small cell lung cancer (NSCLC) has led to durable responses but still many patients fail and are treated beyond progression. ...
Lack of CD44 overexpression and application of concurrent chemoradiotherapy with cisplatin independently indicate excellent prognosis in patients with HPV-positive oropharyngeal cancer [0.03%]
CD44不表达及同期放化疗对HPV阳性口腔癌患者预后的影响
Beata Biesaga,M Kołodziej-Rzepa,A Janecka-Widła et al.
Beata Biesaga et al.
Background: HPV-16 positivity in patients with squamous cell carcinoma of oropharynx (OPSCC) is associated with better prognosis. However, in more than 40% of HPV infected patients progression of cancer disease is observe...