Computer-aided prognosis on breast cancer with hematoxylin and eosin histopathology images: A review [0.03%]
基于苏木精和伊红乳腺癌病理图像的计算机辅助预后研究：综述
Jia-Mei Chen,Yan Li,Jun Xu et al.
Jia-Mei Chen et al.
With the advance of digital pathology, image analysis has begun to show its advantages in information analysis of hematoxylin and eosin histopathology images. Generally, histological features in hematoxylin and eosin images are measured to ...
Impact of microRNA dynamics on cancer hallmarks: An oral cancer scenario [0.03%]
微RNA动力学对癌症标志物的影响——以口腔癌为例
V G Manasa,S Kannan
V G Manasa
MicroRNAs are endogenous small noncoding RNAs that negatively regulate gene expression at posttranscriptional level. The discovery of microRNAs has identified a new layer of gene regulation mechanisms, which play a pivotal role in developme...
The predicted target gene validation, function, and prognosis studies of miRNA-22 in colorectal cancer tissue [0.03%]
结直肠癌组织中miRNA-22的靶基因验证、功能及预后研究
Bo Li,Bai Li,Hongyan Sun et al.
Bo Li et al.
MicroRNAs are known as small, non-coding, and single-stranded RNAs which can regulate cell proliferation, differentiation, and apoptosis and involve in the development of tumors. In this study, colorectal cancer tissue morphological change ...
Specific tumor-derived CCL2 mediated by pyruvate kinase M2 in colorectal cancer cells contributes to macrophage recruitment in tumor microenvironment [0.03%]
结肠癌细胞中由丙酮酸激酶M2介导的特异性肿瘤衍生CCL2对肿瘤微环境中的巨噬细胞募集有贡献
Kejian Zou,Yaodong Wang,Yan Hu et al.
Kejian Zou et al.
Development of colorectal cancer has been considered as a result of imbalance of pro- and anti-inflammatory intestinal microenvironment accompanied by macrophage recruitment. Despite macrophages are implicated in remodeling tumor microenvir...
High mobility group box 1/toll-like receptor 4/myeloid differentiation factor 88 signaling promotes progression of gastric cancer [0.03%]
高迁移率族箱蛋白1/ Toll样受体4/髓系分化因子88信号促进胃癌进展
Yanqiu Yue,Tao Zhou,Yanjing Gao et al.
Yanqiu Yue et al.
High mobility group box 1 and toll-like receptor 4/myeloid differentiation factor 88 signaling pathway have been indicated to have oncogenic effects in many cancers. However, the role of high mobility group box 1/toll-like receptor 4/myeloi...
Selection of single chain antibody fragments binding to the extracellular domain of 4-1BB receptor by phage display technology [0.03%]
噬菌体展示技术筛选结合4-1BB受体胞外区的单链抗体片段
Salman Bagheri,Mehdi Yousefi,Elmira Safaie Qamsari et al.
Salman Bagheri et al.
The 4-1BB is a surface glycoprotein that pertains to the tumor necrosis factor-receptor family. There is compelling evidence suggesting important roles for 4-1BB in the immune response, including cell activation and proliferation and also c...
Clinical value of miR-145-5p in NSCLC and potential molecular mechanism exploration: A retrospective study based on GEO, qRT-PCR, and TCGA data [0.03%]
基于GEO、qRT-PCR和TCGA数据的miR-145-5p在NSCLC中的临床价值及潜在分子机制探讨：一项回顾性研究
Ting-Qing Gan,Zu-Cheng Xie,Rui-Xue Tang et al.
Ting-Qing Gan et al.
MicroRNAs have been reported to be involved in various biological processes. Here, we performed a systematic analysis to explore the clinical value and potential molecular mechanism of miR-145-5p in non-small cell lung cancer. First, a meta...
Ji Hae Nahm,Hye Min Kim,Ja Seung Koo
Ji Hae Nahm
We aimed to demonstrate the differences in the expression of glucose metabolism-related proteins according to the thyroid cancer subtypes and investigate the implications of these differences. A total of 566 thyroid cancer patients, includi...
Expression of RNA-binding motif 10 is associated with advanced tumor stage and malignant behaviors of lung adenocarcinoma cancer cells [0.03%]
RNA结合基序蛋白10的表达与肺腺癌细胞恶性进展相关
Guofang Guan,Ranwei Li,Wenfang Tang et al.
Guofang Guan et al.
This study assessed RNA-binding motif 10 expression in lung adenocarcinoma tissues and examined the role and mechanism of RNA-binding motif 10 in the regulation of lung adenocarcinoma malignancy. Lung adenocarcinoma and corresponding adjace...
Nuno Paula Santos,Aura Antunes Colaço,Paula Alexandra Oliveira
Nuno Paula Santos
Cancer is the first cause of death in developed countries and the second in developing countries. Concerning the most frequent worldwide-diagnosed cancer, primary liver cancer represents approximately 4% of all new cancer cases diagnosed gl...