Role of colony-stimulating factor 1 in the neoplastic process of tenosynovial giant cell tumor [0.03%]
集落刺激因子1在腱鞘巨细胞瘤肿瘤发生过程中的作用
William D Tap,John H Healey
William D Tap
Tenosynovial giant cell tumors (TGCTs) are rare, locally aggressive, mesenchymal neoplasms, most often arising from the synovium of joints, bursae, or tendon sheaths. Surgical resection is the first-line treatment, but recurrence is common,...
Jaume Trapé,Silvia Bérgamo,Laura González-Garcia et al.
Jaume Trapé et al.
From its onset and during its progression, lung cancer may affect various extrapulmonary structures. These include the serous membranes, the pleura and pericardium, and less frequently the central nervous system, with leptomeningeal involve...
ErbB4-encoded novel miRNAs act as tumor suppressors by regulating ErbB/PI3K signaling [0.03%]
ErbB4编码的新miRNA通过调节ErbB / PI3K信号传导而作为肿瘤抑制因子作用
Zahra Ghaemi,Bahram M Soltani,Seyed Javad Mowla
Zahra Ghaemi
Background: ErbB/PI3K signaling is widely recognized as a critical modulator of malignancy and miRNAs have been found to play a crucial role in the regulation of this pathway. ...
HE4 and CA125 serum biomarker monitoring in women with epithelial ovarian cancer [0.03%]
上皮性卵巢癌患者中HE4和CA125血清生物标记物的检测与监测
Alexandra Samborski,M Craig Miller,Alexandra Blackman et al.
Alexandra Samborski et al.
Background: CA125 is the gold standard serum biomarker for monitoring patients with epithelial ovarian cancer (EOC). Human epididymal protein 4 (HE4) is a novel serum biomarker for EOC patients. ...
Induction of alternative NF-κB within TAg-induced basal mammary tumors in activation-resistant inhibitor of κ-B kinase (IKKα) mutant mice [0.03%]
激活抵抗型抑制NF-κB的KB激酶(IKKα)突变小鼠中TAg诱导的基底乳腺肿瘤中可选择性活化NF-κB
Fares Ould-Brahim,Andrea Sau,David A Carr et al.
Fares Ould-Brahim et al.
Background: The alternative NF-κB pathway is activated by the NF-κB-inducing kinase (NIK) mediated phosphorylation of the inhibitor of κ-B kinase α (IKKα). IKKα then phosphorylates p100/NFKB2 to result in its proces...
Unfavorable prognosis and clinical consequences of APOBEC3B expression in breast and other cancers: A systematic review and meta-analysis [0.03%]
APOBEC3B表达对乳腺癌及其他癌症预后及临床结果的影响：系统性回顾和荟萃分析
Sima Jafarpour,Maryam Yazdi,Reza Nedaeinia et al.
Sima Jafarpour et al.
Introduction: Controversy exists regarding the association of apolipoprotein B mRNA editing enzyme catalytic subunit 3B APOBEC3B, (A3B) overexpression and poor prognosis, metastasis, and chemotherapy drug resistance in ca...