Serum MMP-8 and TIMP-1 as prognostic biomarkers in gastric cancer [0.03%]
血清MMP-8和TIMP-1作为胃癌预后生物标志物的研究
Alli Laitinen,Jaana Hagström,Harri Mustonen et al.
Alli Laitinen et al.
Despite gastric cancer being rare nowadays in Western countries, it remains one of the leading causes of cancer death worldwide. The course of the disease varies, so the individual gastric cancer patient's prognosis is difficult to determin...
Colon cancer-derived conditioned medium induces differentiation of THP-1 monocytes into a mixed population of M1/M2 cells [0.03%]
结肠癌细胞条件培养液诱导THP-1单核细胞分化成为M1/M2混合型肿瘤相关巨噬细胞
Katarzyna Sawa-Wejksza,Adrianna Dudek,Marta Lemieszek et al.
Katarzyna Sawa-Wejksza et al.
Macrophages play an important role in the immune response and in the maintenance of tissue homeostasis. It is well known that many tumors recruit monocytes from circulation and influence their differentiation, mainly into suppressive M2-lik...
Serum paraoxonase 1 activity and protein N-homocysteinylation in primary human endometrial cancer [0.03%]
人初级子宫内膜癌的血清胆碱酯酶1活性及蛋白N-同型半胱氨酸化作用
Krzysztof Gałczyński,Jerzy Bełtowski,Łukasz Nowakowski et al.
Krzysztof Gałczyński et al.
Paraoxonase 1 plays an important role in protection from oxidative stress and also decomposes homocysteine thiolactone, the toxic metabolite of homocysteine. A limited number of reports evaluated the role of paraoxonase 1 in women affected ...
Network analyses-based identification of circular ribonucleic acid-related pathways in intrahepatic cholangiocarcinoma [0.03%]
基于网络分析的肝内胆管癌环状RNA相关通路识别
Anuradha Moirangthem,Xue Wang,Irene K Yan et al.
Anuradha Moirangthem et al.
Circular ribonucleic acids are non-coding ribonucleic acids that can be identified from genome sequencing studies. Although they can be readily detected, their regulation and functional role in human diseases such as cancer are unknown. Usi...
TP53-dependence on the effect of doxorubicin and Src inhibitor combination therapy [0.03%]
TP53对多西他赛和Src抑制剂联合治疗效果的影响
Yun Sun Lee,Ji-Yoon Choi,Jeeyun Lee et al.
Yun Sun Lee et al.
The anticancer effects of Src kinase inhibitors are controversial. This study found an association between alterations in the TP53 gene and the synergy score for combination treatment with doxorubicin and an Src kinase inhibitor using human...
miR-142-3p attenuates breast cancer stem cell characteristics and decreases radioresistance in vitro [0.03%]
miR-142-3p降低乳腺癌干细胞特性并减少体外放射耐受性
Fabian M Troschel,Nicolas Böhly,Katrin Borrmann et al.
Fabian M Troschel et al.
Effectively targeting cancer stem cells, a subpopulation of tumorigenic, aggressive, and radioresistant cells, holds therapeutic promise. However, the effects of the microRNA miR-142-3p, a small endogenous regulator of gene expression on br...
Association of DFNA5, SYK, and NELL1 variants along with HPV infection in oral cancer among the prolonged tobacco-chewers [0.03%]
DFNA5、SYK和NELL1基因变异联合HPV感染在长期嚼食烟草的口腔癌患者中的关联研究
Sharbadeb Kundu,Vijayalakshmi Ramshankar,Akalesh Kumar Verma et al.
Sharbadeb Kundu et al.
Southeast Asia, especially India, is well known for the highest use of smokeless tobacco. These products are known to induce oral squamous cell carcinoma. However, not all long-term tobacco-chewers develop oral squamous cell carcinoma. In a...
Evaluation of tissue computed tomography number changes and dosimetric shifts after conventional whole-breast irradiation in patients undergoing breast-conserving surgery [0.03%]
乳腺癌保乳术后常规全乳照射后组织CT值变化及剂量学偏移的评估
Joo Hwan Lee,Dong Soo Lee,So Hyun Park et al.
Joo Hwan Lee et al.
The aim of this study was to assess tissue computed tomography (CT) number changes and corresponding dosimetric shifts in repeatedly performed simulation CT (re-sim CT) scans after conventionally fractionated irradiation in breast cancer pa...
Myeloid-derived suppressor cells and their role in gynecological malignancies [0.03%]
髓源性抑制细胞及其在妇科恶性肿瘤中的作用
Seiji Mabuchi,Eriko Yokoi,Naoko Komura et al.
Seiji Mabuchi et al.
Myeloid-derived suppressor cells are a heterogeneous population of immature myeloid cells that exhibit immunosuppressive activity (they block the proliferation and activity of both T cells and natural killer cells). In addition to their rol...
Transcription factor GATA4 associates with mesenchymal-like gene expression in human hepatoblastoma cells [0.03%]
转录因子GATA4与人类肝母细胞瘤细胞的间质基因表达相关联
Tea Soini,Katja Eloranta,Marjut Pihlajoki et al.
Tea Soini et al.
GATA4, a transcription factor crucial for early liver development, has been implicated in the pathophysiology of hepatoblastoma, an embryonal tumor of childhood. However, the molecular and phenotypic consequences of GATA4 expression in hepa...