Total cell-free DNA, carcinoembryonic antigen, and C-reactive protein for assessment of prognosis in patients with metastatic colorectal cancer [0.03%]
循环肿瘤DNA甲胎蛋白癌胚抗原C反应蛋白联合用于结直肠癌肝转移的预后预测模型研究
Karen-Lise Garm Spindler,Christina Demuth,Boe Sandahl Sorensen et al.
Karen-Lise Garm Spindler et al.
In late-stage metastatic colorectal cancer, difficult treatment decisions should incorporate a thorough evaluation of the patient's general condition and subject for shared decision making. Assessment of the individual patients' prognosis i...
VDR gene FokI polymorphism as a poor prognostic factor for papillary thyroid cancer [0.03%]
喉状甲状腺癌的不良预后因素-VDR基因FokI多态性
Selvihan Beysel,Nilnur Eyerci,Ferda Alparslan Pinarli et al.
Selvihan Beysel et al.
This is the first study to investigate the effect of vitamin D receptor ( VDR) gene single-nucleotide polymorphisms on the clinicopathologic features of papillary thyroid cancer in Turkey. A total of 165 patients with papillary thyroid canc...
Cell-adhesion molecules and their soluble forms: Promising predictors of "tumor progression" and relapse in leukemia [0.03%]
细胞黏附分子及其可溶性形式有望成为预测白血病“肿瘤进展”和复发的指标
Ieda Cristina Cunha Ferreira E Fonseca,Felipe Andrés Cordero da Luz,Isadora Akemi Uehara et al.
Ieda Cristina Cunha Ferreira E Fonseca et al.
Some surface markers are used to discriminate certain leukemic subpopulations that retain a greater oncogenic potential than others, and, for this reason, they were termed as leukemic stem cells, similar to the concept of cancer stem cells ...
Nivolumab in never-smokers with advanced squamous non-small cell lung cancer: Results from the Italian cohort of an expanded access program [0.03%]
尼沃单抗在非小细胞肺癌不吸烟患者中的疗效：来自一个扩大可及性项目的意大利队列研究结果
Marina Chiara Garassino,Lucio Crinò,Annamaria Catino et al.
Marina Chiara Garassino et al.
Objectives:: Never-smokers may be a distinct subgroup among patients with advanced non-small cell lung cancer, appearing to benefit less from immunotherapy than smokers. We report results from never-smokers enrolled in th...
B7-H3 and B7-H4 expression in phyllodes tumors of the breast detected by RNA in situ hybridization and immunohistochemistry: Association with clinicopathological features and T-cell infiltration [0.03%]
乳腺叶状肿瘤中B7-H3和B7-H4的表达及其与临床病理特征和T细胞浸润的关系——RNA原位杂交和免疫组化检测结果
Ga-Eon Kim,Nah Ihm Kim,Min Ho Park et al.
Ga-Eon Kim et al.
Phyllodes tumors are rare biphasic breast tumors with the potential for both local recurrence and distant metastasis. The aberrant expression of B7-H3 and B7-H4 B7 molecules could be potential targets for future development of immunotherape...
The relationship between chemokines CCL2, CCL3, and CCL4 with the tumor microenvironment and tumor-associated macrophage markers in colorectal cancer [0.03%]
细胞因子CCL2、CCL3和CCL4与结直肠癌肿瘤微环境及肿瘤相关巨噬细胞标志物的关系研究
Marjorie De la Fuente López,Glauben Landskron,Daniela Parada et al.
Marjorie De la Fuente López et al.
A complex network of chemokines can influence cancer progression with the recruitment and activation of hematopoietic cells, including macrophages to the supporting tumor stroma promoting carcinogenesis and metastasis. The aim of this study...
Dysregulated cancer cell transdifferentiation into erythrocytes is an additional metabolic stress in hepatocellular carcinoma [0.03%]
肝癌细胞向红细胞的异常转分化是代谢应激的一个额外因素
Abigail Hughes,Gurtej K Dhoot
Abigail Hughes
A number of human and canine hepatocellular carcinoma tissues showed clear signs of hypoxia indicated by HIF1α-activation and the presence of large clusters of cells resembling erythrocytes at different stages of nuclear elimination withou...
MicroRNA-23b and microRNA-27b plus flutamide treatment enhances apoptosis rate and decreases CCNG1 expression in a castration-resistant prostate cancer cell line [0.03%]
miR-23b和miR-27b联合氟他胺处理提高了去势抵抗性前列腺癌细胞系的凋亡率并降低CCNG1表达水平
Ruan Ca Pimenta,Nayara I Viana,Gabriela Q Amaral et al.
Ruan Ca Pimenta et al.
The acquisition of a castration-resistant prostate cancer phenotype by prostate cancer cells is the alteration that has the worst prognosis for patients. The aim of this study was to evaluate the role of the microRNAs-23b/-27b as well as th...
Dual loss of USP10 and p14ARF protein expression is associated with poor prognosis in patients with small intestinal adenocarcinoma [0.03%]
USP10和p14ARF蛋白共表达丢失与小肠腺癌患者预后不良相关
Joon Seon Song,Joo Mi Yi,Hanbyoul Cho et al.
Joon Seon Song et al.
Oncogene-induced senescence occurs following oncogene activation in normal cells and is considered as a critical tumor-suppressing mechanism. Ubiquitin-specific protease 10 (USP10) has been reported to play a vital role in oncogene-induced ...
Tamoxifen suppresses paclitaxel-, vincristine-, and bortezomib-induced neuropathy via inhibition of the protein kinase C/extracellular signal-regulated kinase pathway [0.03%]
他莫昔芬通过抑制蛋白激酶C/细胞外信号调节激酶途径来抑制紫杉醇、长春新碱和硼替佐米引起的神经病変
Masanobu Tsubaki,Tomoya Takeda,Mikihiro Matsumoto et al.
Masanobu Tsubaki et al.
Chemotherapy-induced neuropathy is a highly problematic, dose-limiting effect of potentially curative regimens of cancer chemotherapy. When neuropathic pain is severe, patients often either switch to less-effective chemotherapy agents or ch...