Calcineurin homologous protein isoform 2 supports tumor survival via the sodium hydrogen exchanger isoform 1 in non-small cell lung cancer [0.03%]
钙神经激酶同源蛋白异构体2通过钠氢交换器同种型1支持非小细胞肺癌肿瘤存活
Wayne Taylor Cottle,Clarice Hayley Wallert,Kristine Kay Anderson et al.
Wayne Taylor Cottle et al.
Maintaining intracellular pH is crucial for preserving healthy cellular behavior and, when dysregulated, results in increased proliferation, migration, and invasion. The Na+/H+ exchanger isoform 1 is a highly regulated transmembrane antipor...
Lucyna Matusewicz,Aleksander Czogalla,Aleksander F Sikorski
Lucyna Matusewicz
Although it could be speculated that almost everything has been said concerning the use of statins in cancer therapy, statins as anticancer drugs have both committed supporters and opponents, for whom the dispute about the legitimacy of sta...
Characterization of Chilean patients with sporadic colorectal cancer according to the three main carcinogenic pathways: Microsatellite instability, CpG island methylator phenotype and Chromosomal instability [0.03%]
根据三种主要致癌途径对散发性结直肠癌患者进行特征分析：微卫星不稳定性，CpG岛甲基化表型和染色体不稳定性
Ana María Wielandt,Claudia Hurtado,Mauricio Moreno C et al.
Ana María Wielandt et al.
Molecular classification of colorectal cancer is difficult to implement in clinical settings where hundreds of genes are involved, and resources are limited. This study aims to characterize the molecular subtypes of patients with sporadic c...
FAS and FASL variations in outcomes of tobacco- and alcohol-related head and neck squamous cell carcinoma patients [0.03%]
FAS和FASL基因多态性在影响头颈部鳞癌患者预后的研究
Ericka Francislaine Dias Costa,Tathiane Regine Penna Lima,Leisa Lopes-Aguiar et al.
Ericka Francislaine Dias Costa et al.
Radiotherapy and cisplatin lead to cell killing in head and neck squamous cell carcinoma patients, but adverse events and response to treatment are not the same in patients with similar clinicopathological aspects. The aim of this prospecti...
Label-free proteomics reveals serum proteins whose levels differ between pancreatic ductal adenocarcinoma patients with short or long survival [0.03%]
无标签蛋白质组学发现胰腺导管腺癌患者生存期长短相关的血清蛋白水平差异
Matilda Holm,Mayank Saraswat,Sakari Joenväärä et al.
Matilda Holm et al.
Pancreatic ductal adenocarcinoma is the most common and aggressive type of pancreatic cancer, with a 5-year survival rate that is less than 10%. New biomarkers to aid in predicting the prognosis of pancreatic ductal adenocarcinoma patients ...
Adewale Oluwaseun Fadaka,Olalekan Olanrewaju Bakare,Ashley Pretorius et al.
Adewale Oluwaseun Fadaka et al.
Colorectal cancer is the second and third most common cancer in men and women, respectively, worldwide. Alterations such as genetic and epigenetic are common in colorectal cancer and are the basis of tumor formation. The exploration of the ...
Evaluating macrophage migration inhibitory factor 1 expression as a prognostic biomarker in colon cancer [0.03%]
评估巨噬细胞迁移抑制因子1表达作为结直肠癌预后生物标志物的价值
Lina Olsson,Gudrun Lindmark,Marie-Louise Hammarström et al.
Lina Olsson et al.
Objective: Several studies indicate that macrophage migration inhibitory factor 1 plays a role for tumor progression in colon cancer. We investigated whether determination of migration inhibitory factor 1 mRNA expression ...
ΔKi67 proliferation index as independent predictive and prognostic factor of outcome in luminal breast cancer: data from neoadjuvant letrozole-based treatment [0.03%]
Ki67增殖指数可作为预测和预示 Luminal型乳腺癌新辅助治疗效果的独立指标：来曲唑为基础的新辅助治疗数据
A Ianza,F Giudici,C Pinello et al.
A Ianza et al.
A key tool for monitoring breast cancer patients under neoadjuvant treatment is the identification of reliable predictive markers. Ki67 has been identified as a prognostic and predictive marker in ER-positive breast cancer. Ninety ER-positi...
KCNB1 gene polymorphisms and related indel as predictor biomarkers of treatment response for colorectal cancer - toward a personalized medicine [0.03%]
钾通道基因多态性及插入/缺失变异作为预测结直肠癌治疗反应的生物标志物-向个体化医学发展
Mouadh Barbirou,Ikram Sghaier,Sinda Bedoui et al.
Mouadh Barbirou et al.
The KCNB1 gene variants were differentially associated with cancers. However, their association with colorectal cancer has not yet been explored. We investigated the contribution of the KCNB1 gene variants rs3331, rs1051295, and indel (inse...
Contributions of HOX genes to cancer hallmarks: Enrichment pathway analysis and review [0.03%]
HOX基因对癌症标志的贡献：丰富途径分析和综述
Danielle Barbosa Brotto,Ádamo Davi Diógenes Siena,Isabela Ichihara de Barros et al.
Danielle Barbosa Brotto et al.
Homeobox genes function as master regulatory transcription factors during development, and their expression is often altered in cancer. The HOX gene family was initially studied intensively to understand how the expression of each gene was ...