A review on the role of CAFs and CAF-derived exosomes in progression and metastasis of digestive system cancers [0.03%]
癌相关成纤维细胞及其衍生的外泌体在消化系统肿瘤进展和转移中的作用研究进展
Bahare Zarin,Laleh Rafiee,Parnaz Daneshpajouhnejad et al.
Bahare Zarin et al.
Cancers evolve as a result of the accelerated proliferation of cancer cells in a complicated, enriched, and active microenvironment. Tumor microenvironment (TME) components are the master regulators of any step of cancer development. The tu...
Angiogenesis' related genetic variants alter clinical features and prognosis of diffuse large B-cell lymphoma patients [0.03%]
血管生成相关遗传变异改变弥漫性大B细胞淋巴瘤患者的临床特征及预后
Angelo Borsarelli Carvalho Brito,Marcia Torresan Delamain,Marcello Ferreti Fanelli et al.
Angelo Borsarelli Carvalho Brito et al.
Objectives: Single nucleotide variants (SNVs) in vascular endothelial growth factor A (VEGFA) and VEGFA receptor (KDR) genes confer different inherited abilities in angiogenesis (AG) pathway. We aimed in the present study...
Validation of a clinical blood-based decision aid to guide immunotherapy treatment in patients with non-small cell lung cancer [0.03%]
非小细胞肺癌患者免疫治疗临床血液决策辅助工具的验证研究
Mirte Muller,Roland Hoogendoorn,Ruben J G Moritz et al.
Mirte Muller et al.
Background: The widespread introduction of immunotherapy in patients with advanced non-small cell lung cancer (NSCLC) has led to durable responses but still many patients fail and are treated beyond progression. ...
Lack of CD44 overexpression and application of concurrent chemoradiotherapy with cisplatin independently indicate excellent prognosis in patients with HPV-positive oropharyngeal cancer [0.03%]
CD44不表达及同期放化疗对HPV阳性口腔癌患者预后的影响
Beata Biesaga,M Kołodziej-Rzepa,A Janecka-Widła et al.
Beata Biesaga et al.
Background: HPV-16 positivity in patients with squamous cell carcinoma of oropharynx (OPSCC) is associated with better prognosis. However, in more than 40% of HPV infected patients progression of cancer disease is observe...
Galectin-3: A factotum in carcinogenesis bestowing an archery for prevention [0.03%]
半乳糖凝集素3：一种在肿瘤发生中多才多艺的分子及其预防作用
T Jeethy Ram,Asha Lekshmi,Thara Somanathan et al.
T Jeethy Ram et al.
Cancer metastasis and therapy resistance are the foremost hurdles in oncology at the moment. This review aims to pinpoint the functional aspects of a unique multifaceted glycosylated molecule in both intracellular and extracellular compartm...
Impact of RARα and miR-138 on retinoblastoma etoposide resistance [0.03%]
RARα和miR-138对视网膜母细胞瘤表皮毒素抗性的影响研究
Maike Busch,Natalia Miroschnikov,Jaroslaw Thomas Dankert et al.
Maike Busch et al.
Background: Retinoblastoma (RB) is the most common childhood eye cancer. Chemotherapeutic drugs such as etoposide used in RB treatment often cause massive side effects and acquired drug resistances. Dysregulated genes and...
CA125: A superior prognostic biomarker for colorectal cancer compared to CEA, CA19-9 or CA242 [0.03%]
CA125是一个优于CEA、CA19-9或CA242的结直肠癌预后标志物
Kajsa Björkman,Harri Mustonen,Tuomas Kaprio et al.
Kajsa Björkman et al.
Objectives: The tumor stage represents the single most important prognostic factor for colorectal cancer (CRC), although more accurate prognostics remain much needed. Previously, we identified CA125 as an independent sign...