An Open-Label Trial Protocol to Test Menstrual Cycle Effects and Tolerance to Low-Dose Psilocybin in Healthy Menstruating Persons [0.03%]
一项开放标签试验方案，用于检验月经周期对健康女性小剂量致幻裸盖菇素耐受性和作用的影响
Farheen Mustak Kothiwala,Robin J Murphy,Malak Alshakhouri et al.
Farheen Mustak Kothiwala et al.
Background: Research on the therapeutic benefits of psychedelics, particularly psilocybin, is becoming increasingly popular. Unfortunately, most psychedelic research overlooks the menstrual cycle as a biological variable,...
Dexmedetomidine Alleviates Cardiomyocyte Senescence Induced by Ischemia-Reperfusion Injury via Inhibiting the MDH2/NF-κB Pathway [0.03%]
右美托咪定通过抑制MDH2/NF-κB途径缓解心肌细胞缺血再灌注损伤诱导的心肌细胞衰老
Gang Liu,Xiaoxuan Du
Gang Liu
Background: Myocardial ischemia-reperfusion (I/R) injury represents a key contributor to cardiac dysfunction and is associated with cardiomyocyte senescence. Dexmedetomidine (Dex) exhibits significant myocardial protectiv...
The co-regulation of NLRP3 inflammasome and autophagy for cardiovascular diseases [0.03%]
NLRP3炎症小体与自噬的共调节在心血管疾病中的作用
Shuxin Zheng,Huaqian Dou,Xiao Feng Zhang et al.
Shuxin Zheng et al.
Cardiovascular diseases (CVDs) represent a significant global public health challenge. Activation of the NLRP3 inflammasome contributes to CVD pathogenesis, while autophagy mitigates the condition by eliminating harmful metabolites. Further...
Comparative Efficacy and Safety of Telitacicept vs. Belimumab in Systemic Lupus Erythematosus: A Systematic Review and Meta-Analysis [0.03%]
泰利斯妥塞普与贝利尤单抗治疗系统性红斑狼疮的疗效和安全性比较：系统评价和.meta.分析
Young Ho Lee,Gwan Gyu Song
Young Ho Lee
Objective: This study was designed to assess the comparative efficacy and safety of telitacicept and belimumab in adult patients diagnosed with systemic lupus erythematosus (SLE). ...
Inflammatory conditions determine glucocorticoid effects on spontaneous or immunoglobulin-induced neutrophil death [0.03%]
炎症状态决定糖皮质激素对自发或免疫球蛋白诱导的中性粒细胞死亡的影响
Marjolaine Hugonnet,Darien Toledo,Giselle Hevia et al.
Marjolaine Hugonnet et al.
Neutrophils play a central role in the pathogenesis of inflammatory and autoimmune disorders. While glucocorticoids are potent anti-inflammatory agents, they are known to promote neutrophil survival, which may worsen neutrophil-driven condi...
Long-term Safety and Efficacy of Anifrolumab in Systemic Lupus Erythematosus: A Meta-Analysis of Randomized Controlled Trials, Extension Studies, and Real-World Cohorts [0.03%]
阿尼福如马布治疗系统性红斑狼疮长期安全性和有效性的meta分析：随机对照试验、扩展研究和真实世界队列数据分析
Young Ho Lee,Gwan Gyu Song
Young Ho Lee
Objectives: Anifrolumab, a type I interferon receptor antagonist, has shown effectiveness in treating moderate-to-severe systemic lupus erythematosus (SLE). To fully understand its long-term efficacy, glucocorticoid (GC)-...
Safety and efficacy of Efbemalenograstim alfa for patients at risk for chemotherapy-induced neutropenia: A Systematic review and Meta-analysis [0.03%]
艾贝马来诺格斯坦α预防化疗引起的中性粒细胞减少的安全性和疗效的系统评价和meta分析
Prasanjit Das,Sreejoi Dutta,Shampa Maji et al.
Prasanjit Das et al.
Introduction: Chemotherapy-induced neutropenia (CIN) and its severe complication, febrile neutropenia, remain major challenges in oncology. Although granulocyte colony-stimulating factors (GCSFs) have reduced the incidenc...
Retraction Statement [0.03%]
撤稿说明
The article "Hypoxia-Treated Adipose Mesenchymal Stem Cells Derived Exosomes Enhance the Therapeutic Effects on Unilateral Ureteral Obstruction Mice" [Pharmacology. 2025;110(3):165-177; https://doi.org/10.1159/000542609] by Chi Zhang, Longj...
Antiplatelet Therapy After Endovascular Intracranial Aneurysm Surgery: Comparative Effectiveness and Safety Insights from Systematic Review and Meta-Analysis [0.03%]
基于系统性回顾和荟萃分析的颅内动脉瘤手术后的抗血小板治疗：疗效及安全性探讨
Qiuling Chen,Yaowang Lin,Cheng Liu et al.
Qiuling Chen et al.
Background: Endovascular treatment of intracranial aneurysms-particularly stent-assisted coiling (SAC) and flow diversion (FD)-requires antiplatelet (AP) therapy to prevent thromboembolic complications. However, standard ...
Ciprofol versus Propofol for General Anesthesia Induction in Major Orthopedic Surgery: Efficacy and Safety Analyses Pertaining to Anesthetic Parameters [0.03%]
用于骨科大手术的全身麻醉诱导的丙泊酚与右美托咪定的效果和安全性分析：与麻醉参数相关的分析
Xia Yao,Hui Wang,Yue Zhang et al.
Xia Yao et al.
Background: Propofol is the standard agent for anesthesia induction but is frequently associated with injection-site pain and hemodynamic instability. Ciprofol (HSK3486), a novel GABAA receptor agonist, has emerged as a p...