Establishment of a novel organoid line from esophageal squamous cell carcinoma with cytoplasmic vacuoles: Association of autolysosome swelling with vacuole formation [0.03%]
建立一种新型食管鳞状细胞癌伴胞质空泡的类器官系：自溶酶体肿胀与空泡形成的关系
Shunsuke Fujita,Tomotaka Shibata,Haruto Nishida et al.
Shunsuke Fujita et al.
Introduction: We experienced a case of esophageal squamous cell carcinoma (ESCC) exhibiting mucus-negative cytoplasmic vacuoles. The carcinoma cells with vacuoles were positive for p63, a marker of squamous cell carcinoma...
Unravelling the Tumourigenesis Mechanisms of Oncocytic Cell Tumours: Discoveries from a Comparative Omics Study [0.03%]
oncogenic细胞肿瘤致癌机制的解密：一种比较组学研究的新发现
Sule Canberk,Marta Ferreira,Arnaud Da Cruz Paula et al.
Sule Canberk et al.
Oncocytic cell tumours (OCTs), previously referred to as Hürthle cell tumors of the thyroid, are a subset of thyroid and endocrine neoplasms that pose diagnostic and therapeutic challenges owing to their unpredictable clinical behaviour. G...
Grainyhead-like 2 expression is associated with disease progression, chemoresistance and poor survival in tubo-ovarian high-grade serous carcinoma [0.03%]
粒样细胞滑移相关蛋白2表达与输卵管卵巢高级别浆液性癌的疾病进展、耐药及不良预后有关
Ben Davidson,Silke Hauladen,Arild Holth et al.
Ben Davidson et al.
Introduction: Grainyhead-like 2 (GRHL2) regulates epithelial-to-mesenchymal transition (EMT) in cancer. This study analyzed the expression and prognostic role of GRHL2 in high-grade serous carcinoma (HGSC). ...
Myeloid neoplasms with evidence of the additive / cumulative effect of molecular genetic alterations that "pave the way" to a specific disease category or entity: lessons learned from cases submitted to the 22nd Meeting of the European Association for Haematopathology/Society of Hematopathology (EA4HP/SH) Bone Marrow Workshop organized [0.03%]
具有分子遗传学改变的证据髓系肿瘤，这些改变“为特定疾病类别或实体铺平道路”：从第22届欧洲血液病理协会/造血组织病理学会（EAHP/SH）骨髓工作组提交的案例中得到的经验教训
Alexandar Tzankov,Anna Green,Roos Leguit et al.
Alexandar Tzankov et al.
Myeloid neoplasms (MN) represent genetic disorders with clonal overgrowth of cells bearing mutations of oncogenes and/or tumor suppressor genes. Distinct co-mutation patterns are associated with specific MN. MN progenitor cells retain plast...
HPV ctDNA as a Biomarker for Monitoring Disease Progression in HPV16/18-Associated Cervical Cancer [0.03%]
HPV ctDNA作为监测高危型HPV16/18型阳性宫颈癌疾病进展生物标志物的研究
Meejeong Kim,Miseon Lee,Jun Kang et al.
Meejeong Kim et al.
Introduction: Cervical cancer, primarily driven by oncogenic HPV16/18, often relapses despite standard treatments. HPV circulating tumor DNA (ctDNA), which reflects tumor-derived genetic material in the bloodstream, has e...
Aberrant cytoplasmic p53 expression and its correlation with TP53 mutation status and functional implications in stage II and III colorectal cancer [0.03%]
结肠直肠癌II期和III期中异常胞浆p53表达及其与TP53突变状态相关性及功能意义的研究
Meejeong Kim,Lingyan Jin,Hye-Yeong Jin et al.
Meejeong Kim et al.
Introduction: TP53 mutation is frequently observed in colorectal cancer (CRC) and is often linked to associated with immunohistochemical p53 expression patterns. Recent studies have identified cytoplasmic p53 expression i...
Expression of FUBP1 in gastrointestinal stromal tumors and its regulation of cell proliferation, migration, and invasion [0.03%]
FUBP1在胃肠道间质瘤中的表达及其对细胞增殖、迁移和侵袭的调控作用
Zhigao Zhang,Fucheng Zhang,Shubao Zhang et al.
Zhigao Zhang et al.
Introduction: This study aimed to observe the expression of far upstream element binding protein 1 (FUBP1) in gastrointestinal stromal tumors (GISTs) and explore its impact on the biological behavior of GIST cells. ...
2,3-Pyridinedicarboxylate is associated with shorter recurrence-free survival in patients with hypopharyngeal squamous cell carcinoma [0.03%]
2,3-吡啶二甲酸与下咽鳞癌患者较短的无病生存期相关
Hiroki Takase,Takao Fujisawa,Ryuichi Hayashi et al.
Hiroki Takase et al.
Introduction: Metabolites are associated with the biology of cancer; however, no metabolites related to prognosis have been identified in head and neck cancer. This study aimed to identify metabolites associated with prog...
Predictive histopathological markers for upstaging to invasive carcinoma after a biopsy diagnosis of ductal carcinoma in situ (DCIS) of the breast: a hypothesis-generating systematic review [0.03%]
乳腺原位导管癌（DCIS）活检诊断后升级为侵袭性癌的预测病理标志物：一种假说生成系统评价
Julia A M Riggi,Ibrahim Kassem,Christine Galant et al.
Julia A M Riggi et al.
Introduction Around 25% of patients with a biopsy diagnosis of pure ductal carcinoma in situ (DCIS) will be upstaged to invasive breast carcinoma (IBC) after surgery. Because of this upstaging risk, patients with high grade DCIS frequently ...