Ruo-Bing Wang,Xuan Wang,Kun-Kun Han et al.
Ruo-Bing Wang et al.
Therapy based on chimeric antigen receptor-engineered invariant natural killer T (iNKT) cells (CAR-NKT cells) is an innovative cellular immunotherapy strategy that offers advantages over conventional CAR-T cell therapy in the treatment of s...
Significantly Decreased Progesterone Receptor Expression in Corded and Hyalinized Variant of Endometrioid Adenocarcinoma: A Potential Cause of Resistance to Progestin Treatment [0.03%]
柱状及玻璃样变子宫内膜腺癌中孕激素受体表达显著降低：可能是孕酮治疗抵抗的原因
Uiree Jo,Bong-Hee Park,Chang Ohk Sung et al.
Uiree Jo et al.
Introduction: The corded and hyalinized variant of endometrioid adenocarcinoma (CHEC) is a biphasic tumor composed of cords of epithelioid and/or spindle cells (CoES) within hyalinized or chondroid stroma, which is often ...
Malignant progression of SEGA-imitating fibrous meningioma in a child carrying a germline CHEK2 mutation [0.03%]
携带CHEK2胚系突变的儿童患者脑膜瘤恶性进展转变为类似SEGA肿瘤病例报告
Bartosz Szmyd,Marcin Braun,Agata Pastorczak et al.
Bartosz Szmyd et al.
Background: The subependymal giant cell astrocytoma (SEGA) predominantly occurs in patients with tuberous sclerosis. Here, we present an unusual aggressive transformation of SEGA-imitating fibrous meningioma in a child ca...
Agnese Orsatti,Fernanda Fernandes-Pontes,João Ricardo E Silva et al.
Agnese Orsatti et al.
Background: Renal cell carcinoma (RCC) is a heterogeneous disease, with the last World Health Organization (WHO) classification introducing several novel entities, among which the molecularly defined RCCs. This growing co...
Kemal Behzatoğlu
Kemal Behzatoğlu
Background: In cancers, key prognostic determinants such as clinical stage and mutational load are well recognized. However, mucinous adenocarcinomas (MACs) display distinct biological behavior, as a large proportion of t...
ThinPrep® whole-slide digital images vs conventional microscopy in NILM, ASC-US and LSIL cervical lesions: European Federation of Cytological Societies (EFCS) study [0.03%]
薄层细胞学全片数字化图像在宫颈NILM、ASC-US和LSIL病变中与常规显微镜检查的比较：欧洲细胞学会（EFCS）的研究
Ester Puntonen,Sara Bazzon,Massimo Bongiovanni et al.
Ester Puntonen et al.
Introduction: High inter- and intraobserver variability is acknowledged in Negative for Intraepithelial Lesion or Malignancy (NILM), Atypical Squamous Cells of Undetermined Significance (ASC-US) and low-grade squamous int...
Tissue-Based Multiomic Exploratory Analysis of the uPa/uPAR System and Matrix Metalloproteinases in SARIFA-Positive Gastrointestinal Cancers [0.03%]
基于组织的多组学探索性分析SARIFA阳性消化道癌症中的uPA/uPAR系统和基质金属蛋白酶
Nic G Reitsam,Bianca Grosser,Sebastian Dintner et al.
Nic G Reitsam et al.
Introduction: We recently proposed SARIFA (Stroma AReactive Invasion Front Areas), defined as direct tumour-adipocyte interaction, as an H&E-based histopathologic biomarker in gastrointestinal cancers, particularly gastri...
REV7 expression is associated with tumor cell growth and cisplatin resistance in gallbladder adenocarcinoma [0.03%]
REV7表达与胆囊腺癌肿瘤细胞增殖及顺铂耐药相关性研究
Masahiro Matsushita,Takuya Kato,Yasutaka Sakurai et al.
Masahiro Matsushita et al.
Introduction: REV7 functions in various biological processes, including the DNA damage response. REV7 expression has been linked to the prognosis and chemoresistance in several human cancers. This study investigated the s...
Influence of the molecular subtype-dependent immune microenvironment of metastatic axillary lymph nodes on breast cancer patient outcomes [0.03%]
转移性腋窝淋巴结分子亚型依赖性免疫微环境对乳腺癌患者预后的影响
Carlos López,Laia Reverté,Ramon Bosch Príncep et al.
Carlos López et al.
Metastasis in the axillary lymph nodes (ALNs) occurs in 30-50% of breast cancers (BCs), where residing immune cells play a crucial role in disease progression. Specifically at diagnosis, the immune elements infiltrating the primary tumour a...
Assessing Tumour Budding in Lung Squamous Cell Carcinoma: A Comparative Analysis of Digital Whole Slide Imaging and Light Microscopy [0.03%]
肺癌鳞状细胞癌肿瘤芽的评估：数字全视野成像与光学显微镜比较分析
Mark Keyter,Stefano Lucà,Marie Mailard et al.
Mark Keyter et al.
Introduction Tumour budding (TB) is an emerging prognostic marker in solid cancers and has recently been endorsed by the IASLC as a component of grading in lung squamous cell carcinoma (LUSC). With the growing adoption of digital pathology,...