Single-cell transcriptome sequencing and analysis provide a new approach for the treatment of small cell neuroendocrine carcinoma of the cervix [0.03%]
单细胞测序技术或可改变宫颈小细胞神经内分泌癌的治疗格局
Lewei He,Yuling Wu,Mingyi Lv et al.
Lewei He et al.
Introduction: Small cell neuroendocrine carcinoma of the cervix (SCNECC) is a rare gynecologic malignant tumor, which is lack of systematic research. In order to investigate its molecular characteristics, origin and patho...
Hormone Regulation of Corticotropin-Releasing Factor Receptor 1 in the Female Mouse Brain [0.03%]
促肾上腺皮质激素释放因子受体1的激素调节机制及其在小鼠脑内的作用分布规律研究
Rose M De Guzman,Jason S Jacobskind,Zachary J Rosinger et al.
Rose M De Guzman et al.
Introduction: Corticotropin-releasing factor receptor 1 (CRFR1) is a key regulator of neuroendocrine and behavioral stress responses. Previous studies have demonstrated that CRFR1 in certain hypothalamic and preoptic brai...
Lu-PRRT Used More Intensively on Advanced Gastro-Entero-Pancreatic and Lung Neuroendocrine Neoplasms: Preliminary Results on Toxicity from a Randomized Study [0.03%]
镥-PRRT治疗晚期胃肠胰神经内分泌瘤和肺癌神经内分泌肿瘤更密集：一项随机研究的初步毒性结果
Ilaria Grassi,Silvia Nicolini,Irene Marini et al.
Ilaria Grassi et al.
Introduction: Lu-PRRT in neuroendocrine tumors is usually delivered with a total cumulative activity (TCA) of 29.6 GBq, divided into 4 cycles and with fixed interval between cycles (IBCs) of 8 weeks. Based on previous rad...
A Comprehensive Target Panel Allows to Extend the Genetic Spectrum of Neuroendocrine Tumors [0.03%]
全面的目标检测面板可扩展神经内分泌肿瘤的遗传谱系
Uliana A Tsoy,Polina S Sokolnikova,Ekaterina N Kravchuk et al.
Uliana A Tsoy et al.
Introduction: Neuroendocrine tumors (NETs) frequently have a genetic basis, and the range of genes implicated in NET development continues to expand. Application of targeted gene panels (TGPs) in next-generation sequencin...
Potential Cognitive Decline Linked to Electronegative L5 in Type 2 Diabetes: A Holo-Hilbert Spectral Analysis [0.03%]
2型糖尿病潜在认知衰退与L5电负性之间的联系：全霍尔希尔伯特谱分析法探究
Ping-Song Chou,Mei-Yueh Lee,Wen-Sheng Chang et al.
Ping-Song Chou et al.
Introduction: Patients with type 2 diabetes mellitus (T2DM) have an increased risk of cognitive impairment. In this study, we investigated the effect of L5 - an electronegative subfraction of low-density lipoprotein chole...
Recent Advances in the Understanding of Gonadotrope Lineage Differentiation in the Developing Pituitary [0.03%]
近年下丘脑垂体生殖细胞分化研究进展
Charles Le Ciclé,Joëlle Cohen-Tannoudji,David L&#x;Hôte
Charles Le Ciclé
Background: The pituitary gland is a vital endocrine organ regulating body homoeostasis through six hormone-secreting cell types. Among these, pituitary gonadotrope cells are essential for reproductive function. Throughou...
Characteristic Activation Pattern and Network Connectivity of Prefrontal Cortex in Patients with Type 2 Diabetes Mellitus and Major Depressive Disorder during a Verbal Fluency Task: A Functional Near-Infrared Spectroscopy Study Based on Network-Based Statistic Prediction [0.03%]
基于网络统计预测的基于功能近红外光谱技术的2型糖尿病合并抑郁症患者在词语流畅度任务中前额叶皮质激活模式及网络连接特征分析研究
Jia-Ming Zhang,Xiao-Bo Liu,Yu-Xi Li et al.
Jia-Ming Zhang et al.
Introduction: Type 2 diabetes mellitus (T2DM) and major depressive disorder (MDD) together occur frequently among the elderly population. However, the inconsistency in assessments and limited medical resources in the comm...
Neuroendocrine Tumors and Survival Rates in Multiple Endocrine Neoplasia Type 1 Patients: Impact of Gender Difference [0.03%]
多发性内分泌肿瘤1型患者神经内分泌肿瘤与生存率差异及性别影响
Roberta Modica,Alessia Liccardi,Roberto Minotta et al.
Roberta Modica et al.
Introduction: Multiple endocrine neoplasia type 1 (MEN-1) is the most common inherited syndrome associated with NET development and gender-specific differences are emerging in neuroendocrine tumors (NETs). This study aime...
Comparative Targeted Genome Profiling between Solid and Liquid Biopsies in Gastroenteropancreatic Neuroendocrine Neoplasms: A Proof-of-Concept Pilot Study [0.03%]
胃肠胰神经内分泌肿瘤的实体瘤和液体活检比较靶向基因组分析：概念验证试点研究
Irene Gagliardi,Federica Campolo,Patricia Borges de Souza et al.
Irene Gagliardi et al.
Introduction: Clinical presentation and genetic profile of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are highly variable, hampering their management. Sequencing of circulating tumor DNA from liquid biopsy (L...
Shruti Sasikumar,Suraj Unniappan
Shruti Sasikumar
Background: The novel coronavirus strain SARS-CoV-2 triggered the COVID-19 pandemic with severe economic and social ramifications. As the pathophysiology of SARS-CoV-2 infection in the respiratory system becomes more unde...