Cocaine self-administration differentially modulates the content of cholesterol, progesterone and testosterone in the brain and plasma of male rats [0.03%]
可卡因自我给药对雄性大鼠脑和血浆中胆固醇、孕酮和睾丸激素含量有差异性的调节作用
William B Inabinett,Shiyu Wang,Paige M Estave et al.
William B Inabinett et al.
Introduction: Chronic cocaine exposure results in changes in circulating steroid hormones, which is known to be associated with cocaine-seeking and taking behavior. However, whether cocaine also alters the brain content o...
Involvement of the AVP/OT system and lateral septum in the modulation of anxiety/depression caused by 14-week and 20-week social isolation [0.03%]
AVP/OT系统和外侧隔核在14周和20周社交隔离引起焦虑/抑郁的调控中的作用
Jing Liu,Weizheng Zhang,Yuting Bai et al.
Jing Liu et al.
Introduction: Chronic social isolation (CSI) stress leads to numerous maladaptive changes in physiology and psychology, however, very little is known about the effects of longer time-scale CSI and there are divergent view...
Ectopic CRH/ACTH-Co-Secreting Neuroendocrine Tumors Leading to Cushing's Disease - A Case Presentation and Literature Review [0.03%]
导致库欣病的异位CRH/ACTH共分泌神经内分泌肿瘤--一个病例展示和文献回顾
Jasmin Ewert,Maximilian Seidl,Jann Achim Hommen et al.
Jasmin Ewert et al.
Adrenocorticotropic hormone (ACTH) and corticotropin-releasing hormone (CRH) are essential regulators of cortisol production within the hypothalamic-pituitary-adrenal (HPA) axis. Elevated cortisol levels, resulting from excessive ACTH, can ...
Factors influencing costs of cancer care for patients with neuroendocrine neoplasms [0.03%]
影响神经内分泌肿瘤患者癌症治疗费用的因素分析
Martin O Weickert
Martin O Weickert
Background: Neuroendocrine neoplasms (NENs) are comparatively rare tumours. However, prevalence is increasing steeply, related to rising incidence, earlier detection, and prolonged survival in many cases of metastatic NEN...
David Vaudry
David Vaudry
No abstract. The Author(s). Published by S. Karger AG, Basel.
Editorial
Neuroendocrinology. 2025 Feb 5:1-4. DOI:10.1159/000543954 2025
Cabozantinib in the Treatment of Neuroendocrine Neoplasms: Insights Across Different Tumor Origins [0.03%]
卡博替尼治疗神经内分泌肿瘤：不同肿瘤起源的见解
Giovanni Vitale,Ilona Rybinska,Giulia Arrivi et al.
Giovanni Vitale et al.
Background: Neuroendocrine neoplasms (NENs) are a heterogeneous group of tumors arising from neuroendocrine cells, exhibiting a wide range of behaviours from indolent to highly aggressive forms. Treatment options remain l...
The hypothalamus and pituitary gland regulate reproduction and are involved in the development of polycystic ovary syndrome [0.03%]
下丘脑和垂体对生殖的调节及其在多囊卵巢综合征发病机制中的作用
Bin-Yang Long,Xipeng Liao,Xin Liang
Bin-Yang Long
Background Polycystic ovary syndrome is a complex condition with unclear mechanisms, posing a challenge for prevention and treatment of PCOS. The role of the hypothalamus and pituitary gland in regulating female reproduction is critical. Ab...
Impact of indoleamine 2,3-dioxygenase enzyme activity in neuroendocrine tumors [0.03%]
吲哚胺2,3-双氧酶酶活性对神经内分泌肿瘤的影响
Camilla Mancini,Giulia Pecora,Gerardo Salerno et al.
Camilla Mancini et al.
Introduction: Indoleamine-2,3-dioxygenase (IDO) converts L-tryptophan (T) to L-kynurenine (K) resulting in an immunosuppressive microenvironment. Aim of the current study is to evaluate in patients with neuroendocrine tum...
Genetic associations between obesity and brain cortical thickness: combined genetic correlation, multi-trait meta- analysis and Mendelian randomization [0.03%]
肥胖与大脑皮层厚度的遗传关联：综合遗传相关性、多特征元分析和孟德尔随机化研究
Jiankun Chen,Simin Pan,Yingfei Tan et al.
Jiankun Chen et al.
Introduction: Obesity may lead to cognitive impairment and neuropsychiatric disorders, which are associated with changes in the brain cortical structure, particularly in cortical thickness. However, the exact genetic asso...
Maternal diet and vulnerability to cognitive impairment in adulthood: possible link with Alzheimer's disease? [0.03%]
母体饮食与成人认知障碍的易感性：可能与阿尔茨海默病有关？
Laetitia Merle,Marialetizia Rastelli,Frédérique Datiche et al.
Laetitia Merle et al.
Aging is the main risk factor for developing cognitive impairments and associated neurodegenerative diseases. However environmental factors, including nutritional health, are likely to promote or reduce cognitive impairments and neurodegene...