The Causal Role of Gut Microbiota and Immune Cell Mediation in Gastroenteropancreatic Neuroendocrine Neoplasms: A Mendelian Randomization Study [0.03%]
胃肠道微生物群和免疫细胞在胃肠道胰神经内分泌肿瘤中的因果作用:孟德尔随机化研究
Zhichen Jiang,Pengcheng Ma,Fangxia Wang et al.
Zhichen Jiang et al.
Background: Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are a diverse group of tumors arising from neuroendocrine cells, often characterized by slow growth and subtle symptoms, leading to advanced-stage dia...
Lipid Profile Differences in Monomeric Hyperprolactinemia, Macroprolactinemia, and Healthy Controls: A Comparative Analysis [0.03%]
单体高催乳素血症、巨催乳素血症和健康对照的血脂谱差异:一项比较分析
Sami Bahçebaşı,Ferhat Gökay,Yasin Şimşek
Sami Bahçebaşı
Introduction: This study aimed to investigate the effects of different prolactin isoforms - specifically macroprolactin and monomeric prolactin - on lipid metabolism across various subtypes of hyperprolactinemia. ...
Are there connections between the neuroendocrine and dopamine systems in bipolar disorder? [0.03%]
双相情感障碍中神经内分泌系统和多巴胺系统之间存在联系吗?
Jacqueline Trouillas,Bruno Claustrat,Emmanuel Henry et al.
Jacqueline Trouillas et al.
Background: Bipolar disorder (BPD) represents a frequent and disabling disease, characterized by the occurrence of extreme mood swings leading to episodes of depression or mania. Although dysfunctions in dopamine (DA) neu...
John Ramage,Raj Srirajaskanthan
John Ramage
Editorial
Neuroendocrinology. 2025 Aug 1:1-7. DOI:10.1159/000547728 2025
Loss of DAXX/ATRX protein expression results in ischemia resistance and radiation sensitivity in pancreatic neuroendocrine tumor cells and is associated with improved response to trans-arterial radio-embolization [0.03%]
DAXX/ATRX蛋白表达丢失导致胰腺神经内分泌肿瘤细胞缺血抵抗和放射敏感性增强,并且与接受血管内放射栓塞治疗的临床反应改善相关
Jessica C Puzzuoli,Caleb Solivio,Gavin Yuan et al.
Jessica C Puzzuoli et al.
Ntroduction: Metastatic liver pancreatic neuroendocrine tumors (PNETs) can be treated with ischemia-based (trans-arterial embolization [TAE]/trans-arterial chemo-embolization [TACE]) or radiation-based (trans-arterial rad...
Steroids and one-carbon metabolism: clinical implications in endocrine disorders [0.03%]
甾体和一碳代谢:内分泌疾病的临床意义
Nicolas Scheyer,Rosa-Maria Guéant-Rodriguez,Mikaël Agopiantz et al.
Nicolas Scheyer et al.
Background: One-carbon metabolism (OCM) and steroid metabolism are fundamental biochemical pathways that regulate essential cellular processes and physiological functions. OCM is involved in DNA synthesis, methylation, an...
Role of melatonin in intestinal mucosal injury induced by chronic restraint stress in mice [0.03%]
慢性束缚应激诱导的小鼠肠黏膜损伤及褪黑素的干预作用
Sun Zhongxin,Chai Lulu,Li Dandan et al.
Sun Zhongxin et al.
Introduction: A growing body of evidence demonstrates that gastrointestinal motility disorder (GIMD) and gastric stress ulcers can be induced by chronic stress, whereas melatonin (MT) elicits anti-inflammatory and antioxi...
Impact of hyperoside on the blood-brain barrier in rats with bacterial meningitis through the microRNA-155/BDNF pathway [0.03%]
檞皮素通过微小核糖核酸-155/脑源性神经营养因子信号通路影响细菌性脑膜炎血脑屏障功能研究
Tao Zhang,Long Zhao,Renzhao Kuang
Tao Zhang
Objective: This study aims to elucidate the effect and mechanism of hyperoside on blood-brain barrier (BBB) damage in bacterial meningitis (BM) by regulating the microRNA-155 (miR-155)/brain-derived neurotrophic factor (B...
Smoking adversely affects survival of metastatic lung carcinoid patients: analysis of a large international audit and prognostic models for metastasis-free survival and overall survival [0.03%]
吸烟会损害肺类癌转移患者的生存率:来自一项大型国际核查和无进展生存期及总生存率预后模型的分析
Amy Clarke,Aimee Cunningham,Alejandro Garcia-Alvarez et al.
Amy Clarke et al.
Introduction: Among neuroendocrine lung cancers, lung carcinoids (LC, further divided into typical [TC] and atypical [AC]) are rare, representing only the 2% of all bronchopulmonary malignancies, and lack prognostic class...