Multicenter Retrospective Study of Efficacy of Systemic Therapy in Patients with Neuroendocrine Tumor Grade 3 (JOSC-2001) [0.03%]
Ⅲ级神经内分泌肿瘤患者系统治疗有效性的多中心回顾性研究(JOSC-2001)
Hiroyuki Okuyama,Taro Shibuki,Naohiro Okano et al.
Hiroyuki Okuyama et al.
Background: Neuroendocrine tumor G3 (NET G3) is a new category introduced in the WHO 2017 classification. Accordingly, evidence regarding chemotherapy for NET G3 is limited. A multicenter, retrospective analysis was perfo...
Gastrointestinal neuroendocrine neoplasms in children and adolescents - data from the German MET studies (1997-2024) [0.03%]
儿童和青少年胃肠神经内分泌肿瘤的数据：来自德国MET研究（1997-2024）
Katharina Karges,Marina Kunstreich,Michael Abele et al.
Katharina Karges et al.
Introduction: Gastrointestinal neuroendocrine neoplasms (GI-NENs) outside the appendix and pancreas are exceptionally rare in children and adolescents. Limited data on presentation, treatment, and outcomes hinder clinical...
Kisspeptin-dependent puberty onset triggered by increased Kiss1 and Pdyn expression in arcuate Tac3 neurons under reduced estrogen negative feedback and sufficient energy balance in female rats [0.03%]
雌性大鼠在雌激素负反馈减弱和能量平衡充分的情况下由下丘脑弓状核Tac3神经元Kiss1和Pdyn表达上调诱发的依赖于Kisspeptin的青春期发动
Mayuko Nagae,Sutisa Majarune,Takuma Kobayashi et al.
Mayuko Nagae et al.
Introduction: The pre-pubertal quiescence of pulsatile gonadotropin-releasing hormone secretion in mammals is considered due to repressed Kiss1 (encoding kisspeptin) expression in kisspeptin/neurokinin B/dynorphin A (KNDy...
Circulating Tumor DNA Profiling Identifies Actionable Mutations as Prognostic Markers in Advanced Neuroendocrine Tumors [0.03%]
循环肿瘤DNA检测确定可操作突变作为晚期神经内分泌肿瘤的预后标志物
Na Zhou,Guofeng Zhao,Yang Gao et al.
Na Zhou et al.
Introduction Neuroendocrine tumors (NETs) are a rare and heterogeneous group of neoplasms with both clinical and genetic diversity. The clinical applicability of molecular profiling using liquid biopsy for identifying actionable drug target...
Expanded Targeted-Exome Sequencing and Functional Validation Improve Molecular Diagnosis and Refine Genotype-Phenotype Correlations in Congenital Hypogonadotropic Hypogonadism [0.03%]
针对靶向外显子组测序和功能验证可提高先天性低促性腺激素性性腺功能减退症的分子诊断并细化基因型表型相关性
Jessica Silva Fausto,Lucas G A Ferreira,Silvia R Correa-Silva et al.
Jessica Silva Fausto et al.
Introduction: Congenital Hypogonadotropic Hypogonadism (CHH) arises from defects in the synthesis, secretion, or action of gonadotropin-releasing hormone (GnRH), resulting in incomplete or absent pubertal development and ...
Causal relationship between plasma liposomes and autoimmune thyroid disease: a Mendelian randomization study [0.03%]
血浆脂质体与自身免疫性甲状腺疾病因果关系的孟德尔随机化研究
Zhao Sun,Yanning Li,Minghui Zhao et al.
Zhao Sun et al.
Background: Autoimmune thyroid disease is an autoimmune disease. Observational studies have shown that individuals with thyroid dysfunction have dyslipidemia. However, it is uncertain whether there is a causal relationshi...
Real-world patient outcomes on the efficacy of lanreotide treatment for neuroendocrine tumors: the influence of BMI, BSA and renal function [0.03%]
兰瑞肽治疗神经内分泌肿瘤的疗效受体重指数、体表面积和肾功能的影响：真实世界研究
Ilse de Weert,Mirjam Crul,Heinz-Josef Klümpen et al.
Ilse de Weert et al.
Background: Lanreotide is an effective and safe first-line therapy to treat patients with a gastro enteropancreatic (GEP) neuroendocrine tumor (NET). Precision oncology may be used to provide each patient with the right d...
Marta Raposo
Marta Raposo
Published Erratum
Neuroendocrinology. 2025 Sep 2:1. DOI:10.1159/000547472 2025
The Causal Role of Gut Microbiota and Immune Cell Mediation in Gastroenteropancreatic Neuroendocrine Neoplasms: A Mendelian Randomization Study [0.03%]
胃肠道微生物群和免疫细胞在胃肠道胰神经内分泌肿瘤中的因果作用：孟德尔随机化研究
Zhichen Jiang,Pengcheng Ma,Fangxia Wang et al.
Zhichen Jiang et al.
Background: Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are a diverse group of tumors arising from neuroendocrine cells, often characterized by slow growth and subtle symptoms, leading to advanced-stage dia...
Lipid Profile Differences in Monomeric Hyperprolactinemia, Macroprolactinemia, and Healthy Controls: A Comparative Analysis [0.03%]
单体高催乳素血症、巨催乳素血症和健康对照的血脂谱差异：一项比较分析
Sami Bahçebaşı,Ferhat Gökay,Yasin Şimşek
Sami Bahçebaşı
Introduction: This study aimed to investigate the effects of different prolactin isoforms - specifically macroprolactin and monomeric prolactin - on lipid metabolism across various subtypes of hyperprolactinemia. ...