Differing ionotropic glutamate receptor gene expression in paraventricular hypothalamic nucleus subregions following angiotensin II hypertension in male mice and female mice with advanced ovarian failure [0.03%]
雄性小鼠和卵巢功能衰退的雌性小鼠在血管紧张素II高血压后下丘脑室旁核亚区的不同离子型谷氨酸受体基因表达
Garrett Sommer,Sumaya Omar Hussein,Teresa A Milner et al.
Garrett Sommer et al.
Introduction: The increased susceptibility to hypertension at menopause is characterized by alterations in brain circuits that regulate cardiovascular homeostasis, however, the mechanisms underlying this association are n...
Stress Hormone Dysregulation in Overweight Male Adults with Obstructive Sleep Apnea [0.03%]
肥胖OSA成人男性的应激激素失调
John Ming Ren Loh,Chung-Wei Lin,Hsin-Ching Lin et al.
John Ming Ren Loh et al.
Introduction: Obstructive sleep apnea (OSA) may influence the hypothalamic-pituitary-adrenal (HPA) axis and result in subsequent physiological dysregulation. Given the inconsistent findings of the current literature and t...
Radiotherapeutic Strategies and Advances in the Management of Pituitary Adenomas [0.03%]
垂体腺瘤的放射治疗策略及最新进展
Neil D Almeida,Jeff F Zhang,Harshini K Cheruvu et al.
Neil D Almeida et al.
Background: Pituitary adenomas are benign brain tumors that develop from hormone-producing cells in the anterior pituitary gland and account for 10-20% of all intracranial tumors. Although typically benign, pituitary aden...
A novel relationship between Corticotropin-releasing hormone level and high-altitude hypoxia in human and rat model [0.03%]
人和大鼠高原缺氧模型脑室下区CRH水平及其与学习记忆损伤的关系
Fan Ping Kong,Gang Xu,Ping Ping Wang et al.
Fan Ping Kong et al.
Background: Acute mountain sickness(AMS) strikes people who travel too quickly to high altitude, outstripping their ability to acclimatize. Individual susceptibility to AMS remains unpredictable. The aim of study was to i...
A Systematic Review of the Effects of N-Methyl-D-Aspartate Receptor Antagonists on Pancreatic Islets [0.03%]
天冬氨酸受体拮抗剂对胰岛影响的系统性研究
Sabrina Wong,Gia Han Le,John Uhlig et al.
Sabrina Wong et al.
Background N-methyl-D-aspartate receptors (NMDARs) are widely distributed in the brain and pancreas. Preliminary evidence indicates that aberrant NMDAR-mediated glutamatergic signaling may disrupt pancreatic islet function and glucose-insul...
PDIA5 and ARFIP1 as Immunogenetic Biomarkers and Therapeutic Targets in Pancreatic Neuroendocrine Neoplasms: A Multi-Omics Study Integrating MR, Gene Expression Microarray, and Single-Cell Transcriptomics [0.03%]
胰腺神经内分泌肿瘤的免疫遗传生物标志物和治疗靶点PDIA5和ARFIP1:整合MR、基因表达微阵列和单细胞转录组学的多组学研究
Huimin Guo,Guiwen Zheng,Shuzhan Yao et al.
Huimin Guo et al.
Introduction: Pancreatic neuroendocrine neoplasms (PanNENs) are characterized by significant clinical heterogeneity and limited therapeutic options, particularly in metastatic or recurrent cases. Identifying actionable mo...
Epidemiology of Neuroendocrine Neoplasia worldwide - A Review of the Literature (2012-2022) [0.03%]
全球神经内分泌肿瘤流行病学文献回顾(2012-2022)
Chinonso A Nwoguh,Marie Line El Asmar,Ayanna Gadsen-Jeffers et al.
Chinonso A Nwoguh et al.
Background The incidence of NENs has been rising globally; However, epidemiological studies on NENs often lack comprehensive geographical comparisons, with limited reporting on demographic variations, risk factors, and tumour site-specific ...
The Clinician's Role in Diagnostic Pathways and the Impact of Clinicopathological Collaboration on Outcomes in Patients with Neuroendocrine Neoplasms: Current Perspectives [0.03%]
神经内分泌肿瘤诊断路径中临床医生的作用及临床病理协作对患者预后影响的当前观点
Alice Laffi,Andrea Lania,Alessandro Zerbi et al.
Alice Laffi et al.
Introduction: Neuroendocrine neoplasms (NENs) classification and diagnosis have substantially advanced, prompting specialization of pathologists and clinicians in NEN fields and fostering close interdisciplinary collabora...