Pharmacogenomics-Guided Precision Therapy for Chronic Kidney Disease with Resistant Hypertension: A Prospective Cohort Study [0.03%]
基于药理基因组学的慢性肾病难治性高血压精确诊疗的前瞻性队列研究
Xiaowen Ha,Xiyuan Gao,Wei Teng et al.
Xiaowen Ha et al.
Objective: Managing blood pressure in patients with chronic kidney disease (CKD) complicated by resistant hypertension (RH) presents significant challenges. The clinical utility of pharmacogenomics (PGx) in this high-risk...
Measurement of skinfold thickness in subscapular area to monitor hydration status in chronic hemodialysis patients [0.03%]
测量肩胛下部皮肤皱褶厚度以监测维持性血液透析患者水化状态
Katarzyna Pęczek-Bartyzel,Piotr Pęczek,Aleksandra Marczyk et al.
Katarzyna Pęczek-Bartyzel et al.
Background Maintaining fluid balance is one of major challenges of the dialysis therapy. It includes, in particular, the management of "dry body mass". We postulated that simple measurement of subscapular skinfold thickness before and after...
Multiple risk factors controlled and mortality risks in chronic kidney disease [0.03%]
多种危险因素控制与慢性肾脏病患者的死亡风险关系研究
Boxuan Pu,Zun Wang
Boxuan Pu
Introduction: Chronic kidney disease (CKD) is associated with elevated mortality risk. The study aimed to investigate the extent to which multiple risk factors controlled could attenuate CKD-related excess mortality. ...
Risk of Orthostatic Hypotension in Chronic Kidney Disease: A Community-Based Cohort Study [0.03%]
基于社区的慢性肾脏病患者体位性低血压患病率及其影响因素流行病学研究
Jong Hoon Seok,Chan Young Park,Seung Yoon Lee et al.
Jong Hoon Seok et al.
Introduction: Patients with chronic kidney disease (CKD) often experience symptoms consistent with orthostatic hypotension (OH); however, not much is known about OH in this population. Therefore, study analyzed OH prevale...
Fabry disease nephropathy. Compendium of "in vitro" and "in vivo" renal effects of globotriaosylsphingosine [0.03%]
法布吕病肾病变：关于三己糖基鞘氨醇“体外”和“体内”肾脏效应综述
Sebastián Pedro Antonio Jaurretche,María Victoria Del Rosal,María Luana Brajkovic et al.
Sebastián Pedro Antonio Jaurretche et al.
Background: Renal damage in Fabry disease (FD) is a consequence of pathological and progressive glycosphingolipids accumulation, which occurs in different magnitudes among FD phenotypes, but is a constant renal tissue phe...
Protein inhibitor of activated STAT 2 (PIAS2) protects against podocyte injury in diabetic nephropathy via inhibiting JAK2/STAT3 pathway [0.03%]
蛋白激活的信号转导子和转录活化子诱导抑制物2(Pias2)通过抑制JAK2/STAT3通路对抗糖尿病肾病中的足细胞损伤
Xia Li,Yanxia Zhang
Xia Li
Background: Diabetic nephropathy (DN) is a common complication in diabetic patients, and the pathological mechanism has not been fully understood. PIAS2, as a counter regulator of the JAK2/STAT3 signaling pathway, may pla...
Inter-relationships of depression with cognitive function and their association with quality of life in older adults with hypertension: national survey findings from a network perspective [0.03%]
基于网络视角的老年人群中抑郁与认知功能的交互作用及其对生活质量影响的横断面调查研究
Hui-Ying Fan,He-Li Sun,Yuan Feng et al.
Hui-Ying Fan et al.
Objectives: Depression and cognitive declines are common and frequently co-occur among older adults with hypertension but their symptom-level relationships are poorly understood. This study explored inter-relationships be...
Differences in urine protein profiles between preterm and full-term infants based on urine proteomic analysis [0.03%]
基于尿蛋白组学分析的早产儿与足月儿尿蛋白图谱差异性研究
Dan Wu,Li Kong,Lulu Zhang et al.
Dan Wu et al.
Background Urine samples could partially reflect the renal condition and could provide possible mechanism of high-risk factor for the long-term development of chronic kidney disease caused by prematurity. Methods Urine samples were collecte...
High serum phosphate promotes cognitive impairment in uremia rats via mediating vascular calcification [0.03%]
高血磷通过介导血管钙化促进尿毒症大鼠认知障碍
Damei Li,Kang Xun,Miao Jia et al.
Damei Li et al.
Introduction: Cognitive impairment (CI) is common in patients with end-stage renal disease (ESRD), but the mechanism of uremia-associated CI is poorly recognized. ...
Amnon Gil,Daniel Kushnir,Victor Frajewicki
Amnon Gil
Introduction Previous studies have found a relative risk of 1.6-2 for renal function deterioration with serum uric acid (UA) level increment. However, the association between the baseline urinary uric acid (UUA) level and renal function dec...