Spheroid-Hydrogel-Integrated Biomimetic System: A New Frontier in Advanced Three-Dimensional Cell Culture Technology [0.03%]
类器官芯片技术及应用研究进展
Seungyeop Yoo,Hyun Jong Lee
Seungyeop Yoo
Background: Despite significant advances in three-dimensional (3D) cell culture technologies, creating accurate in vitro models that faithfully recapitulate complex in vivo environments remains a major challenge in biomed...
Selection of the Most Suitable Culture Medium for Patient-Derived Lung Cancer Organoids [0.03%]
选择适合患者衍生肺癌类器官的最适培养基
Melissa Acosta-Plasencia,Yangyi He,Daniel Martínez et al.
Melissa Acosta-Plasencia et al.
Introduction: Patient-derived organoids have emerged as a promising in vitro model for precision medicine, particularly in cancer, but also in noncancer-related diseases. However, the optimal culture medium for culturing ...
Robust Differentiation of Human Pluripotent Stem Cells into Lymphatic Endothelial Cells Using Transcription Factors [0.03%]
利用转录因子将人多能干细胞 robust 地分化为淋巴内皮细胞
Sanjoy Saha,Francine Graham,James Knopp et al.
Sanjoy Saha et al.
Introduction: Generating new lymphatic vessels has been postulated as an innovative therapeutic strategy for various disease phenotypes, including neurodegenerative diseases, metabolic syndrome, cardiovascular disease, an...
Dilek Cuhalik,Morris Gellisch,Gabriela Morosan-Puopolo et al.
Dilek Cuhalik et al.
Introduction: Basic helix-loop-helix (bHLH) transcription factors are expressed in various organs and are involved in diverse developmental processes. The mouse atonal homolog 8 (Atoh8), a bHLH transcription factor, plays...
Reconsidering Neurogenetic Indication in the Human Brain: Broad Expression of Doublecortin Transcript in the Hippocampal and Cortical Cell Populations [0.03%]
再论人类大脑中的神经遗传标志：海马和皮层细胞群中双皮质素转录子的广泛表达
Tae-Hyeon Cho,Miri Kim,Shin Hyung Kim et al.
Tae-Hyeon Cho et al.
Introduction: Neurogenesis in the adult brain may play an important role in memory and cognition; however, knowledge of neurogenic markers in the human brain remains limited. We compared the single-nucleus transcriptome o...
Development of the Interosseous Muscles of the Human Hand: Morphological and Functional Aspects of the Terminal Insertion [0.03%]
人手间骨肌的发育：末端插入的形态和功能方面
Estela Maldonado,Elena Martínez-Sanz,Javier Catón et al.
Estela Maldonado et al.
Introduction: To date, there have been no studies conducted on the development of interosseous muscles (IO) in the human hand. This study aimed to investigate the development of these muscles in order to clarify their ter...
Three-Dimensional Cell Culture Scaffold Supports Capillary-Like Network Formation by Endothelial Cells Derived from Porcine-Induced Pluripotent Stem Cells [0.03%]
来源于猪诱导多能干细胞的内皮细胞在三维细胞培养支架中形成类毛细血管网络
Yu-Jing Liao,Yi-Shiou Chen,Yu-Ching Lin et al.
Yu-Jing Liao et al.
Introduction: Endothelial cells (EC) can be generated from porcine-induced pluripotent stem cells (piPSC), but poor efficiency in driving EC differentiation hampers their application and efficacy. Additionally, the cultur...
Lack of nuclear localization of the Creb3l1 transcription factor causes defects in caudal fin bifurcation in zebrafish Danio rerio [0.03%]
Creb3l1转录因子核内定位缺陷导致斑马鱼尾鳍分叉异常
Peyton E VanWinkle,Bridge Wynn,Eunjoo Lee et al.
Peyton E VanWinkle et al.
The formation of normal bone and bone healing require the cAMP-responsive element binding protein 3-like-1 (Creb3l1) transmembrane transcription factor, as deletion of the murine CREB3L1 results in osteopenic animals with limited capacity t...
Poly(Lactic-Co-Glycolic Acid) Microparticles for the Delivery of Model Drug Compounds for Applications in Vascular Tissue Engineering [0.03%]
用于血管组织工程的模型药物化合物递送的聚乳酸-co-甘酸微粒
Jordyn M Wyse,Bryan A Sullivan,Priscilla Lopez et al.
Jordyn M Wyse et al.
Introduction: Localized delivery of angiogenesis-promoting factors such as small molecules, nucleic acids, peptides, and proteins to promote the repair and regeneration of damaged tissues remains a challenge in vascular t...
Published Erratum
Cells, tissues, organs. 2024 Jun 20:1. DOI:10.1159/000539752 2024