GAPDH, β-actin, and β-tubulin display age-dependent protein expression changes in the mouse cortex during development [0.03%]
缺氧诱导因子1抑制剂FX-11通过激活凋亡和自噬途径对神经胶质瘤细胞产生抗增殖作用
Daniella Rodriguez,Michelle Nguyen,Tejas Devata et al.
Daniella Rodriguez et al.
GAPDH, β-actin, and β-tubulin are essential housekeeping proteins commonly used as reference controls for protein expression studies. GAPDH is a key glycolytic enzyme that facilitates the production of cellular energy, while β-actin and ...
Eight cases of Pediatric Acute Onset Neuropsychiatric Syndrome (PANS) with Inflammatory Bowel Disease (IBD): Immunologic Intersections [0.03%]
8例具有炎症性肠病的儿童急性起病神经精神综合征(PANS)患者的免疫交叉研究
Angela W Tang,Paula M Prieto Jimenez,Ian K T Miller et al.
Angela W Tang et al.
Introduction: Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) is an immune-mediated disease characterized by abrupt onset neurobehavioral changes. Inflammatory bowel disease (IBD) includes ulcerative colitis (UC) a...
GROWTH DIFFERENTIATION FACTOR 15 KNOCKOUT MICE ARE PROTECTED FROM NEONATAL HYPOXIC-ISCHEMIC INJURY IN A SEX DEPENDENT MANNER [0.03%]
生长分化因子15基因敲除小鼠脑缺氧缺血损伤的保护作用及性别依赖性研究
Jeremy R Herrmann,Patrick M Kochanek,Vincent A Vagni et al.
Jeremy R Herrmann et al.
Introduction: Neuroinflammation plays a critical role in tissue injury and repair after neonatal hypoxic-ischemic (HI) brain injury and varies by sex. Growth differentiation factor-15 (GDF-15) is a cytokine released by ma...
Transferring mouse Emx1 and Emx2 lentiviruses into the chicken embryonic brain and their implication to the organization and evolution of the amniote pallium [0.03%]
鸡胚胎脑中导入小鼠Emx1和Emx2 lentivirus及其对羊膜动物皮层的组织和进化意义的研究
Rui Zhao,Yuanyuan Gao,Chao Xi et al.
Rui Zhao et al.
Introduction: Homeobox genes are highly conserved and play critical roles in brain development. Recently we have found that mammals have an additional fragment of approximately 20 amino acids in Emx1 and a poly-(Ala)6-7 i...
Histone lysine crotonylation associated epigenetic mechanism dynamically regulates prenatal stress induced anxiety-related behaviour in adolescent offspring [0.03%]
组蛋白赖氨酸丁硫基修饰的表观遗传机制动态调节孕期应激诱导的子代焦虑样行为
Karunanithi Sivasangari,Koilmani Emmanuvel Rajan
Karunanithi Sivasangari
Introduction: This study designed to examine whether social/ environmental experiences can induce the epigenetic modification, and influence the associated physiology and behaviour. To test this, we have used social stres...
Heterochronic development of the perception of different types of visual illusions [0.03%]
不同类型视觉错觉感知的异时性发展
Vania Navarrete,Valeria Montiel,Miriam Alarcon et al.
Vania Navarrete et al.
Introduction: The underlying neural and/or perceptual mechanisms of different visual illusions are still unknown; thus, they continue to be the focus of many ongoing studies. Inconsistencies persist in the empirical findi...
Dysregulation of brain cholesterol biosynthetic pathway following hypoxia-ischemia in neonatal mice [0.03%]
新生小鼠缺氧缺血后脑胆固醇生物合成途径失调
Fuxin Lu,Celeste Yen,Chase D Corley et al.
Fuxin Lu et al.
Introduction: Brain cholesterol relies on de novo biosynthesis and is crucial for brain development. Cholesterol synthesis is a complex series of reactions that involves more than twenty enzymes to reach the final product...
Scutellariae Radix Ameliorates Prenatal Stress Induced Anxiety-like and Depression-like Behavior in the Offspring via Reversing HPA Axis Hyperfunction and Ameliorating Neurodevelopmental Dysfunction [0.03%]
胡黄连根改善由母体压力诱导的后代类似焦虑和抑郁的行为通过逆转HPA轴过度功能和改善神经发育障碍
Lixia Li,Wenying Zhang,Congying Sun et al.
Lixia Li et al.
Introduction: This study aimed to explore the impact and mechanism of Scutellariae radix (SR), dried root of Scutellaria baicalensis Georgi of Labiatae, on prenatal stress (PS) induced anxiety-like and depression-like beh...
Ruike Chen,Chen Tian,Keqing Zhu et al.
Ruike Chen et al.
Background: The fetal brain undergoes a dynamic process of development during gestation, marked by well-orchestrated events such as neuronal proliferation, migration, axonal outgrowth, and dendritic arborization, mainly e...
Pubertal- and Stress-Dependent Changes in Cellular Activation and Expression of Excitatory Amino Acid Receptor Subunits in the Paraventricular Nucleus of the Hypothalamus in Male and Female Rats [0.03%]
下丘脑视上核中青春期和压力依赖性变化的细胞活化及兴奋性氨基酸受体亚单位在大鼠(公母)中的表达变迁规律
Catherine Parkin,Juliet Ortiz,Sofia Cruz et al.
Catherine Parkin et al.
Introduction: Pubertal maturation is marked by significant changes in stress-induced hormonal responses mediated by the hypothalamic-pituitary-adrenal (HPA) axis, with prepubertal male and female rats often exhibiting gre...