Identification of Novel Kv1.3 Channel-Interacting Proteins Using Proximity Labelling in T-Cells [0.03%]
使用T细胞邻近标记鉴定新的Kv1.3通道相互作用蛋白
Dilpreet Kour,Christine A Bowen,Upasna Srivastava et al.
Dilpreet Kour et al.
Background/aims: Potassium channels regulate membrane potential, calcium flux, cellular activation and effector functions of adaptive and innate immune cells. The voltage-activated Kv1.3 channel is an important regulator ...
Tumor Destructive Mechanical Impulse (TMI) Treatment of Solid Tumors. Part I: Animal Experiments, Clinical Application and Immunological Abscopal Effect [0.03%]
肿瘤灭能机械脉冲(TMI)治疗实体瘤第一部分：动物实验、临床应用及免疫级联效应
Axel Erich Theuer,Ioannis Thomas,Florian Lang et al.
Axel Erich Theuer et al.
Background/aims: The feasibility and effectiveness of Tumor Destructive Mechanical Impulse (TMI) treatment of solid tumors for standard clinical application is investigated. ...
Knee Joint Response to Mechanical Loading: Bounding Mechanotransduction with Rehabilitation [0.03%]
膝关节对机械载荷的响应：用康复手段界定力学向化学信号的转化机制
Mikołaj Stańczak,Bram Swinnen,Jakub Surmacz et al.
Mikołaj Stańczak et al.
The knee joint is a weight-bearing structure that endures varied mechanical stresses in daily and athletic activities. Its cells convert these stresses into biochemical signals through mechanotransduction, prompting changes essential for jo...
Epistemology of the Origin of Cancer III: Fundamentals of How Metastasis Arises [0.03%]
论癌症起源的元知识第三部分：论转移的发生机制
Björn L D M Brücher,Ijaz S Jamall
Björn L D M Brücher
Metastasis, like carcinogenesis, involves the disruption of homeostasis such that cancer cells travel from the primary tumor to distant parts of the body. Almost all cancer deaths are due to metastatic spread. The prevailing theory of metas...
B Cells at the Crossroads of Cardiovascular and Hematologic Disease: Paving the Way for Novel Immunomodulatory Therapies [0.03%]
处在心血管和血液系统疾病十字路口的B细胞：开启新型免疫调节疗法的新途径
Angeliki Choustoulaki,Soumaya Ben-Aicha,Despina Fotiou et al.
Angeliki Choustoulaki et al.
The interaction between the immune and cardiovascular systems is a growing field of investigation with bidirectional aspects. B cells are modulators of the adaptive and the innate immunity and they orchestrate bone marrow and spleen immune ...
Lydia G Gibson,Elena K DeFilippo,Austin Mahajan et al.
Lydia G Gibson et al.
Impermeability of the ascending limb of the Henle loop for water is traditionally regarded as essential for countercurrent multiplication in the kidney. Similar claims have been made about permeability properties of the collecting duct and ...
SIRPα is An Inhibitory Receptor That Regulates NK Cell Activation and Function [0.03%]
SIRPα是调节NK细胞活化和功能的抑制性受体
Lamin B Cham,Thamer A Hamdan,Hilal Bhat et al.
Lamin B Cham et al.
Background/aims: Signal regulatory protein alpha (SIRPα) is an inhibitory receptor expressed on macrophages and dendritic cells. Recent cancer research studies have reported evidence of upregulation of SIRPα on natural ...
Mast Cell Response to Parasites: from Recognition and Activation to Host Defense Modulation [0.03%]
mast细胞对寄生虫的反应：从识别和活化到调节宿主防御
Paulina Żelechowskaa,Aleksandra Góralczyk-Bińkowskaa
Paulina Żelechowskaa
Parasites represent a diverse and widely distributed group of pathogens that cause diseases with significant global health implications. The interaction between parasite and host is characterized by a high degree of complexity, with both pa...
Characterization and Industrial Application of the Enzyme Papain Through the Use of a Biosensor [0.03%]
基于生物传感器的木瓜蛋白酶的特性分析及工业应用研究
Guilber Vergara Velez,Lorena Daniela Domínguez Brito,Melissa Lisbeth Cerón Erazo et al.
Guilber Vergara Velez et al.
Background/aims: Casein influences coagulation, yield, and product quality. This study aimed to develop and validate a papain (EC 3.4.22.2)-based biosensor to quantify casein in whole milk, evaluating its kinetic behavior...
Association Between DRD4 rs747302 and VNTR Polymorphisms and Drug Addiction in An Iraqi Population [0.03%]
多巴胺受体基因多态性与伊拉克人群中药物依赖的关系研究
Shaymaa A H Kadhim,Ahmed F Neamaa,Yomna I Mahmoud et al.
Shaymaa A H Kadhim et al.
Background/aims: Drug addiction is a neuropsychiatric disorder characterised by compulsive drug-seeking behaviour notwithstanding adverse consequences. This work seeks to address a deficiency in the literature by comparin...