Lnc-ANRIL Protects Against Myocardial Ischemia-Reperfusion Injury by Suppressing Ferroptosis via the miR-7238-3p/GPX4 Axis [0.03%]
长链非编码RNA ANRIL通过miR-7238-3p/GPX4轴抑制铁死亡从而保护心肌免受缺血再灌注损伤
Yijun Liu,Binhua Wu,Yunhao Shao et al.
Yijun Liu et al.
Background/aims: Myocardial infarction remains a leading cause of cardiovascular morbidity and mortality. Although reperfusion therapy restores myocardial blood flow, it can induce myocardial ischemia-reperfusion injury (...
Tingting Zhang,Chunfang Kong,Anna Li et al.
Tingting Zhang et al.
Background/aims: Acute myeloid leukemia (AML) is a devastating hematological malignancy without a definitive cure. 6-Gingerol, a bioactive compound, has shown promise in treating various cancers, yet its impact on AML rem...
3-Acetyl-11-Keto-Beta-Boswellic Acid Inhibits Adipogenesis by Suppressing Autophagy and Inducing AMPK Phosphorylation in 3T3-L1 Cells [0.03%]
3-氧代-11-酮-beta-波斯宁酸通过抑制自噬和诱导AMPK磷酸化抑制3T3-L1细胞的脂肪细胞生成作用
Faizullah Khan,Muhammad Waqas,Hassan Moghtaderi et al.
Faizullah Khan et al.
Background/aims: Adipogenesis involves preadipocyte differentiation and lipid droplet accumulation and is closely linked to obesity. 3-Acetyl-11-keto-beta-boswellic acid (AKBA), a frankincense-derived triterpene, has anti...
Effect of Isobutylparaben and Phenylmercuric Acetate on Juvenile Female Rats with Special Reference to Development, Neurobehavior, and Histopathology [0.03%]
异丁基对苯二酚和醋酸phenylmercuriacetate对雌性幼年大鼠作用的特殊参考：发育，神经行为和组织病理学
Vishwajit B Darekar,Basawarajeshwari Indur
Vishwajit B Darekar
Background/aims: Isobutylparaben (IBP) and phenylmercuric acetate (PMA) are extensively applied in pharmaceuticals, cosmetics, and industrial chemicals, and are of concern for developmental toxicity. This study was conduc...
Allopurinol Attenuates Senescence and Oxidative Stress in Endothelial Cells Exposed to Serum from Hypertensive Patients with Hyperuricemia - a Pilot Study [0.03%]
别嘌呤醇减轻高血压合并高尿酸血症患者血清诱导的内皮细胞衰老和氧化应激-一项初步研究
Katarzyna Lewandowska,Justyna Mikuła-Pietrasik,Krzysztof Książek et al.
Katarzyna Lewandowska et al.
Background/aims: Endothelial cell senescence is a key contributor to the development of vascular pathologies, including arterial hypertension. Uric acid has been shown to promote oxidative stress and inflammation, thereby...
Conifer Essential Oils Modulate Oxidative Stress and Erythrocyte Stability in Human Blood in Vitro [0.03%]
松树精油可调节人体血液的氧化压力及红细胞稳定性能(in vitro)
Halina Tkaczenko,Tomasz Wróblewski,Dzmitryi Ushakou et al.
Halina Tkaczenko et al.
Background/aims: Essential oils (EOs) derived from conifers of the Pinaceae family are complex bioactive mixtures known for their antioxidant and antimicrobial properties. However, their impact on human redox homeostasis,...
Dietary Vitamin E Ameliorate Production Performance Via Pyruvate Metabolism Regulation in An Aged Laying Quails [0.03%]
维生素E通过调节乳酸代谢改善老龄鸡的生产性能
Hongyan Chen,Mengqian Zou,Tingting Cui et al.
Hongyan Chen et al.
Background/aims: This study aimed to clarify the optimal amount of vitamin E required in the late stage of egg laying to explore the aging mechanism of the ovaries in this stage and the regulatory role of vitamin E in fem...
Identifying Circ-RNF216 as a Regulator of Renal Tubular Epithelial Cell Proliferation Via the TGF-Β1/Smad3-Mediated Pathway in Chronic Kidney Disease [0.03%]
圆环RNA-RNF216通过TGF-Β1/Smad3介导的途径调节慢性肾脏病中肾小管上皮细胞增殖
Minghui Xu,Yue Yang,Puhua Zhang et al.
Minghui Xu et al.
Background/aims: Emerging evidence suggests that circular RNAs (circRNAs) play a crucial role in kidney disease regulation. However, their functional significance in chronic kidney disease (CKD) remains poorly understood....
Succinylation of CTBP1 Mediated by SIRT5 Suppresses MAT1A Expression to Promote the Progression of HCC [0.03%]
SIRT5介导的CTBP1琥珀酰化通过抑制MAT1A表达促进肝癌进展
Zhengcai Qiu,Qipeng Wang,Shangshang Li et al.
Zhengcai Qiu et al.
Background/aims: Succinylation, a recently characterized post-translational modification (PTM), is a ubiquitously occurring protein modification implicated in diverse biological processes via regulation of protein functio...