A Comprehensive Pan-Cancer Analysis of the Mitochondrial Uncoupling Protein UCP2, with a Focus on Sex and Gender-Related Aspects [0.03%]
全面的泛癌分析线粒体解偶联蛋白UCP2及其性别相关性方面
Soha Sadeghi,Vanessa Checchetto,Tatiana Varanita
Soha Sadeghi
Background/aims: Mitochondrial uncoupling protein 2 (UCP2) plays a crucial role in regulating oxidative stress and cellular metabolism, positioning it as an important subject in oncological research. The involvement of UC...
Nitric Oxide-Dependent Regulation of Oxygen-Related Processes in a Rat Model of Lead Neurotoxicity: Influence of the Hypoxia Resistance Factor [0.03%]
一氧化氮依赖性调节胎鼠脑铅中毒模型中氧合过程：低氧耐受因子的影响
Natalia Kurhaluk,Piotr Kamiński,Oleksandr Lukash et al.
Natalia Kurhaluk et al.
Background/aims: Lead exposure is known to induce oxidative stress and neurotoxicity. Nitric oxide (NO) plays an important role in modulating oxidative stress, with L-arginine as a precursor of NO and Nω-nitro-L-arginine...
Aleksandra Szustka,Anna Krześlak
Aleksandra Szustka
Breast cancer is the most frequent cancer among women. Despite extensive research in recent years the molecular basis of breast cancer development, growth and metastasis remains unclear. Numerous studies highlight the involvement of BMI-1 i...
The Effectiveness of Physical Exercise in Reducing Common Risk Factors of Atherosclerosis: A Systematic Review [0.03%]
运动对动脉粥样硬化常见危险因素的影响：系统性综述
Nada Alhazmi
Nada Alhazmi
Background/aims: Atherosclerotic cardiovascular disease (ASCVD) or atherosclerosis is a chronic condition that is incurable and a leading contributor to morbidity and mortality. However, it is easy to prevent ASCVD by man...
Environmental Cues Facilitate Maturation and Patterning of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes [0.03%]
环境诱因促进人诱导多能干细胞源性心肌细胞的成熟和模式化
Enrique Coca,Scott Cho,Christopher Kauffman et al.
Enrique Coca et al.
Background/aims: Advances in induced pluripotent stem cell (iPSC) technology allow for reprogramming of adult somatic cells into stem cells from which patient- and disease-specific cardiomyocytes (CMs) can be derived. Yet...
Change in Nfkb/Nrf2/Bax Levels by High Monomeric Polyphenols Berries Extract (HMPBE) in Acute and Chronic Secondary Brain Damage [0.03%]
浆果提取物(HMPBE)对急性或慢性继发性脑损伤小鼠中NFKB/NRF2/BAX水平的影响
Sergio Modafferi,Francesco Molinari,Livia Interdonato et al.
Sergio Modafferi et al.
Background/aims: High Monomeric Polyphenols Berries Extract (HMPBE) is a formula highly rich in polyphenols clinically proven to enhance learning and memory. It is currently used to enhances cognitive performance includin...
Peroxyredoxin 6 Protects RIN-M5F Pancreatic Beta Cells Against Streptozotocin-Induced Senescence [0.03%]
过氧化还原蛋白 6通过保护RIN-M5F胰岛β细胞免受链脲佐菌素诱导的衰老作用发挥抗糖尿病作用
Elena G Novoselova,Olga V Glushkova,Maxim O Khrenov et al.
Elena G Novoselova et al.
Background/aims: There are evidences that a decrease in the functional activity of pancreatic β-cells under type 2 diabetes conditions may be associated with their senescence, therefore, senotherapy may be a prospective ...
GNAS, not a Highly Mutated Gene, Has Prognostic Significance and Carcinogenic Effects in Osteosarcoma [0.03%]
GNAS具有预后价值和致癌作用且并非骨肉瘤中的高频突变基因
Jin Qi,Yanjiao Huang,Yaogang Bian
Jin Qi
Background/aims: Osteosarcoma is a prevalent and aggressive primary malignant bone tumor affecting children and adolescents. Despite advancements in sequencing technologies, there remains a lack of reliable prognostic bio...
Analysis of Erythrocyte Parameters in Multiple and Long-Term Blood Donors from Northern Pomerania (Poland) [0.03%]
波兰波莫瑞地区多次长期献血者红细胞参数分析
Natalia Kurhaluk,Małgorzata Gradziuk,Piotr Kamiński et al.
Natalia Kurhaluk et al.
Background/aims: Assessment of the levels of vital blood parameters in donors is essential to evaluate their health status, ensure their suitability for donation, preserve the integrity of the circulatory system, and faci...