Redefining Parkinson's Disease management: the synergistic role of neurotrophic factors and mitochondria [0.03%]
帕金森病的管理重构：神经营养因子和线粒体的协同作用
Junkai Chang,Zisen Li,Tingting Liu et al.
Junkai Chang et al.
Histone methyltransferase EZH2 drives podocyte injury and senescence in diabetic nephropathy through STAT3 activation [0.03%]
组蛋白甲基转移酶EZH2通过激活STAT3驱动糖尿病肾病中足细胞损伤和衰老
Mengfei He,Lulu Liang,Panpan Zhou et al.
Mengfei He et al.
MYC promotes the progression of prostate cancer by regulating CD47 to induce an immunosuppressive microenvironment [0.03%]
MYC通过调节CD47诱导免疫抑制微环境从而促进前列腺癌进展
Shiyong Xin,Junjie Su,Le Zhao et al.
Shiyong Xin et al.
Tet methylcytosine dioxygenase 2(TET2)-dependent epigenetic regulation in the pathogenesis of polycystic ovary syndrome [0.03%]
Tet甲基胞嘧啶双加氧酶2(TET2)依赖的表观遗传调控在多囊卵巢综合征发病机制中的作用
Kailu Liu,Yanli Hong,Qian Gao et al.
Kailu Liu et al.
Macrophage polarization in inflammatory regulation: molecular mechanisms, therapeutic targets, and translational challenges [0.03%]
炎症调控中的巨噬细胞极化：分子机制、治疗靶点和转化挑战
Wenjie He,Jingwen Xu,Xinyun Li
Wenjie He
Macrophage polarization plays a vital role in regulating inflammation, and the balance of this process is crucial for maintaining tissue health and influencing disease progression. Recent studies have shown how macrophages can adapt their p...
Harnessing the power of the gut microbiome: a review of supplementation diagnosis and therapy for liver cirrhosis [0.03%]
肠道微生态的力量：肝硬化益生补充、诊断与治疗综述
Yuanqing Zhu,Wenkang Gao,Mingjian Cheng et al.
Yuanqing Zhu et al.
Dexras1 plays a crucial role in glucocorticoid-induced osteonecrosis of the femoral head by mediating imbalance between osteogenesis and adipogenesis [0.03%]
Dexras1在糖皮质激素致股骨头坏死中通过介导成骨和脂肪生成失衡发挥关键作用
Yang Liu,Chengqiang Wang,Yizhou Xu et al.
Yang Liu et al.
Emw1/TTC27 is a chaperone required for folding of the eukaryotic elongation factor 2 [0.03%]
EMW1/TTC27是一个参与真核起始因子2折叠的分子伴侣
Mengqi Yang,Ruixin Li,Anna I Mikolajczak et al.
Mengqi Yang et al.
SIRT3 activation protects from nabumetone-induced mitochondrial toxicity in adult human cardiomyocytes [0.03%]
激活的SIRT3通过保护成人人类心肌细胞免受奈布生波林引起的线粒体毒性损伤发挥心脏保护作用
Yafei Huang,Hong Liu,Chao Tong et al.
Yafei Huang et al.
Drug-induced mitochondrial toxicity is a major contributing factor to cardiotoxicity, which can cause drug attrition and adverse cardiac events. To assess the toxicity of anti-inflammatory agents, we used adult human primary cardiomyocytes ...
HAND1 controls the lineage bifurcation of trophoblast and amnion from human pluripotent stem cells [0.03%]
HAND1控制人多能干细胞向合胞体和卵黄囊 fate 命运决定
Changmiao Pang,Qifeng Yang,Yulong Zhong et al.
Changmiao Pang et al.
Trophoblast and amniotic lineages, representing key extra-embryonic tissues, can be differentiated from human pluripotent stem cells (hPSCs) under chemically defined conditions. However, the regulatory mechanisms coordinating the fate decis...