Satoru Saotome,Jiaorong Kuang,Reina Akashi et al.
Satoru Saotome et al.
This paper proposes a new functionalized oligosiloxane as a comonomer for polyester, designed to provide hydrophobic surface properties and enhance low-temperature impact resistance. The functionalization of polymer resin itself has attract...
Synthesis and In Vitro Pharmacological Evaluation of 5,8-Dideaza Analogs of Methotrexate [0.03%]
甲氨蝶呤5,8-二去氨基类似物的合成及其体外药理学评价
Marta Abellán-Flos,Charles Skarbek,Dáire J Gibbons et al.
Marta Abellán-Flos et al.
This study describes the synthesis of a series of dideaza analogs of methotrexate and their preliminary pharmacological and metabolic evaluation. The 5,8-dideazamethotrexate was efficiently obtained in five steps using a new synthetic route...
Understanding Bio-Orthogonal Strain-Driven Sydnone Cycloadditions: Data-Assisted Profiles and the Search for Linear Relationships [0.03%]
生物正交应变驱动sydnone环加成反应的理解：数据辅助谱图及线性关系的研究
Juan García de la Concepción,Pedro Cintas,Rafael Fernando Martínez
Juan García de la Concepción
In the realm of click-type reactions and their application to bioorthogonal chemistry in living organisms, metal-free [3+2] cycloadditions involving mesoionic rings and strained cycloalkynes have gained increasing attention and potentiality...
Synergistic Enhancement of Rhodamine B Adsorption by Coffee Shell Biochar Through High-Temperature Pyrolysis and Water Washing [0.03%]
高温热解和水洗制备的咖啡壳生物炭对罗丹明B的协同吸附增强效应研究
Xurundong Kan,Yao Suo,Bingfei Shi et al.
Xurundong Kan et al.
Biochar-based adsorbents synthesized from agricultural wastes have emerged as economical and environmentally sustainable materials for water purification. In this study, coffee shell-derived biochars were synthesized via pyrolysis at 500 an...
Biotransformations with Photobiocatalysts for Enantioselective Ester Hydrolysis [0.03%]
光生物催化剂的手性酯水解反应研究
Agnieszka Śliżewska,Paulina Majewska,Ewa Żymańczyk-Duda
Agnieszka Śliżewska
This study investigates the efficient and enantioselective hydrolysis of ester bonds through a series of biotransformations employing various photobiocatalysts. A racemic mixture of 1-phenylethyl acetate served as the model substrate. The d...
Synthesis and Characterization of 1-Hydroxy-5-Methyltetrazole and Its Energetic Salts [0.03%]
1-羟基-5-甲基四唑及其性能盐的合成与表征
Lukas J Eberhardt,Maximilian Benz,Jörg Stierstorfer et al.
Lukas J Eberhardt et al.
The objective of this work was the synthesis and characterization of novel, insensitive high explosives. 1-hydroxy-5-methyltetrazole served as both a scaffold and anion for preparing various nitrogen-rich energetic salts. The compounds were...
Synergistic and Antagonistic Mechanisms of Arctium lappa L. Polyphenols on Human Neutrophil Elastase Inhibition: Insights from Molecular Docking and Enzymatic Kinetics [0.03%]
大蓟多酚类化合物对人中性粒细胞弹性蛋白酶抑制的协同和拮抗作用：基于分子对接及酶动力学的见解
Yixun Sun,Mingbo Zhang,Yating Zhang et al.
Yixun Sun et al.
This study systematically investigated the inhibitory mechanism of Arctium lappa L. polyphenols (ALP) against human neutrophil elastase (HNE). Molecular docking techniques were employed to predict the binding patterns and inhibition types b...
Assessment of Harmful Emissions from Multiple Binder Systems in Pilot-Scale Sand Casting [0.03%]
评估生产规模造型用多种粘结剂体系的有害排放物
Erika Garitaonandia,Andoni Ibarra,Angelika Kmita et al.
Erika Garitaonandia et al.
This study investigates hazardous emissions from foundry binder systems, comparing organic resins (phenolic urethane, furan, and alkaline-phenolic) and clay-bonded green sand with inorganic alternatives (sodium silicate and geopolymer). The...
Cochlospermum angolense Welw ex Oliv: Phytochemical Profile, Antioxidant Activity, and Therapeutic Prospects [0.03%]
Cochlospermum angolense Welw ex Oliv：植物化学谱型、抗氧化活性和治疗前景
Nsevolo Samba,Abdy Morales Barrios,Estela Guerrero De León et al.
Nsevolo Samba et al.
The phytochemical investigation and evaluation of the antioxidant activity of the leaves, bark, and roots of Cochlospermum angolense Welw ex Oliv-a valued plant that is widely used in traditional Angolan medicine-hold significant importance...
Antitumor Activity of Isalpinin from Paphiopedilum dianthum on Non-Small Cell Lung Cancer Cell Lines [0.03%]
石斛兰(Isalpinin)对非小细胞肺癌细胞系的抗肿瘤活性
Phisit Pouyfung,Nonthalert Lertnitikul,Hua Bai et al.
Phisit Pouyfung et al.
Lung cancer is a leading cause of cancer-related deaths globally, with current treatments having significant limitations, including drug resistance, metastasis, and tumor heterogeneity. This study investigated the anticancer potential of is...