The Anisotropic Electrothermal Behavior and Deicing Performance of a Self-Healing Epoxy Composite Reinforced with Glass/Carbon Hybrid Fabrics [0.03%]
具有玻璃/碳杂化织物增强的自修复环氧树脂复合材料的各向异性电热行为及除冰性能
Ting Chen,Xusheng Du
Ting Chen
Hybrid fiber-reinforced polymer-laminated composites are often used under icy conditions (such as for reinforcing parts in aircraft frames and bridge beams), where there is an urgent demand for deicing. In this paper, besides the different ...
A Novel HDAC6 Inhibitor Enhances the Efficacy of Paclitaxel Against Ovarian Cancer Cells [0.03%]
一种新型HDAC6抑制剂可增强紫杉醇对卵巢癌细胞的疗效
An-Jui Chi,Jui-Ling Hsu,Yun-Xin Xiao et al.
An-Jui Chi et al.
Ovarian cancer cells overexpress HDAC6, and selective HDAC6 inhibitors have been considered potential new drugs for ovarian cancer either alone or in combination with other anticancer agents. We screened 46 potential novel HDAC6 inhibitors ...
Recent Advances in the Mechanisms and Applications of Astragalus Polysaccharides in Liver Cancer Treatment: An Overview [0.03%]
黄芪多糖抗肝癌作用机制及应用的新进展概述
Wang Wang,Hanting Zhou,Akanksha Sen et al.
Wang Wang et al.
Astragalus polysaccharides (APS), bioactive compounds derived from Astragalus membranaceus, have emerged as promising natural agents in the treatment of hepatocellular carcinoma, a leading cause of cancer-related mortality. Preclinical stud...
Synthesis of Novel 7-Phenyl-2,3-Dihydropyrrolo[2,1- b]Quinazolin-9(1 H)-ones as Cholinesterase Inhibitors Targeting Alzheimer's Disease Through Suzuki-Miyaura Cross-Coupling Reaction [0.03%]
通过Suzuki-Miyaura交叉偶联反应合成新的7-苯基-2,3-二氢吡咯并[2,1-b]喹唑啉-9（1h）-酮作为阿尔茨海默病的胆碱酯酶抑制剂
Davron Turgunov,Lifei Nie,Azizbek Nasrullaev et al.
Davron Turgunov et al.
An important field of research in medicinal and organic chemistry involves halogen-containing heterocyclic synthones, which form the backbone of more complex organic compounds. This study aimed to design and synthesize 28 novel derivatives ...
Molecular Insights into the Interaction of Orexin 1 Receptor Antagonists: A Comprehensive Study Using Classical and Quantum Computational Methods [0.03%]
阿片黑素浓集肽-1受体拮抗剂相互作用的分子机制研究：基于经典和量子计算方法的综合研究
Caio Sena,Pedro Albuquerque,Jonas Oliveira et al.
Caio Sena et al.
Sleep disorders, such as insomnia and narcolepsy, significantly impact quality of life. They are often associated with long-term health consequences, including cardiovascular disease, immune dysfunction, and cognitive impairment. While trad...
Natural-Origin Edible Gels as Delivery Systems for Green Tea Extract: Formulation, Physicochemical, and Biopharmaceutic Profile Assessment [0.03%]
以绿茶提取物为模型药物的天然可食用凝胶给药系统的设计、制备及评价
Andreja Poceviciute,Agne Mazurkeviciute,Lina Raudone
Andreja Poceviciute
Natural-origin edible gels are gaining attention as innovative carriers for bioactive compounds, offering consumer-friendly formats and potential to enhance stability and bioavailability. This study aimed to develop and characterize edible ...
José R A Coelho,Ana Rita F Pacheco,Diogo C Domingues et al.
José R A Coelho et al.
Eugenol-based azo dyes illustrate how bio-sourced compounds like eugenol can be transformed through synthetic processes into functional and colorful compounds. The main purpose of the present work was to develop new responsive colorimetric ...
Solid-Phase Oligosaccharide Synthesis with Highly Complexed Peptidoglycan Fragments [0.03%]
固相寡糖合成复杂肽聚糖片段的研究
Yuichiro Kadonaga,Ning Wang,Atsushi Shimoyama et al.
Yuichiro Kadonaga et al.
Peptidoglycan (PGN) is a component of bacterial cell walls; its fragments are recognized by the cytoplasmic receptors Nod1 and Nod2, thereby promoting the production of inflammatory cytokines and antibodies. To further elucidate these biolo...
Development of an HPTLC-MS Method for the Differentiation of Celosiae Semen: Celosia argentea Versus C. cristata [0.03%]
高效液相色谱-质谱法区分遏藻属种子（夏赀麻籽和顶鸡冠花籽）的方法学研究
Kyu Won Kim,Geonha Park,Sejin Ku et al.
Kyu Won Kim et al.
Celosiae Argentea Semen (CAS), derived from Celosia argentea L., is traditionally used in Korean and Chinese medicine to treat eye disorders and liver heat and is recognized in official Pharmacopeias. In contrast, Celosiae Cristatae Semen (...
Engineered PAM-SPION Nanoclusters for Enhanced Cancer Therapy: Integrating Magnetic Targeting with pH-Responsive Drug Release [0.03%]
用于增强癌症治疗的工程PAM-SPION纳米聚集体：磁性靶向与pH响应型药物释放集成
Dimitra Tzavara,Konstantina Papadia,Argiris Kolokithas-Ntoukas et al.
Dimitra Tzavara et al.
Background: Nanomedicine approaches for cancer therapy face significant challenges, including a poor tumor accumulation, limited therapeutic efficacy, and systemic toxicity. We hypothesized that controlling the clustering...