Rational Design, Synthesis and In Vitro Activity of Diastereomeric Cis-/ Trans-3-Substituted-3,4-Dihydroisocoumarin-4-Carboxylic Acids as Potential Carnitine Acetyltransferase Inhibitors [0.03%]
作为潜在的乙酰基左卡尼转移酶抑制剂的非对映异构体cis-/trans-3取代的-3，4-二氢异香豆素-4-羧酸的设计、合成及体外活性研究
Savina Stoyanova,Milen G Bogdanov
Savina Stoyanova
This study explores a series of 3,4-dihydroisocoumarins as potential inhibitors of fatty acid oxidation through rational design, synthesis and in vitro evaluation. The compounds studied were designed as structural analogs of the natural sub...
Natural Neuroinflammatory Modulators: Therapeutic Potential of Fungi-Derived Compounds in Selected Neurodegenerative Diseases [0.03%]
天然神经炎症调节剂：真菌衍生成分在选定神经退行性疾病治疗中的潜力
Agnieszka Godela,Diana Rogacz,Barbara Pawłowska et al.
Agnieszka Godela et al.
Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis remain incurable. Current therapeutic strategies primarily focus on slowing disease progression, alleviatin...
Harnessing Nature's Chemistry: Deciphering Olive Oil Phenolics for the Control of Invasive Breast Carcinoma [0.03%]
利用自然化学：解析橄榄油酚类化合物以控制侵袭性乳腺癌
Nehal A Ahmed,Abu Bakar Siddique,Afsana Tajmim et al.
Nehal A Ahmed et al.
Breast cancer (BC) is the most common malignancy and the second-leading cause of cancer-related mortalities in women. Epidemiological studies suggested the reduced BC incidence in Mediterranean populations due to the daily consumption of di...
Effects of Polysaccharides Extracted from Stem Barks on the Spontaneous Contractile Activity of the Ileal Smooth Muscle [0.03%]
来源于石南藤茎皮多糖对回肠平滑肌自发收缩活动的影响
Ericka Lorleil Mayindza Ekaghba,Olivier Perruchon,Patrice Lerouge et al.
Ericka Lorleil Mayindza Ekaghba et al.
Decoctions of stem barks from Aucoumea klaineana, Canarium schweinfurthii, Pentadesma butyracea and Scorodophloeus zenkeri are used against affections of irritable bowel syndrome in Gabonese traditional medicine. In the present study, we ai...
Dual-Functional AgNPs/Magnetic Coal Fly Ash Composite for Wastewater Disinfection and Azo Dye Removal [0.03%]
兼具消毒和偶氮染料去除功能的AgNPs/磁性粉煤灰复合材料
Lei Gong,Jiaxin Li,Rui Jin et al.
Lei Gong et al.
In this study, we report the development of a novel magnetized coal fly ash-supported nano-silver composite (AgNPs/MCFA) for dual-functional applications in wastewater treatment: the efficient degradation of methyl orange (MO) dye and broad...
Classical Paal-Knorr Cyclization for Synthesis of Pyrrole-Based Aryl Hydrazones and In Vitro/In Vivo Evaluation on Pharmacological Models of Parkinson's Disease [0.03%]
经典的帕尔-克诺尔环化反应合成吡咯基芳腙及其对帕金森氏病的药理模型的体内外评价研究
Maya Georgieva,Martin Sharkov,Emilio Mateev et al.
Maya Georgieva et al.
Some studies performed in our laboratory on pyrrole and its derivatives pointed towards the enrichment of the evaluations of these promising chemical structures for the potential treatment of neurodegenerative conditions in general and Park...
Degradation of Glyphosate in Water by Electro-Oxidation on Magneli Phase: Application to a Nanofiltration Concentrate [0.03%]
蒙钛型二氧化钛电氧化降解水体中草甘膦的研究及在纳滤浓缩液中的应用研究
Wiyao Maturin Awesso,Ibrahim Tchakala,Sophie Tingry et al.
Wiyao Maturin Awesso et al.
This study evaluates the efficiency of sub-stoichiometric Ti4O7 titanium oxide anodes for the electrochemical degradation of glyphosate, a persistent herbicide classified as a probable carcinogen by the World Health Organization. After opti...
Versatile High-Performance Liquid Chromatography and Ultraviolet Detection-Based Method for the Determination of Thioproline in Pharmaceutical and Cosmetic Products [0.03%]
一种用于药物和化妆品中噻基脯氨酸测定的高效液相色谱-紫外检测法
Marta Gaweł,Martyna Płodzik,Rafał Głowacki et al.
Marta Gaweł et al.
The article presents the first method based on high-performance liquid chromatography and ultraviolet detection (HPLC-UV) for the determination of timonacic (thioproline, 1,3-thiazolidine-4-carboxylic acid, tPro) in pharmaceutical tablets a...
Cathodic Exfoliation of Various Graphite Materials in Potassium Chloride Electrolyte [0.03%]
钾氯化物电解液中各种石墨材料的阴极剥离效应
Md Habibullah Dalal,Nuwan Hegoda Arachchi,Chong-Yong Lee et al.
Md Habibullah Dalal et al.
Cathodic exfoliation of graphite has emerged as an attractive method to synthesize high-quality and lo- defect graphene. Here, it is demonstrated that the type of starting graphite material influences the properties of exfoliated graphene. ...
Unlocking the Fatty Acid and Antioxidant Profile of Grape Pomace: A Systematic Assessment Across Varieties and Vintages for Its Sustainable Valorization [0.03%]
基于品种和年份的葡萄皮渣脂肪酸和抗氧化剂谱系的系统评估及其可持续价值化研究
Teresa Abreu,Rui Ferreira,Paula C Castilho et al.
Teresa Abreu et al.
Grape pomace (GP), the main by-product of the wine industry, represents a valuable source of bioactive metabolites with significant potential for valorization in the context of sustainable bioresource management. This study systematically c...