Trifolirhizin improves the hyperproliferation and excessive inflammatory response in human HaCaT keratinocytes and ameliorates skin lesions in psoriasis-like mouse models [0.03%]
三叶茋苷通过改善表皮过度增殖和炎症反应治疗银屑病研究
Linyu Zhu,Menger Guo,Ling Wang et al.
Linyu Zhu et al.
Keratinocyte hyperproliferation and excessive inflammatory responses are associated with psoriasis pathogenesis. Trifolirhizin has anti-inflammatory and anti-proliferation effects. The purpose of the study was to investigate the role of tri...
Drug-induced pulmonary edema: a real-world pharmacovigilance study using the FDA Adverse Event Reporting System (FAERS) [0.03%]
基于FDA不良事件报告系统(FDA不良事件报告系统（FAERS）的药物所致肺水肿的药物流行病学研究
Zilan Zhong,Manting Liu,Qian Zhong et al.
Zilan Zhong et al.
This study aimed to systematically evaluate the risk of drug-induced pulmonary edema (DIPE) using the Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) database. This retrospective pharmacovigilance study utilized FA...
Pitavastatin reduces intestinal fibrosis in chronic colitis and inhibits colon fibroblast activation by enhancing MMP-9 expression via the IGF-1/IGF-1R pathway [0.03%]
pitavastatin通过IGF-1/IGF-1R信号通路增强MMP-9表达抑制结肠成纤维细胞活化及治疗慢性结肠炎相关肠道纤维化
Mengran Zhang,Hongping Lu,Jun Cheng
Mengran Zhang
Statins have been shown to have antifibrotic effects on various tissues and organs, but their ability to improve chronic colitis-associated intestinal fibrosis and their mechanisms of action remain unclear. The objective of this study was t...
Strength training promotes attenuation of fatty liver while improving insulin resistance and inflammatory biomarkers in obese rats induced by high-fat diet [0.03%]
力量训练可通过改善肥胖脂肪肝诱发大鼠的胰岛素抵抗及炎症生物标志物来减轻脂肪肝病情发展
S Torezani-Sales,A P L Damiani,A R Madureira et al.
S Torezani-Sales et al.
Obesity is an independent risk factor for metabolic dysfunction-associated steatotic liver disease (MASLD). Non-pharmacological strategies, such as strength training (ST), have been investigated for their effectiveness in attenuating MASLD....
Prediction of early myocardial damage in obstructive sleep apnea patients using combined logistic regression and QUEST decision tree models [0.03%]
基于逻辑回归和QUEST决策树模型的阻塞型睡眠呼吸暂停患者早期心肌损伤预测研究
Chong Pei,Zhen Ding,Lei Hu et al.
Chong Pei et al.
Obstructive sleep apnea (OSA) is linked to cardiovascular complications, including myocardial dysfunction, yet early detection remains difficult. This retrospective study aimed to develop a combined logistic regression and QUEST decision tr...
Effect of estradiol valerate on humoral immune function in BALB/c mice after total hysterectomy [0.03%]
戊酸雌二醇对输卵管切除后BALB/c小鼠体液免疫功能的影响
Penghuan Chang,Hui Huang,Peijian Huang et al.
Penghuan Chang et al.
Total hysterectomy is a commonly performed gynecological procedure used to treat uterine pathologies. This study aimed to establish a total hysterectomy mouse model and investigate the effect of estradiol valerate on humoral immune function...
Unveiling immune mechanisms and potential biomarkers in intervertebral disc degeneration through integrated analysis [0.03%]
整合分析揭示椎间盘退变免疫机制及潜在生物标志物
Xuehu Xie,Guoqiang Zhang,Ning Liu
Xuehu Xie
Immune regulation plays an important role in the pathogenesis of intervertebral disc degeneration (IDD). However, the mechanism of immune regulation in IDD is still unclear. All IDD data were downloaded from a public database. The different...
Effects of endurance exercise training on endoplasmic reticulum stress in pancreatic islets of obese mice [0.03%]
有氧运动通过改善内质网应激缓解肥胖小鼠胰岛素抵抗的研究
E Marconato-Júnior,G M Soares,K Rodrigues-Dos-Santos et al.
E Marconato-Júnior et al.
Obesity is a serious health problem worldwide and the search for new control methods and therapies is imperative. Studies indicate that a variety of obesogenic diets may increase the risk of developing type 2 diabetes mellitus (T2D) by caus...
Metals, cardiovascular risk, and the interplay with oxidative stress: a mini-review [0.03%]
金属、心血管风险和氧化应激的相互作用：综述
J G P Pires,I R G Schereider,F W S Cibin et al.
J G P Pires et al.
Oxidative stress plays a key role in the mechanisms underlying pathophysiological processes, such as inflammation, age-related degenerative phenomena, atherosclerosis, hypertension, cancer, diabetes mellitus, neurodegenerative diseases, xen...
RETRACTION: Treatment with β-elemene combined with paclitaxel inhibits growth, migration, and invasion and induces apoptosis of ovarian cancer cells by activation of STAT-NF-κB pathway [0.03%]
撤稿：β- elemene联合紫杉醇通过激活STAT-NF-κB途径抑制卵巢癌细胞生长、迁移、侵袭并诱导其凋亡
[This retracts the article doi: 10.1590/1414-431X20208885].