Unveiling preeclampsia: diagnostic value and potential molecular mechanisms of abnormally methylated immune-related genes [0.03%]
子痫前期异常甲基化免疫相关基因的诊断价值及潜在分子机制探讨
Yuan Yuan,Qin Wang,Xiao Su et al.
Yuan Yuan et al.
Preeclampsia (PE) is a life-threatening obstetric complication, and DNA methylation and immune system disorders play a key role in its development. This study aimed to explore the potential mechanisms and values of abnormally methylated imm...
Metformin attenuates fructose-induced pulmonary fibrosis, possibly through the involvement of the TRPC6 channel [0.03%]
二甲双胍通过瞬时受体电位香草素受体样C通道可能参与介导的机制抑制果糖致肺纤维化作用
B Serez Kaya,O Öner,D Ercetin et al.
B Serez Kaya et al.
Pulmonary fibrosis is a chronic, progressive, fatal lung disease characterized by abnormal lung tissue repair and intense collagen accumulation in the lungs. Despite intensive efforts, no specific treatment has been found. The aim of this s...
Disulfidptosis modification patterns are involved in the immune microenvironment regulation of septic acute respiratory distress syndrome [0.03%]
二硫键修饰模式参与了脓毒症急性呼吸窘迫综合征免疫微环境的调控
Qian Zhang,Junke Ge
Qian Zhang
Disulfidptosis is a new form of programmed cell death. However, there is limited information available regarding the impact of disulfidptosis on septic acute respiratory distress syndrome (ARDS). The 16 disulfidptosis-related genes (DRGs) w...
Effects of combined trunk stretching and lumbar stabilization exercises for chronic non-specific low back pain: a randomized clinical trial [0.03%]
综合躯干拉伸和腰椎稳定性训练对慢性非特异性下背痛的疗效：随机临床试验
C C C Coutinho,D D A Sampaio,N D C Pereira et al.
C C C Coutinho et al.
This study aimed to compare the effectiveness of combining trunk stretching with lumbar segmental stabilization versus exclusively performing lumbar segmental stabilization exercises for treating chronic nonspecific low back pain (CNLBP). T...
Exploring the causal impact of mitochondrial dysfunction on epilepsy: a mendelian randomization study [0.03%]
线粒体功能障碍与癫痫的因果关系研究：孟德尔随机化研究
Lin-Ming Zhang,Fei Wang,Bing-Ran Zhang et al.
Lin-Ming Zhang et al.
Mitochondrial dysfunction contributes critically to epileptogenesis. Therefore, identifying key mitochondrial function-associated genes in epilepsy may provide novel insights into its pathogenesis. We employed expression quantitative trait ...
Therapeutic potential of p-cymene in mitigating alcohol-induced damage in umbilical cord-derived mesenchymal stem cells through restoration of Nanog, VEGF, and antioxidants levels; in silico and in vitro approaches [0.03%]
通过体外和离体方法评估薄荷醇在通过恢复NANOG、VEGF和抗氧化剂水平来减轻酒精引起的来自脐带的间充质干细胞损伤方面的治疗潜力
N Aziz,T Maqbool,M Arooj et al.
N Aziz et al.
Human stem cells can divide and differentiate into various cell types. Umbilical cord-derived mesenchymal stem cells (UC-MSCs) are multipotent cells with high regenerative, anti-inflammatory, and immunomodulatory properties. Ethanol, the ma...
Precision application of target-controlled infusion of esketamine combined with sufentanil in anesthesia for thoracoscopic surgery and its effect on hemodynamics, postoperative pain, and safety [0.03%]
右美托咪啶靶控输注联合舒芬太尼精准应用于胸腔镜手术麻醉的效果及对术后疼痛、血流动力学和安全性的研究
Tianyu Qi,Xiangliu Liu,Sen Liu et al.
Tianyu Qi et al.
We aimed to expound the precise application of target-controlled infusion (TCI) of esketamine combined with sufentanil in anesthesia for video-assisted thoracoscopic surgery (VATS) and its effect on hemodynamics, postoperative pain, and saf...
Drug-related proteinuria: a vigilance analysis based on the FAERS database [0.03%]
基于FAERS数据库的药物相关蛋白尿警戒分析
Zhixiang Mao,Linjian Zhou,Yi Nie et al.
Zhixiang Mao et al.
Proteinuria is a prevalent and significant adverse response (ADR) associated with numerous pharmaceuticals, and we employed the online public FDA Adverse Event Reporting System (FAERS) database to investigate a cohort of medications that ma...
Brief results of heterotopic xenotransplantation of meningioma into the peritoneum of Wistar rats: an experimental study [0.03%]
异种腹腔移植Wistar大鼠绵羊脑膜瘤的实验研究简报
L F M da Silva Junior,M J S Dos Santos,A O do Carmo et al.
L F M da Silva Junior et al.
Meningiomas are the most common primary intracranial tumors, and xenotransplantation models help to study their behavior and test therapies. This research developed a model implanting WHO grade I meningothelial meningioma into the peritoneu...
Sorting nexin 10 knockdown: new strategies for alleviating sepsis-associated acute lung injury [0.03%]
SNX10敲低：治疗脓毒症相关急性肺损伤的新策略
Min Wei,Jian Yang,Zejia Yu et al.
Min Wei et al.
Acute lung injury (ALI) is a common complication of sepsis in connection with excessive inflammation and accumulation of oxidative stress. Sorting nexin 10 (SNX10) is a sorting nexin family member involved in inflammatory processes. This st...