Tracking immune dysregulation in COVID-19: lymphocyte dynamics from hospitalization to recovery [0.03%]
追踪COVID-19中的免疫失调:从住院到恢复的淋巴细胞动态变化
G S Eburneo,M B Sousa,M K C Brunialti et al.
G S Eburneo et al.
A hallmark of COVID-19 patients is the reduction of the lymphocyte population accompanied by activation, senescence, and exhaustion markers. We investigated patients admitted to hospital wards who either recovered after a short hospitalizat...
Detection of autoantibodies in severe COVID-19 patients two years after hospital discharge [0.03%]
重症新冠患者出院两年后自身抗体的检测
E M B Hi,C C R Bianchi,R B Gritte et al.
E M B Hi et al.
After SARS-CoV-2 infection, severe COVID-19 may develop with persistent sequelae, even after hospital discharge. This condition may result from tissue damage or immune alterations caused by the virus, including immune dysregulation, hyperin...
SEMA6A overexpression inhibited tumor growth and metastasis in colorectal cancer [0.03%]
SEMA6A过表达通过抑制CRC细胞的迁移和侵袭而发挥肿瘤抑制作用
Chen Huang,Lihua Ma,Qiufang Zhao et al.
Chen Huang et al.
Colorectal cancer (CRC) is the fourth-leading cause of cancer-related mortality worldwide. Semaphorin 6A (SEMA6A) is a member of the semaphorin family, and its specific biological function in CRC progression remains unclear. Bioinformatics ...
Impact of targeted nursing care and nutritional support on clinical outcomes in diabetic nephropathy patients undergoing maintenance hemodialysis [0.03%]
针对性护理及营养支持在糖尿病肾病维持性血液透析患者中的应用效果分析
Xiufeng Yu,Yaling Li,Xiaoyan Zhang
Xiufeng Yu
This study aimed to investigate the impact of targeted nursing care combined with nutritional support on the clinical outcomes of diabetic nephropathy (DN) patients undergoing maintenance hemodialysis (HD). Clinical indicators such as serum...
Biochanin A exerts an anti-inflammatory effect on adipose tissue and liver of ovariectomized obese mice [0.03%]
生物chanin A对卵巢切除肥胖小鼠的脂肪组织和肝脏的抗炎作用
J M D A Aragão,L Heimfarth,W S Neres et al.
J M D A Aragão et al.
Biochanin A (BCA), a phytoestrogen with broad therapeutic potential, is a promising molecule for alleviating post-menopausal symptoms and treating disorders related to reproductive metabolism. Nevertheless, the effect of BCA on inflammatory...
Retrospective evaluation of the PRE-DELIRIC score in a Chinese mixed ICU: implications for nursing practice [0.03%]
回顾性评价PRE-DELIRIC评分在中国混合型ICU中的应用:对临床护理实践的启示
Tao Yuan,Yu-Xia Wang
Tao Yuan
Delirium is a common complication in intensive care units (ICU). The PRE-DELIRIC model has shown promise in early delirium prediction, but its performance in Chinese ICU settings remains unclear. The objective of this study was to validate ...
H2S inhibits high glucose-induced osteoblast injury by inhibiting ferroptosis in diabetic osteoporosis in vitro [0.03%]
硫化氢通过抑制铁死亡修复高糖所致糖尿病骨质疏松细胞模型中破骨样细胞的损伤
Qingping Shi,Feihong Chen,Wen Wu
Qingping Shi
Diabetic osteoporosis (DOP) is a complication of prolonged hyperglycemia. Hydrogen sulfide (H2S) has been identified as a protective factor in bone development. However, the mechanism by which H2S antagonizes the effects of high glucose (HG...
Difference in the prevalence of hypertension when measured according to the American Heart Association and the European Society of Cardiology hypertension cut-offs in the ELSA-Brasil cohort [0.03%]
采用美国心脏学会和欧洲心脏病学会高血压切点的巴西老龄化与流行病学研究队列中的高血压患病率差异分析
A L F Favaretto,B B Duncan,M I Schmidt et al.
A L F Favaretto et al.
The 2017 US guidelines for the prevention, detection, evaluation, and management of high blood pressure in adults proposed the diagnosis of hypertension at 130/80 mmHg, while the European Society of Cardiology and 2020 Brazilian Guidelines ...
Establishing the reference intervals for subpopulations of T lymphocytes, B lymphocytes, and natural killer cells: insight from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) [0.03%]
源自巴西成人健康纵向研究(ELSA-Brasil)的T淋巴细胞、B淋巴细胞和自然杀伤细胞亚群参考区间的建立:新视野
I C S Dias,C B Maluf,S G Xavier et al.
I C S Dias et al.
The aim of this study was to establish reference intervals for lymphocyte subpopulations in the peripheral blood of Brazilian adults, and to assess potential variations by gender and age groups. The study assessed 351 healthy participants o...
Fractal analysis of peripheral blood neutrophil chromatin in patients infected with Trypanosoma cruzi and/or HIV correlates with left ventricle ejection fraction, T CD4+, and T CD8+ lymphocytes levels [0.03%]
Trypanosoma cruzi和/或HIV感染患者的外周血中性粒细胞染色质的分形分析与左心室射血分数、T_CD4+和T_CD8+淋巴细胞水平相关
N M Silva,G S M Porto,A E Carvalho et al.
N M Silva et al.
Fractal analysis (FA) of neutrophils has demonstrated potential in identifying changes in chromatin associated with clinical parameters in individuals with chronic diseases. Therefore, this study aimed to investigate FA of neutrophils' nucl...