Updated EAACI Statement on Drug Hypersensitivity Skin Testing: Methodology and Non-Irritative Concentrations [0.03%]
EAACI关于药物过敏皮肤试验的更新声明：方法和非刺激浓度
Annick Barbaud,Lene Heise Garvey,Elizabeth Phillips et al.
Annick Barbaud et al.
These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non-immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4-6 weeks post-reaction; whereas beyon...
Placental Epigenetic Alterations and IL-10 Dysregulation Drive Early Persistent Food Allergy [0.03%]
胎盘表观遗传改变和IL-10调节障碍导致早期持续性食物过敏
Eom Ji Choi,Seung Hwa Lee,Si Hyeon Lee et al.
Eom Ji Choi et al.
Background: The mechanisms underlying distinct food allergy (FA) trajectories in children remain unclear. This study aimed to classify FA trajectories and examine differences in placental DNA methylation and serum cytokin...
Factors for Success and Failure of Allergen Immunotherapy (AIT) Trial Design in the Light of Evidence-Based Medicine: Current Aspects 2026 [0.03%]
基于证据的医学视角下过敏免疫治疗(AIT)试验设计成败因素的当前方面(2026年展望)
Roy Gerth van Wijk,Vera Mahler,Melanie Albrecht et al.
Roy Gerth van Wijk et al.
Allergen immunotherapy (AIT) has been acknowledged as the only disease-modifying treatment for respiratory diseases since its introduction in 1911. Although the efficacy and safety have convincingly been established in numerous randomized c...
Review
Allergy. 2026 Aug 18. DOI:10.1111/all.70484 2026
Nomenclature on Immune-Mediated Drug Reactions: An EAACI Position Paper [0.03%]
免疫介导的药物反应命名学：EAACI立场文件
Maria J Torres,Cristobalina Mayorga,Elizabeth J Phillips et al.
Maria J Torres et al.
Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune-mediated drug reactions (IMDRs) represent a small proport...
Gut Microbiota Signatures Reflect Particulate Matter 2.5-Exacerbated Asthma in a Murine Model [0.03%]
基于小鼠模型的颗粒物2.5加重哮喘的肠道菌群标志物研究
Tien-Hsuan Chen,Charles C K Chou,Bor-Luen Chiang
Tien-Hsuan Chen
Pathogenic Airway Bacteria and Local Immune Responses During Early-Life Asthma-Like Episodes [0.03%]
生命早期哮喘样发作时的致病呼吸道细菌及局部免疫反应
Mathilde Bundgaard Svendsen,Tamo Sultan,Anton Kjellberg et al.
Mathilde Bundgaard Svendsen et al.
Background: Respiratory tract colonization by the pathogenic airway bacteria Haemophilus influenzae, Streptococcus pneumoniae, and/or Moraxella catarrhalis has been linked to the pathogenesis of childhood asthma and exace...
Biomarkers Predicting Sustained Unresponsiveness After Oral Immunotherapy in the OPIA Trial [0.03%]
OPIA研究中舌下免疫治疗继发口服免疫治疗后持续无应答的生物标志物预测作用
Duan Ni,Gabriela Pinget,Brigitte Santner-Nanan et al.
Duan Ni et al.
Parental and Healthcare Professional Experiences of Food Allergen Introduction During Complementary Feeding: A Behavioural Theory-Informed Systematic Review [0.03%]
基于行为理论的系统综述：辅食中食物致敏原引入过程中家长和医护人员的体验
Karen Wright,Amelia Dennis,Luise V Marino et al.
Karen Wright et al.
Background: IgE-mediated food allergy burdens individuals, families and healthcare systems. Randomised controlled trials indicate early introduction and regular consumption of common food allergens in infancy can reduce f...
Review
Allergy. 2026 Aug 14. DOI:10.1111/all.70451 2026
How to Train Your Chatbot: Information-Theoretic Foundations of Diagnostic Questioning in Inborn Errors of Immunity [0.03%]
如何训练你的聊天机器人：先天性免疫缺陷诊断问答的信息理论基础
Saul O Lugo Reyes,Estefanía Vásquez Echeverri,Juan Carlos Bustamante Ogando et al.
Saul O Lugo Reyes et al.
Background: Navigating the more than 550 inborn errors of immunity (IEI) requires efficient diagnostic reasoning. Information theory suggests questions should be prioritized by their capacity to reduce diagnostic uncertai...