Molecularly Imprinted Micelles for Fluorescent Sensing of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) [0.03%]
分子印迹胶束的非甾体抗炎药物( NSAIDs )荧光传感器
Likun Duan,Yan Zhao
Likun Duan
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used over-the-counter drugs and their uncontrolled disposal is a significant environmental concern. Although their fluorescent sensing is a desirable method of detection for its sensi...
In situ-forming hyaluronic acid hydrogel through visible light-induced thiol-ene reaction [0.03%]
可见光诱导硫醇-烯点击反应构建透明质酸原位交联水凝胶
Hyun Jong Lee,Gabriella M Fernandes-Cunha,David Myung
Hyun Jong Lee
Here we present hyaluronic acid (HA) hydrogels crosslinked via thiol-ene reaction initiated by visible blue light exposure in the presence of riboflavin phosphate (RFP). The gelation procedure is rapid and proceeds as effectively with expos...
Step-growth Production of Nanogels for Use as Macromers with Dimethacrylate Monomers [0.03%]
逐步合成用作大分子单体的纳米凝胶与双甲基丙烯酸酯单体反应
Guangzhe Gao,Parag K Shah,Tao Liu et al.
Guangzhe Gao et al.
A series of functional nanogels were synthesized by a step-growth mechanism that involved diisocyanate addition to a modest stoichiometric excess of multi-thiols. Nanogels with sizes less than 10 nm were obtained as room temperature liquids...
Tuning Properties of Poly(ethylene glycol)- block-poly(simvastatin) Copolymers Synthesized via Triazabicyclodecene [0.03%]
通过三氮杂双cyclodecene合成的聚（乙二醇）-聚（辛伐他汀）嵌段共聚物的调节性能
Theodora A Asafo-Adjei,Thomas D Dziubla,David A Puleo
Theodora A Asafo-Adjei
Simvastatin was polymerized into copolymers to better control drug loading and release for therapeutic delivery. When using the conventional stannous octoate catalyst in ring-opening polymerization (ROP), reaction temperatures ≥200 °C wer...
Surface modification of a polyethylene film for anticoagulant and anti-microbial catheter [0.03%]
一种新型抗凝和抗菌导管的制备方法及其产品-表面修饰的聚乙烯薄膜导管
Yingying Zheng,Jianjun Miao,Fuming Zhang et al.
Yingying Zheng et al.
A functional anticoagulant and anti-bacterial coating for polyethylene (PE) films is described. The stepwise preparation of this nanocomposite surface coating involves O2 plasma etching of PE film, carbodiimide coupling of cysteamine to the...
Tae-Il Kim,Sung Wan Kim
Tae-Il Kim
Bioreducible polymers, which possess mainly disulfide linkages in the polymer structures, have appeared as ideal gene delivery carriers due to the high stability in extracellular physiological condition and bioreduction-triggered release of...
Polyelectrolyte Nanogels Decorated with Monoclonal Antibody for Targeted Drug Delivery [0.03%]
用于靶向药物输送的单克隆抗体修饰聚电解质纳米凝胶
Nataliya V Nukolova,Zigang Yang,Jong Oh Kim et al.
Nataliya V Nukolova et al.
Novel surface-functionalized cross-linked nanogels were developed as a platform to allow conjugation of monoclonal antibodies (mAb) for targeted drug delivery. Well-defined diblock copolymers of poly(ethylene glycol)-b-poly(methacrylic acid...
Efficient Intracellular Delivery of a Pro-Apoptotic Peptide With A pH-Responsive Carrier [0.03%]
一种带有PH响应型载体的促凋亡多肽的高效胞内传递机制研究
Brian Albarran,Allan S Hoffman,Patrick S Stayton
Brian Albarran
A key challenge in developing protein therapeutics or imaging agents that work against cytosolic targets is the intracellular delivery barrier. Here, we show that the pH-responsive, membrane-destabilizing polymer, poly (propylacrylic acid) ...
Synthesis of Biodegradable Multiblock Copolymers by Click Coupling of RAFT-Generated HeterotelechelicPolyHPMA Conjugates [0.03%]
通过“点击反应”连接RAFT合成的两端不同的聚羟基磷灰石共轭物制备可生物降解的多嵌段共聚物
Jiyuan Yang,Kui Luo,Huaizhong Pan et al.
Jiyuan Yang et al.
A new strategy for the synthesis of biodegradable high molecular weight N-(2-hydroxypropyl)methacrylamide (HPMA)-based polymeric carriers has been designed. An enzyme-sensitive, alkyne-functionalized, chain transfer agent (CTA-GFLG-alkyne; ...
Biguanide-, imine-, and guanidine- based networks as catalysts for transesterification of vegetable oil [0.03%]
基于双胍类、亚胺和胍类的网络催化植物油酯交换反应催化剂
Lev Bromberg,Ezio Fasoli,Michael Alvarez et al.
Lev Bromberg et al.
Polycationic systems based on poly(hexamethylene biguanide) (PHMBG), branched polyethyleneimine (PEI) and poly(N-vinylguanidine) (PVG) have been evaluated as heterogeneous catalysts for the transesterification of sunflower oil by methanol. ...