Characterization of liposarcoma cell lines for preclinical and biological studies [0.03%]
肉瘤细胞系的特征研究用于临床前和生物学研究
Eva W Stratford,Russell Castro,Jeanette Daffinrud et al.
Eva W Stratford et al.
Liposarcoma cell lines represent in vitro models for studying disease mechanisms at the cellular level and for preclinical evaluation of novel drugs. To date there are a limited number of well-characterized models available. In this study, ...
Prognostic Value of Microvessel Density in Tumor and Peritumoral Area as Evaluated by CD31 Protein Expression and Argyrophilic Nucleolar Organizer Region Count in Endothelial Cells in Uterine Leiomyosarcoma [0.03%]
子宫平滑肌肉瘤肿瘤及周缘区微血管密度的预后价值——基于CD31蛋白表达和内皮细胞 argentaffin核仁 organisers计数的评估
Ashot Avdalyan,Igor Bobrov,Vladimir Klimachev et al.
Ashot Avdalyan et al.
The objective of this study was to investigate the prognostic value of microvessel density (MVD) in uterine leiomyosarcoma (LMS) and peritumoral area (PA) as evaluated by CD31 expression and argyrophilic nucleolar organizer region (AgNOR) c...
A M Malhas,V P Sumathi,S L James et al.
A M Malhas et al.
Low-grade central osteosarcoma (LGCO) is a rare variant of osteosarcoma which is difficult to diagnose. If not treated appropriately, the tumour can recur with higher-grade disease. We reviewed our experience of this condition to try and id...
P Blanchette,D Hogg,P Ferguson et al.
P Blanchette et al.
Background. The combination of topotecan and cyclophosphamide (TC) has activity in pediatric patients with recurrent sarcoma, especially Ewing's sarcoma (EWS). We sought to determine the toxicity of and response to TC in adults with recurre...
Assessment of referrals into the soft tissue sarcoma service: evaluation of imaging early in the pathway process [0.03%]
软组织肉瘤服务转诊评估：早期影像学检查在治疗路径中的评价
Emma Rowbotham,Shaheel Bhuva,Harun Gupta et al.
Emma Rowbotham et al.
Purpose. To prospectively evaluate regional referrals into a soft tissue sarcoma service from outside the tertiary centre with local hospital imaging. Materials and Methods. Consecutive referrals were prospectively assessed for: patient dem...
Reliability of Margin Assessment after Surgery for Extremity Soft Tissue Sarcoma: The SSG Experience [0.03%]
肢体软组织肉瘤术后切缘评估可靠性的回顾性研究：SSG经验
Clement S Trovik,Sigmund Skjeldal,Henrik Bauer et al.
Clement S Trovik et al.
Surgery remains the mainstay of soft tissue sarcoma (STS) treatment and has been the primary treatment for the majority of patients in Scandinavia during the last 30 years although the use of adjuvant radiotherapy has increased. Patient and...
Varun Dewan,Anna Darbyshire,Vaiyapuri Sumathi et al.
Varun Dewan et al.
Aim. Our study aimed to determine prognostic factors for survival and recurrence in myxofibrosarcomas based on the experience of a single institution. Methods. Patients who had been diagnosed with a myxofibrosarcoma were identified from our...
Extra-abdominal desmoid tumors associated with familial adenomatous polyposis [0.03%]
与家族性腺瘤性息肉病相关的腹外位_desmoid_肿瘤
George T Calvert,Michael J Monument,Randall W Burt et al.
George T Calvert et al.
Extra-abdominal desmoid tumors are a significant cause of morbidity in patients with familial adenomatous polyposis syndrome. Understanding of the basic biology and natural history of these tumors has increased substantially over the past d...
Juan Martín Liberal,Laura Lagares-Tena,Miguel Sáinz-Jaspeado et al.
Juan Martín Liberal et al.
Sarcomas are a heterogeneous group of mesenchymal malignancies that very often lead to death. Nowadays, chemotherapy is the only available treatment for most sarcomas but there are few active drugs and clinical results still remain very poo...
Osteosarcoma Phenotype Is Inhibited by 3,4-Methylenedioxy-β-nitrostyrene [0.03%]
3,4-亚甲二氧基-β-亚硝基苯乙烯通过抑制糖酵解及谷氨酰胺代谢来逆转骨肉瘤表型
Patrick J Messerschmitt,Ashley N Rettew,Nicholas O Schroeder et al.
Patrick J Messerschmitt et al.
β-nitrostyrene compounds, such as 3,4-methylenedioxy-β-nitrostyrene (MNS), inhibit growth and induce apoptosis in tumor cells, but no reports have investigated their role in osteosarcoma. In this study, human osteosarcoma cell families wi...