The toronto extremity salvage score in unoperated controls: an age, gender, and country comparison [0.03%]
Toronto截肢保肢评分在未手术受试者中的年龄、性别和国家对比研究
Mark Clayer,Simon Doyle,Nicole Sangha et al.
Mark Clayer et al.
The Toronto Extremity Salvage Score (TESS) is widely used for the functional assessment of patients following surgery for musculoskeletal tumours. The aim of this study was to determine if there are gender and/or age-specific changes, unrel...
DNA methylation and gene expression profiling of ewing sarcoma primary tumors reveal genes that are potential targets of epigenetic inactivation [0.03%]
DNA甲基化及ewing肉瘤原发肿瘤的基因表达谱分析发现了一些可能受到表观遗传学失活作用的基因
Nikul Patel,Jennifer Black,Xi Chen et al.
Nikul Patel et al.
The role of aberrant DNA methylation in Ewing sarcoma is not completely understood. The methylation status of 503 genes in 52 formalin-fixed paraffin-embedded EWS tumors and 3 EWS cell lines was compared to human mesenchymal stem cell prima...
Enhanced growth inhibition of osteosarcoma by cytotoxic polymerized liposomal nanoparticles targeting the alcam cell surface receptor [0.03%]
靶向ALCAM细胞表面受体的细胞毒聚合脂质纳米颗粒增强抑制骨肉瘤生长
Noah Federman,Jason Chan,Jon O Nagy et al.
Noah Federman et al.
Osteosarcoma is the most common primary malignancy of bone in children, adolescents, and adults. Despite extensive surgery and adjuvant aggressive high-dose systemic chemotherapy with potentially severe bystander side effects, cure is attai...
Eric J Stanelle,Emily R Christison-Lagay,Emma L Sidebotham et al.
Eric J Stanelle et al.
Purpose. Liposarcoma is extremely rare in the pediatric population. To identify prognostic factors and determine treatment outcomes, we reviewed our institutional experience with pediatric liposarcoma. Methods. We retrospectively reviewed a...
Functional reconstruction of sarcoma defects utilising innervated free flaps [0.03%]
带神经的游离皮瓣的功能重建在肉瘤的修复中的应用
Damien Grinsell,Claudia Di Bella,Peter F M Choong
Damien Grinsell
Soft-tissue reconstruction following preoperative radiotherapy and wide resection of soft tissue sarcoma remains a challenge. Pedicled and free tissue transfers are an essential part of limb sparing surgery. We report 22 cases of sarcoma tr...
A P Molloy,B Hutchinson,G C O&#x;Toole
A P Molloy
Extra-abdominal desmoid lesions, otherwise known as aggressive fibromatosis, are slow-growing benign lesions which may be encountered in clinical practice. Recent controversies exist regarding their optimal treatment. Given their benign nat...
Imaging features of superficial and deep fibromatoses in the adult population [0.03%]
成人表浅和深部纤维瘤病的影像学特征
Eric A Walker,Jonelle M Petscavage,Pamela L Brian et al.
Eric A Walker et al.
The fibromatoses are a group of benign fibroblastic proliferations that vary from benign to intermediate in biological behavior. This article will discuss imaging characteristics and patient demographics of the adult type superficial (fasci...
A systematic review of the recent quality of life studies in adult extremity sarcoma survivors [0.03%]
近年四肢软组织肉瘤幸存者生活质量研究的系统综述
Melissa H Tang,Donald J W Pan,David J Castle et al.
Melissa H Tang et al.
Background. Extremity sarcoma represents a heterogeneous group of rare cancers that carries a relatively high morbidity with regards to physical function. Quality of Life (QoL) as an outcome is an important consideration in this cohort. We ...
Desmoid fibromatosis in pediatric patients: management based on a retrospective analysis of 59 patients and a review of the literature [0.03%]
儿童 Desmoid 瘤的诊断与治疗（附 59 例临床分析及文献复习）
Caroline Oudot,Daniel Orbach,Véronique Minard-Colin et al.
Caroline Oudot et al.
Background. Only limited data are available concerning desmoid tumor in children. Methods. Fifty-nine children and adolescents with desmoid tumor treated in 2 French cancer centers with a very long followup were retrospectively reviewed. Re...
Comparative gene expression profiling of benign and malignant lesions reveals candidate therapeutic compounds for leiomyosarcoma [0.03%]
良恶性病变的比较基因表达谱分析揭示了平滑肌肉瘤的候选治疗药物
Badreddin Edris,Jonathan A Fletcher,Robert B West et al.
Badreddin Edris et al.
Leiomyosarcoma (LMS) is a malignant, soft-tissue tumor for which few effective therapies exist. Previously, we showed that there are three molecular subtypes of LMS. Here, we analyzed genes differentially expressed in each of the three LMS ...