Vivek Subbiah,Pete Anderson
Vivek Subbiah
Refractory and/or recurrent Ewing's sarcoma (EWS) remains a clinical challenge because the disease's resistance to therapy makes it difficult to achieve durable results with standard treatments that include chemotherapy, radiation, and surg...
Ashley A Kowalewski,R Lor Randall,Stephen L Lessnick
Ashley A Kowalewski
Ewing's sarcoma is a highly aggressive pediatric tumor of bone that usually contains the characteristic chromosomal translocation t(11;22)(q24;q12). This translocation encodes the oncogenic fusion protein EWS/FLI, which acts as an aberrant ...
Jojanneke Seinen,Martin Almquist,Emelie Styring et al.
Jojanneke Seinen et al.
Retroperitoneal sarcomas are rare and treatment should optimally be centralized. Despite successful centralization with 90% of the patients referred prior to surgery, delays occur, which led us to assess lead times in a population-based ser...
Pathobiologic markers of the ewing sarcoma family of tumors: state of the art and prediction of behaviour [0.03%]
尤因肉瘤家族肿瘤的病理生物学标志物：现状与行为预测
Alfredo Pinto,Paul Dickman,David Parham
Alfredo Pinto
Over the past three decades, the outcome of Ewing sarcoma family tumor (ESFT) patients who are nonmetastatic at presentation has improved considerably. The prognosis of patients with metastatic disease at the time of diagnosis and recurrenc...
Brendan Prendergast,John B Fiveash,C Parker Gibbs et al.
Brendan Prendergast et al.
Soft-tissue sarcoma (STS) is a histopathologically diverse group of tumors accounting for approximately 10,000 new malignancies in the US each year. The proximal lower extremity is the most common site for STS, accounting for approximately ...
Joshua D Schiffman,Jennifer Wright
Joshua D Schiffman
Ewing's sarcoma (ES) is a rare tumor that is most common in children and young adults. Late effects of ES therapy include second cancers, a tragic outcome for survivors of such a young age. This paper will explore the frequencies and types ...
Therapeutic Antibodies Targeting CSF1 Impede Macrophage Recruitment in a Xenograft Model of Tenosynovial Giant Cell Tumor [0.03%]
针对CSF1的治疗性抗体在腱鞘巨细胞瘤移植瘤模型中阻碍巨噬细胞的募集
Hongwei Cheng,Paul W Clarkson,Dongxia Gao et al.
Hongwei Cheng et al.
Tenosynovial giant cell tumor is a neoplastic disease of joints that can cause severe morbidity. Recurrences are common following local therapy, and no effective medical therapy currently exists. Recent work has demonstrated that all cases ...
Patrick P Lin,Yongxing Wang,Guillermina Lozano
Patrick P Lin
The origin of Ewing's sarcoma is a subject of much debate. Once thought to be derived from primitive neuroectodermal cells, many now believe it to arise from a mesenchymal stem cell (MSC). Expression of the EWS-FLI1 fusion gene in MSCs chan...
Unresectable retiform hemangioendothelioma treated with external beam radiation therapy and chemotherapy: a case report and review of the literature [0.03%]
不可手术切除的血管内皮细胞瘤经外照射及化疗治疗一例并文献复习
Alina Z Hirsh,Weisi Yan,Lihong Wei et al.
Alina Z Hirsh et al.
Retiform hemangioendothelioma (RH) is an infrequently encountered vascular neoplasm of intermediate or borderline malignancy. Treatment of RH is controversial. We present a case of a 44-year-old Asian male presenting with an unresectable RH...
Case Reports
Sarcoma. 2010:2010:756246. DOI:10.1155/2010/756246 2010
''Two-week waits"-are they leading to earlier diagnosis of soft-tissue sarcomas? [0.03%]
"两周等待期"--它们是否导致了软组织肉瘤的更早诊断？
W St J Taylor,R J Grimer,S R Carter et al.
W St J Taylor et al.
Introduction. The ''two-week wait" was established as a potential means of diagnosing malignant tumours earlier. This paper investigated whether these clinics are leading to earlier diagnosis of malignant soft-tissue lumps. Method. We ident...