Autosomal dominant thrombocytopenia associated with the CYCS p.Arg92Gly variant: clinical characterization of an additional family and observation of antiplatelet tolerance [0.03%]
CYCS p.Arg92Gly变异导致的常染色体显性血小板减少症的临床特征及抗血小板药物耐受性的研究
Emad Muhammad,Eveline Shabbad,Alina Kurolap et al.
Emad Muhammad et al.
Thrombocytopenia 4 (THC4) is a rare autosomal dominant inherited thrombocytopenia caused by pathogenic variants in CYCS, the gene encoding cytochrome c. Although CYCS-related thrombocytopenia is well characterized as a mild, non-syndromic q...
The use of light transmission aggregometry for monitoring platelet transfusion response in a small case cohort of Glanzmann thrombasthenia patients: a hypothesis-generating study [0.03%]
一项关于葛兰兹曼血小板功能障碍病的小型病例队列患者的输注血小板疗效监测的光透射凝集法假设生成研究
Karlijn H G Rutten,Olga Tsiamita,Sean Platton et al.
Karlijn H G Rutten et al.
Light transmission aggregometry (LTA) is commonly used to diagnose platelet disorders and has a specific pattern in Glanzmann thrombasthenia (GT). As there is currently no adequate test to assess the efficacy of platelet transfusion, we exp...
Immature platelet fraction as a prognostic marker in patients with pulmonary embolism [0.03%]
不成熟血小板分数在肺栓塞患者中的预后价值
Akiva Brin,Ranel Loutati,Ariella Tvito et al.
Akiva Brin et al.
Introduction: Immature platelet fraction (IPF), a population of young platelets with distinct histological and functional characteristics, is associated with adverse outcomes in several cardiovascular diseases. However, d...
Prediction of bleeding and thromboembolic complications in patients on chronic hemodialysis with the total thrombus-formation analysis system [0.03%]
血液透析患者的出血和血栓栓塞并发症的总血栓形成分析系统预测
Zorica M Dimitrijevic,Svetlana Apostolovic,Danijela D Tasic et al.
Zorica M Dimitrijevic et al.
Patients receiving hemodialysis (HD) are susceptible to bleeding and thrombosis. We assessed whether the T-TAS assay - which measures platelet thrombus formation (PL-AUC) and fibrin-rich thrombus formation (AR-OT) in whole blood under flow ...
Bridging specialties: repurposing platelet drugs prescribed by cardiologists to help infectious disease doctors treat Staphylococcus aureus bacteremia [0.03%]
专科学科之间的桥梁作用：将心脏病专家开具的促进血小板药物重新配给感染病医生用于治疗金黄色葡萄球菌菌血症
Matthew Geriak,Dani Geriak,Victor Nizet et al.
Matthew Geriak et al.
The platelet is the most important cell in the bloodstream in providing endovascular immunity against Staphylococcus aureus bacteremia. Both quantitative and qualitative thrombocytopenia have been associated with increased mortality in pati...
In vitro investigations of the clot formation and resolution properties of cryopreserved platelets [0.03%]
关于玻璃化冷冻血小板凝血功能的体外研究
Lacey Johnson,Christopher Roan,Pearl Lei et al.
Lacey Johnson et al.
While platelets for transfusion are traditionally stored at room temperature (20-24°C), cryopreservation at -80°C is attractive, as it facilitates an extension of the shelf-life from 7 days to several years. Cryopreserved platelets displa...
Novel compound heterozygous ITGA2B mutations in Glanzmann thrombasthenia associated with adolescent osteoporosis [0.03%]
ITGA2B新杂合突变与青春期患者血小板无力症及骨质疏松关联性研究
Yang Zhang,Yujiao Luo,Guangsen Zhang
Yang Zhang
Glanzmann thrombasthenia (GT), caused by defects in integrin αIIbβ3, is characterized by impaired platelet aggregation. While αIIbβ3 dysfunction is well-documented in hematologic pathology, its association with bone metabolism remains c...
Case Reports
Platelets. 2026 Dec;37(1):2612049. DOI:10.1080/09537104.2025.2612049 2026
Assessing mitochondrial function and protein composition in platelet-derived extracellular vesicles [0.03%]
评估血小板衍生的细胞外囊泡中的线粒体功能和蛋白质组成
Vanessa Veilleux,Nicolas Pichaud,Gilles A Robichaud et al.
Vanessa Veilleux et al.
Platelets, traditionally known for their role in hemostasis, also contribute to inflammation, cancer, and intercellular communication through the release of platelet-derived extracellular vesicles (or platelet-derived microparticles; PMPs)....
A new mouse model of thrombopoietin deficiency arising from a spontaneous single base pair mutation [0.03%]
一种由于基因组自发突变导致的促血小板生成素缺陷型小鼠模型
Nan Sophia Han,Emma E Yvanovich,Shenglin Mei et al.
Nan Sophia Han et al.
Thrombopoietin (TPO) is the principal regulator of bone marrow platelet production and plays an important role in maintaining hematopoietic stem and progenitor cells. Predominantly produced in the liver, circulating TPO levels are primarily...
Immune thrombocytopenia triggered by dostarlimab in a patient with endometrial carcinoma: first reported case [0.03%]
一例接受Dostarlimab治疗的子宫内膜癌患者出现免疫性血小板减少症：首报病例
Adolfo Fernández-Sánchez,Pablo García-Jaén,Carlos Puerta-Vázquez et al.
Adolfo Fernández-Sánchez et al.
Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape for various malignancies, but they are associated with a range of immunerelated adverse events, including rare hematological complications. Immune thrombocytopenia...
Case Reports
Platelets. 2026 Dec;37(1):2601056. DOI:10.1080/09537104.2025.2601056 2026