Brain Connectivity of the Cingulate Cortex in Alcohol Use Disorder: Exploring Its Association With Mindfulness [0.03%]
酒精使用障碍中的扣带回脑连接性：探索其与正念之间的关系
Niklaus Denier,Kevin Zahnd,Maria Stein et al.
Niklaus Denier et al.
Alcohol use disorder (AUD) represents a significant challenge in mental health. Severe AUD is characterized by uncontrolled alcohol consumption and is associated with dysregulation in brain circuits responsible for reward, motivation, decis...
PACAP Signalling Network in the Nucleus Accumbens Core Regulates Reinstatement Behaviour in Rat [0.03%]
阿片类药物复吸行为中伏核内PACAP信号网络的作用研究
Samrat Bose,Gregory Simandl,Evan M Hess et al.
Samrat Bose et al.
Cocaine use disorder (CUD) lacks FDA-approved treatments, partly due to the difficulty of creating therapeutics that target behaviour-related neural circuits without disrupting signalling throughout the brain. One promising candidate for ci...
Habitual Drug Intake Is Hard to Change: On the Discussion About Habits and Compulsions in Drug Addiction [0.03%]
毒品摄入习惯难以改变——论药物成瘾中的习惯与强迫行为的讨论
Andreas Heinz,Stefan Gutwinski,Eva Friedel et al.
Andreas Heinz et al.
The Effect and Mechanism of Magnesium Valproate on Methamphetamine-Addicted Rats [0.03%]
镁异戊巴比妥对甲基苯丙胺成瘾大鼠的作用及机制研究
Yuanrong Li,Lixin Wang,Youhui Sun et al.
Yuanrong Li et al.
Valproate may hold promise as a treatment for addiction. However, there are limited studies examining the effects of magnesium valproate (VPA-Mg) on methamphetamine (MA) addiction, and the relevant mechanisms have not been thoroughly discus...
Chronic Intermittent Ethanol and Withdrawal Suppress Evoked and Spontaneous GABA Release Onto Distinct Populations of Basolateral Amygdala Principal Neurons [0.03%]
慢性断断续续的酒精和戒断抑制了向基底外侧杏仁核主细胞群的诱发性和自发性GABA能传递
Michaela E Price,Hailey X Egido-Betancourt,Sarah E Sizer et al.
Michaela E Price et al.
Unique populations of basolateral amygdala (BLA) neurons regulate anxiety and reward through projections targeting downstream regions like the bed nucleus of the stria terminalis (BNST) and nucleus accumbens (NAC). We showed previously that...
Identification of Interleukin-1β in Whole Blood as a Candidate Biomarker for Alcohol Use Disorder Risk Based on AUDIT Scores [0.03%]
基于AUDIT评分识别全血中的白细胞介素-1β作为酒精使用障碍风险候选生物标志物
Irina Balan,Alejandro G Lopez,Thomas Gilmore et al.
Irina Balan et al.
Alcohol use disorder (AUD) is associated with chronic inflammation and immune dysregulation, yet no validated immune-based markers exist to support assessment or monitoring. This study identifies interleukin-1 beta (IL-1β) in whole blood a...
Przemyslaw Mielczarek,Kinga Hartman,Eagle Yi-Kung Huang et al.
Przemyslaw Mielczarek et al.
This study aimed to investigate the role of LVV-hemorphin-7 (LVV-H7) in alcohol dependence. LVV-H7 is a short peptide derived from the cleavage of haemoglobin chains that binds to opioid receptors and plays diverse roles in various physiolo...
The Impact of Different Sports on Reducing Mobile Phone Addiction: A Systematic Review and Network Meta-Analysis [0.03%]
不同运动减少手机依赖的影响：系统评价和网络 meta 分析
Ying Li,Jianhua Zhang,Zhaojun Luo et al.
Ying Li et al.
This study employed network meta-analysis to evaluate the impact of several exercise interventions on mobile phone addiction. The aim is to determine the most effective exercise intervention measures and establish a reference for future int...
Selective Effects of Acutely Administered N-Acetyl-Cysteine in Rodent Models of Nicotine-Conditioned Behaviours [0.03%]
N-乙酰半胱氨酸在尼古丁条件行为实验模型中选择性作用的急性管理研究
Kelsey Stoddart,Michael Davies,Jamie Oughton et al.
Kelsey Stoddart et al.
Chronic nicotine administration leads to neuroadaptations, an important process in nicotine and tobacco dependence for which treatments are limited. The cysteine pro-drug, N-acetyl-cysteine (NAC), is a promising glutamatergic agent that has...
Neural Correlates of Resistance to Gaming Desire Induced by Social Media Content [0.03%]
社交媒体内容诱导的游戏欲望的神经机制及抵抗游戏副本中的神经活动模式
Yuka Fujimoto,Junya Fujino,Daisuke Matsuyoshi et al.
Yuka Fujimoto et al.
The rise of gaming-related content on social media has increased exposure to game-related stimuli, particularly among young people, which may reinforce gaming urges and create difficulties in controlling gaming behaviour. Therefore, underst...