The Predictive Value of Tenascin-C, Neopterin and Pro-Inflammatory Cytokines (IFN-γ, TNF-α, IL-6) in Alcohol Use Disorder Treatment Response [0.03%]
tenascin-c、neopterin和促炎症细胞因子（ifn-γ、tnf-α、il-6）对酒精使用障碍治疗反应预测价值
Guleser Akpinar,Gulsen Sener,Enes Faruk Altunkiliç et al.
Guleser Akpinar et al.
The underlying neurobiological mechanisms of chronic alcohol consumption, particularly neuroinflammation and immune system dysregulation, have been extensively studied in recent years. In this process, the identification of objective biomar...
Observational Study
Addiction biology. 2026 Aug;31(8):e70181. DOI:10.1111/adb.70181 2026
Transcriptional Response to Chronic Long-Access Fentanyl Self-Administration in Rat Habenula and Amygdala [0.03%]
长期反复给药芬太尼后小鼠缰核和杏仁体的转录组学响应研究
Robin Magnard,Daianna Gonzalez-Padilla,Ege A Yalcinbas et al.
Robin Magnard et al.
Fentanyl is a potent synthetic opioid associated with overdose. However, little is known about fentanyl-induced molecular adaptations in the habenula and amygdala, two brain regions implicated in opioid use and withdrawal. We performed bulk...
Effects of Different Exercise Intensities on Internet Addiction in Adolescents and Young Adults: A Systematic Review and Network Meta-Analysis [0.03%]
不同运动强度对青少年和年轻人网络成瘾影响的系统评价和网络 meta 分析
Min Yu,Yuanyuan Chang,Haobo Kang et al.
Min Yu et al.
This study employed a network meta-analysis to evaluate and compare the efficacy of different exercise intensities (light, moderate and vigorous) on internet addiction and related psychological symptoms in adolescents and young adults. We s...
Abuse Potential and Neurotoxic Effects of the Synthetic Cannabinoid 4F-ABUTINACA Self-Administration in Adult Male Rats [0.03%]
合成大麻素4F-ABUTINACA的滥用潜力及神经毒性效应及其在成年雄性大鼠中的自我给药行为研究
Baobao Shi,Huizhen Liu,Manqing Wu et al.
Baobao Shi et al.
4F-ABUTINACA, a fourth-generation synthetic cannabinoid, has been identified in branded herbal smoking mixtures and e-cigarettes seized in China. However, its potential for abuse and its corresponding neurotoxic effects remain poorly unders...
Longitudinal Cognitive Evolution in Alcohol Use Disorder Patients: Role of Inflammation, Time of Abstinence and Apolipoprotein Profile [0.03%]
酒精使用障碍患者的纵向认知演变：炎症、戒酒时间和载脂蛋白谱的作用
Berta Escudero,Ricardo Olmos,Francisco Arias et al.
Berta Escudero et al.
Alcohol use disorder (AUD) is linked to cognitive deficits that can persist even after prolonged abstinence. Research highlighted associations between plasma apolipoproteins and cognition in AUD. This study examines the longitudinal evoluti...
The Interplay Between Sleep Disturbance, Glymphatic Dysfunction and Altered Brain Networks in Internet Gaming Disorder: A Multimodal Neuroimaging Study [0.03%]
睡眠障碍、脑glymphatic功能异常及网络游戏成瘾相关脑网络改变的相互作用机制：一项多模态影像研究
Jiawen Tian,Hui Zhang,Xinyu Wang et al.
Jiawen Tian et al.
Sleep disturbances are common in individuals with Internet gaming disorder (IGD), yet the neurobiological links between poor sleep quality and addictive symptoms remain unclear. The glymphatic system contributes to cerebrospinal fluid-inter...
Abnormal Brain Structural Covariance Networks of Cortical Thickness in Cocaine Use Disorder [0.03%]
脑皮层厚度的异常结构协变网络（ Cocaine Use Disorder）
Linkai Chen,Youling Li,Jie Chen et al.
Linkai Chen et al.
Cocaine use disorder (CUD) is a serious global public health problem, characterized by compulsive drug seeking and impaired cognitive control. Previous studies using voxel-based morphometry (VBM) or surface-based morphometry (SBM) have iden...
The Orexin System Modulates Stress-Induced Alcohol Preference and Reinstatement in Adolescents: Bioinformatics and Experimental Evidence [0.03%]
生物信息学和实验证据表明 orexin 系统可调节应激诱导的青少年酒精偏好和复吸行为
Wenhao He,Aqian Hu,Tianshu Zhao et al.
Wenhao He et al.
Underage drinking has become a global public health concern. One of the major causes of underage drinking is stress. The orexin system has been reported to be involved in both alcohol addiction and stress. However, few studies have examined...
Andreas Heinz,Selin Icoez,Yvonne Treusch et al.
Andreas Heinz et al.
Pavlovian and operant learning mechanisms promote and maintain alcohol intake despite aversive consequences. Here, we review the evidence for drug-associated modifications of basic learning mechanisms during the initiation and maintenance o...