Aluminum, lead and manganese mixture exacerbates oxidative stress, neuroinflammation, and apoptosis via downregulation of Nrf-2/HO-1/BDNF signaling pathway in rats [0.03%]
铝、铅和锰混合物通过下调Nrf-2/HO-1/BDNF信号通路加剧大鼠氧化应激、神经炎症和细胞凋亡
Baridoo Donatus Dooka,Chinna N Orish,Anthonet N Ezejiofor et al.
Baridoo Donatus Dooka et al.
Heavy metals have been reported to induce neurotoxicity associated with neurodegenerative disorders. However, there is a dearth of information on Al, Pb, and Mn mixture exposure on cerebral cortex functions. This study is aimed at evaluatin...
Evaluating Cell-Free Circulatory Mitochondrial DNA as a Comprehensive Biomarker for Stress: Meta-Analysis of Psychological and Physiological Stress Responses [0.03%]
评估细胞外循环线粒体DNA作为压力综合生物标志物：心理和生理应激反应的荟萃分析
Arpan Chattopadhyay,Harshita Tak,Hemanth Naick B
Arpan Chattopadhyay
Background: Mitochondria play a crucial role in cellular processes such as energy metabolism, reactive oxygen species (ROS) generation, and apoptosis. Mitochondrial dysfunction induced by stress has been implicated in var...
Biosensor driven biomarker analysis: pioneering advancements in cancer diagnosis and therapeutic strategies [0.03%]
生物传感器驱动的生物标志物分析：癌症诊断和治疗策略的开创性进展
Gauri Nimhan,Mahavir Narwade,Kavita Gajbhiye
Gauri Nimhan
The likelihood of successful treatment is significantly increased by early cancer detection. Regretfully, a lot of cancers are not discovered until they have progressed and dispersed throughout the body. This demonstrates the pressing need ...
Aqueous Pistacia lentiscus Leaves Extract Protects Against Ethanol-Induced Gastroduodenal Ulcers in Rat [0.03%]
乙醇诱导的大鼠胃肠道溃疡的急性毒性及防治作用实验研究
Yasmina Zahouani,Abdelhafidh Khazri,Samir Touaylia et al.
Yasmina Zahouani et al.
Background and aim: The protective effects of aqueous extract of Pistacia lentiscus leaves (AELPL) against gastric and duodenal ulcers induced by alcohol oral gavage administration in Wistar rats were investigated in this...
Serum ferritin can serve as a biomarker for the prognosis and increased the prognostic predictive value of ISS/RISS in multiple myeloma patients [0.03%]
血清铁蛋白可作为评估多发性骨髓瘤患者预后的生物标志物并增强ISS/RISS对预后预测价值
Mengmeng Dong,Jinna Zhang,Li Yang et al.
Mengmeng Dong et al.
Purpose: Multiple myeloma (MM) is a terminally differentiated plasma cell hematological malignancy. The revised international staging system (RISS) is commonly used in patients with de novo MM, but it has limitations in p...
Integrated bioinformatics approach for the identification and validation of novel biomarkers in ACC progression and prognosis [0.03%]
一种用于识别和验证新的生物标志物以研究副神经节瘤进展和预后的综合生物信息学方法
Tonima Rahman Tuli,Mijan Mia,Ahsan Habib
Tonima Rahman Tuli
Adrenocortical carcinoma (ACC) is a rare and extremely lethal endocrine malignancy emerging from adrenal cortex, characterized by a poor prognosis. This study, performed integrated bioinformatics to elucidate the underlying molecular mechan...
Effect of Waterpipe Smoking and its Cessation on Metabolic Biomarkers and a Novel Biomarker Omentin-1 [0.03%]
水烟吸食及其戒断对代谢生物标志物和新生物标志物网膜素-1的影响
Hiba A Yousif,Mohammed A Hami
Hiba A Yousif
Background and objective: Waterpipe smoking (WPS) has increased globally and may lead to various metabolic disorders. However, its long-term effects and cessation impact on metabolic biomarkers and omentin-1 remain unclea...
A systematic review of first-trimester blood biomarkers associated with preterm prelabor rupture of the fetal membranes [0.03%]
系统回顾与胎膜早破有关的第一 trimester 血液生物标志物
Mille Kirk,Josephine RothEkmann,Martin Overgaard et al.
Mille Kirk et al.
Preterm prelabor rupture of the fetal membranes (PPROM) increases the risk of neonatal mortality and morbidity. The etiology behind the condition is multifactorial but believed to result from an overactivation of inflammatory pathways. This...