A Study on the Prognosis of Patients with Sepsis or Septic Shock Based on Plasma Proenkephalin Levels: A Meta-Analysis [0.03%]
基于血浆前脑肠肽水平的脓毒症或感染性休克患者预后研究的 meta 分析
Shize Yang,Zuxin Zhou,Yongpeng Xie et al.
Shize Yang et al.
Background: Sepsis can induce multiple organ dysfunction, and its complications, such as acute kidney injury, are associated with poor prognoses. Serum pro-enkephalin (pro-ENK), as a stable biomarker, holds potential valu...
Potential time-sensitive biomarkers for the detection of acute mesenteric ischaemia: a systematic review of animal data [0.03%]
潜在的时间敏感性生物标志物用于检测急性肠系膜缺血：系统性回顾动物数据
Alastair Forbes,Kaspar F Bachmann,Karri Kase et al.
Alastair Forbes et al.
Background: Acute mesenteric ischemia (AMI) is difficult to recognize and is often diagnosed late. Currently there are no established biomarkers that can assist in diagnosis or management. The present study was a systemat...
Tissue expression profiles of miR-6809 and miR-4753 in triple-negative breast cancer: Novel biomarkers of early detection and staging [0.03%]
miR-6809和miR-4753在三阴性乳腺癌中的组织表达特征：早期检测与诊断的新生物标志物
Mohamed Taha,Emad Mekhael,Ahmed Abd-Al Aziz
Mohamed Taha
Background: Triple-negative breast cancer (TNBC) remains lethal due to paucity of targetable markers. MicroRNAs are involved in TNBC pathogenesis; however, their clinical translation in TNBC remain limited. We evaluated m...
Louis Agha-Mir-Salim,Elias Grünewald,Felix Balzer et al.
Louis Agha-Mir-Salim et al.
Digital biomarkers-objective, quantifiable physiological and behavioral measures collected through digital tools-enable continuous health assessment and hold promise for precision medicine. With non-communicable diseases (NCDs) being the le...
Quantitative Analysis of murine C-terminal Alpha-1-Antitrypsin Peptides in experimental Sepsis and their Comparison with human Sepsis Peptide Biomarkers [0.03%]
实验性败血症中鼠源性末端α-1抗胰蛋白酶肽的定量分析及其与人类败血症肽类生物标志物的比较
Franziska Scherr,Na Liu,Ikebana Konwar et al.
Franziska Scherr et al.
The levels of alpha-1-antitrypsin (AAT) peptides could be used as prognostic biomarkers in critically ill patients, and peptide treatment has therapeutic efficiency in experimental sepsis. However, the regulation of AAT peptides in M. muscu...
Depression and oxidative stress in pregnancy: a cross-sectional study of trimester-specific changes [0.03%]
妊娠期抑郁症与氧化应激：一项关于孕周特异性变化的横断面研究
Sule Sirin Berk,Kemal Hansu,Ergul Belge Kurutas et al.
Sule Sirin Berk et al.
Background: The scientific community continues to debate the relationship between pregnancy depression and oxidative stress marker changes. The study tracked oxidative stress marker development in pregnant women with depr...
Myocardial Injury Predicts Mortality in Elderly Carbon Monoxide Poisoning: Development and Internal Validation of a Simple Prognostic Model [0.03%]
心肌损伤可预测一氧化碳中毒老年人的预后：简易预后的模型建立及内部验证
Yong Ai Ling,Changsheng Ye,Xianwei Xiong et al.
Yong Ai Ling et al.
Background: Myocardial injury is a serious complication of acute carbon monoxide poisoning in elderly patients, we aimed to evaluate its association with short-term mortality and to develop a simplified prognostic model w...
A Stromal-Centered Single-Cell Landscape Identifies POSTN+ Fibroblasts as a High-Risk Stromal Subset in Hepatocellular Carcinoma [0.03%]
基于单细胞的肿瘤微环境图谱绘制识别出肝癌中预后不良的相关成纤维细胞分子亚群
Yalin Chen,Tingting Liu,Shichao Zhang et al.
Yalin Chen et al.
Hepatocellular carcinoma (HCC) develops within a complex microenvironment in which cancer-associated fibroblasts (CAFs) are abundant, yet their heterogeneity and functional roles remain incompletely understood. Here, we integrated multi-sit...
Systemic Inflammatory Burden at Diagnosis Predicts Survival in Hodgkin Lymphoma: A Comprehensive Evaluation of the Complete Blood Count Score Model [0.03%]
霍奇金淋巴瘤诊断时的全身性炎症负担影响预后：全面评估完整血细胞计数模型评分系统
Salih Sertaç Durusoy,Deniz Mıhçıoğlu,Sema Köse et al.
Salih Sertaç Durusoy et al.
Background: Although systemic inflammation is a well-established prognostic factor in malignancies, composite inflammation-based models remain underexplored in Hodgkin lymphoma (HL). We investigated the prognostic signifi...
Prognostic model for colorectal cancer based on folic acid metabolism-related genes reveals immune landscape [0.03%]
基于叶酸代谢相关基因的结直肠癌预后模型揭示免疫图谱
Lu Bai,Bo Liu
Lu Bai
Background: Colorectal cancer (CRC) is a common malignant tumor with high invasiveness and mortality. Folic acid metabolism-related genes (FAMGs) are critical for DNA synthesis and repair, but their roles in CRC initiatio...