Involvement of Perk and ATF6 Signal Pathways in Indicating Unfolded Protein Response in Patients with Chronic Lymphocytic Leukaemia [0.03%]
PERK和ATF6信号通路在慢性淋巴细胞白血病患者未折叠蛋白反应中的作用
Nergiz Erkut,Merve Kestane,Selim Demir et al.
Nergiz Erkut et al.
Introduction: PERK, ATF6, and IRE1α signalling pathways are unfolded protein response (UPR) signalling pathways. In this study, we evaluated the effect of PERK and ATF6 signalling pathways, which are UPR signalling pathw...
Combined Plasma Levels of A-type-Natriuretic Peptide And Adrenomedullin Are Associated With Appropriate Anti-Arrhythmia Therapy in Patients With an Implantable Cardioverter Defibrillator but no prior Device Therapy [0.03%]
A型利钠肽与肾上腺素医疗 Combined 联合使用有助于植入式心脏转复除颤器接受过治疗但未进行装置治疗的患者的抗心律失常疗法
Farzin Beygui,Vincent Roule,Estelle Gandjbakhch et al.
Farzin Beygui et al.
BackgroundIdentifying patients benefiting from implantable cardioverter defibrillators (ICD) especially when replacing one that has never served may be challenging.ObjectivesWe assessed the association between plasma levels of mid-regional-...
Multidimensional metabolic profiling in carbon monoxide poisoning: acid-base disturbances correlate with neurological severity [0.03%]
一氧化碳中毒的多维度代谢组学特征：酸碱平衡紊乱与神经功能损伤密切相关
Weiguang Wang,Huihua Huang,Xianwei Xiong et al.
Weiguang Wang et al.
Background: Acute carbon monoxide poisoning triggers complex metabolic derangements including acidosis and alkalosis, but their correlation with neurological injury severity remains insufficiently characterized clinically...
Prognostic Value of c-MET Protein Expression in Gastric Cancer Patients: A Systematic Review and Meta-Analysis [0.03%]
胃癌患者c-MET蛋白表达预后价值的系统评价和Meta分析
Qianni Yang,Xiaodong Han
Qianni Yang
Background: The heterogeneous nature of c-MET overexpression in gastric cancer (GC) leads to a lack of consensus on its prognostic significance. Objective...
Markers of apoptosis and cardiac necrosis during the acute phase of catheter ablation using radiofrequency and pulsed-field energy [0.03%]
射频和脉冲场消融急性期凋亡和心肌损伤的标志物变化
Sabri Hassouna,Marek Hozman,Barbora Bacova et al.
Sabri Hassouna et al.
Introduction: The mechanism of cell death during pulsed-field (PFA) ablation seems substantially different from mechanisms using thermal energy sources (e.g., radiofrequency energy, RFA). In human in vivo studies, apoptos...
Peripheral Cytokine Modulation by Anesthetic Agents: A Systematic Review of Neuroprotective and Anti-Inflammatory Effects in Randomised Clinical Trials [0.03%]
麻醉剂的外周细胞因子调节作用：系统性回顾随机对照临床试验中的神经保护和抗炎作用
Sarah Saxena,Luca Marino,Barbara Hammer et al.
Sarah Saxena et al.
Introduction: Perioperative neurocognitive disorders remain a complex and under-diagnosed complication of surgery, linked to increased mortality and reliance on unemployment or disability benefits. Trauma-induced inflamma...
Evaluation of the role of Human Neutrophil Elastase, Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio as Predictive Markers For severity of acute respiratory toxicity Among Patients Admitted to Poison Control Center of Ain Shams University Hospitals [0.03%]
人中性粒细胞弹性蛋白酶、中性粒细胞淋巴细胞比值和血小板淋巴细胞比值在艾因夏胺大学医院中毒控制中心收治的急性呼吸毒性患者病情严重程度预测标志物中的作用评估
Alaa Mohammed,Mona Elkotb,Eglal Elawady et al.
Alaa Mohammed et al.
Background: There are hundreds of xenobiotics that can damage the respiratory system, necessitating mechanical ventilation. Therefore, acute respiratory toxicity may represent a serious condition that can be complicated b...
CYP450 Gene Polymorphisms and the Risk of Taxane-Induced Neurotoxicity in Breast Cancer Patients: A Systematic Review and Meta-Analysis [0.03%]
乳腺癌患者细胞色素P450基因多态性与紫杉类诱导周围神经毒性风险的系统评价和 meta 分析
Nayara Moretti Rozalem,Bárbara de Moura Moreira,Isabella Pimentel Braz et al.
Nayara Moretti Rozalem et al.
Background: Breast cancer (BC) is the most common cancer in women. Taxanes are widely used, but their neurotoxicity affects patients' quality of life. Genetic polymorphisms in CYP450 enzymes influence taxane metabolism, l...
Aluminum, lead and manganese mixture exacerbates oxidative stress, neuroinflammation, and apoptosis via downregulation of Nrf-2/HO-1/BDNF signaling pathway in rats [0.03%]
铝、铅和锰混合物通过下调Nrf-2/HO-1/BDNF信号通路加剧大鼠氧化应激、神经炎症和细胞凋亡
Baridoo Donatus Dooka,Chinna N Orish,Anthonet N Ezejiofor et al.
Baridoo Donatus Dooka et al.
Heavy metals have been reported to induce neurotoxicity associated with neurodegenerative disorders. However, there is a dearth of information on Al, Pb, and Mn mixture exposure on cerebral cortex functions. This study is aimed at evaluatin...