A Novel Composite Biomarker Score for the Identification of Cognitive Impairment in Patients with Heart Failure: A Pilot Study [0.03%]
心力衰竭患者认知障碍识别的新复合生物标志物评分模型：一项初步研究
Christina Hoyer-Kimura,Justin Palmer,Radha Gopalan et al.
Christina Hoyer-Kimura et al.
Background: Among 6.7million Americans with heart failure(HF), 40-60% are estimated to have mild cognitive impairment(MCI) and are at-risk for vascular contributions to cognitive impairment and dementia(VCID). This pilot ...
miR-142-3p as a Candidate Biomarker for Early-Stage Lung Adenocarcinoma: Integrative Bioinformatics Analysis and experimental Validation [0.03%]
基于整合生物信息学分析和实验验证的 miR-142-3p：早期肺腺癌潜在标志物筛查研究
Mozhgan Sheikholeslami,Saeideh Jafarinejad-Farsangi,Hamidreza Soleimanpour Lichaei et al.
Mozhgan Sheikholeslami et al.
Early-stage lung adenocarcinoma (LUAD) diagnosis is a clinical challenge. MicroRNAs (miRNAs) are identified as candidate biomarkers due to their regulatory role in cancer development. In this study, we performed a systematic analysis accord...
Evaluation of the Immunohistochemical Expression of Lipid Peroxidation Marker 4-HNE and Comparison of the Expression in Various Histopathological Grades of Oral Squamous Cell Carcinoma [0.03%]
4-羟基-2-壬烯酸免疫组织化学表达的评估及其在不同病理分级口腔鳞状细胞癌中的比较研究
Khadijah Mohideen,Chandrasekaran Krithika,Nadeem Jeddy et al.
Khadijah Mohideen et al.
Objective: This retrospective immunohistochemical study evaluated the expression of 4-hydroxy-nonenal (4-HNE), a marker of lipid peroxidation, in oral squamous cell carcinoma (OSCC) and compared staining intensities acros...
Evaluation of the serum creatinine to total bilirubin ratio in psoriasis patients treated with biological agents: Significant reduction following IL-17 inhibitor therapy [0.03%]
生物制剂治疗银屑病患者血清肌酐与总胆红素比率的评估：IL-17抑制剂治疗后显著降低
Funda Tamer,Yusuf Can Edek,Emre Guven et al.
Funda Tamer et al.
Introduction: High serum creatinine to total bilirubin ratio has been associated with an increased risk of developing hypertension. We evaluated the effect of biological agents on serum creatinine to total bilirubin ratio...
Circulating miR-27a as a Non-Invasive Diagnostic Biomarker to Differentiate Malignant from Benign Breast Lesions: A Preliminary Study [0.03%]
循环miR-27a作为区分乳腺良恶性病变的无创诊断标志物的初步研究
Maryam Jamal,Shivani Jaswal,Jasbinder Kaur et al.
Maryam Jamal et al.
BackgroundBreast cancer is the most commonly diagnosed cancer among women worldwide, with no single biomarker yet validated for reliable early diagnosis. miRNAs have emerged as potential circulating biomarkers for several diseases. miR-27a ...
Oxidative DNA damage may promote the development of endometriosis by activating telomerase and extending telomere length: a meta-analysis [0.03%]
氧化性DNA损伤可通过激活端粒酶和延长端粒长度来促进子宫内膜异位症的发展：一项荟萃分析
Huanli He,Xiaohui Yang,Kai Wang et al.
Huanli He et al.
Objective: To investigate the associations between oxidative DNA damage biomarkers [levels of 8-hydroxy-2'-deoxyguanosine (8-OHdG), telomere length (TL), human telomerase reverse transcriptase (hTERT), telomerase activity...
Prognostic role of Naples prognostic score in lung cancer: a meta-analysis [0.03%]
那不勒斯肺癌预后评分的预测作用的meta分析研究
Junrong Yang,Hui Li,Liangqin Li et al.
Junrong Yang et al.
Purpose To clarify the association of pretreatment Naples prognostic score (NPS) with long-term survival among lung cancer patients.Methods EMBASE, Web of Science, PubMed and CNKI databases were searched up to April 16, 2024. Primary outcom...
Placenta specific 1: A Novel Marker for Detection of Metastasis in Mouse Model of Breast Cancer [0.03%]
乳腺癌小鼠模型中检测转移的新标志物PLAC1分子
Sadegh Safaei,Masoumeh Dehghan Manshadi,Hannaneh Golshahi et al.
Sadegh Safaei et al.
Background: Placental-specific 1 (Plac1), with no expression in normal tissues, is expressed in different cancers. Therefore, the potential application of Plac1 to detect metastasis was investigated in breast cancer model...
Unveiling the Oncogenic Role and Prognostic Value of ACTL6A in Cancer: A Systematic Review and Meta-Analysis [0.03%]
ACTL6A在癌症中的致癌作用和预后价值的系统评价和meta分析
Soumya Patil,Raushan Kumar Chaudhary,Prakash Patil et al.
Soumya Patil et al.
Background: Actin-like protein 6A (ACTL6A), a subunit of SWI/SNF (SWItch/Sucrose Non-Fermentable) complex has emerged as a key player in cancer progression. Despite growing evidence of its oncogenic potential, a comprehen...
A diagnostic algorithm to evaluate elevated C-reactive protein levels in juvenile systemic lupus erythematosus [0.03%]
评估儿童系统性红斑狼疮C反应蛋白升高的诊断算法
Ezgi Deniz Batu,Seher Sener,Sila Atamyildiz Ucar et al.
Ezgi Deniz Batu et al.
Objective: C-reactive protein (CRP) levels are generally not correlated with systemic lupus erythematosus (SLE) disease activity. We aimed to develop an algorithm to evaluate juvenile SLE (JSLE) patients with elevated CRP...