Cigarette smoke-induced apoptosis via regulation of the miR-122/PTEN/AKT axis in NR8383 cells and rat model of COPD [0.03%]
微小核糖核酸-122调节PTEN/AKT信号轴诱导香烟烟雾所致NR8383细胞及大鼠COPD模型的凋亡
Yang Jiang,Xiaosheng Jin
Yang Jiang
Background: PM2.5-induced COPD lacks effective therapies due to unclear pathogenesis. This study explores the role of miR-122 and PTEN in PM2.5-related COPD. ...
The Role of c-MYC in Gastric Cancer Prognosis: A Kaplan-Meier-Derived Patient Data Meta-Analysis [0.03%]
c-MYC在胃癌预后中的作用：Kaplan-Meier衍生的患者数据meta分析
Francisco Cezar Aquino de Moraes,Gustavo Tadeu Freitas Uchôa Matheus,Larissa Emi Tanimoto et al.
Francisco Cezar Aquino de Moraes et al.
Background Gastric cancer (GC) is the fifth leading cause of cancer-related death worldwide, with a median overall survival of approximately 12 months. The proto-oncogene c-MYC is among the most frequently activated oncogenes, implicated in...
RNF186 as a Prognostic Biomarker and Its Correlation with Immune Cell Infiltration in Clear Cell Renal Cell Carcinoma [0.03%]
泛素连接酶RNF186是预后生物标志物及其与透明细胞肾细胞癌免疫细胞浸润的关系研究
Peng Wu,Xiaolu Zhang,Jia Zou et al.
Peng Wu et al.
Background: Ring finger 186 (RNF186) is implicated in cancer development, but its role in clear cell renal cell carcinoma (ccRCC) remains unclear. Methods...
LSP1 is a prognostic biomarker associated with apoptosis in acute myeloid leukemia [0.03%]
LSP1是一个与急性髓系白血病凋亡相关的预后生物标志物
Chenxing Zhang,Xiaomei Liang,Bangxue Jiang et al.
Chenxing Zhang et al.
Background: The leukocyte-specific protein 1 (LSP1) has been implicated in cancer progression, and this paper aims to reveal the prognostic value and pathogenic role of LSP1 in acute myeloid leukemia (AML). ...
Creatine Kinase and McMahon Score as Predictors for Acute Kidney Injury, Renal Replacement Therapy, and Mortality Associated with Poisoning-Induced Rhabdomyolysis [0.03%]
creatine kinase和McMahan评分在中毒性横纹肌溶解急性肾损伤、肾脏替代治疗及死亡率中的预测价值
Nada A Kamel,Mohy El Masry,Sarah S Mohammed
Nada A Kamel
Poisoned patients presenting with rhabdomyolysis are at a higher risk of Acute Kidney Injury (AKI), and consequently, an increased risk of Renal Replacement Therapy (RRT) and mortality. We aimed to compare the prognostic significance of cre...
Bioinformatics-based screening and experimental validation of biomarkers for the treatment of connective tissue-associated interstitial lung disease with liquorice and dried ginger soup [0.03%]
基于生物信息学的益气疏肺汤治疗连接组织相关间质性肺病靶点及标志物筛选与验证研究
Hui Yuan,Qian Wu,Nan Yu et al.
Hui Yuan et al.
Background: Biomarkers for CTD-ILD diagnosis, treatment response evaluation, and pathogenesis elucidation are lacking. Licorice-dried ginger soup alleviates lung injury, but its mechanism is unknown. This study aimed to i...
Sub-Chronic Toxicity of chemically synthesized CuO-NPs in Albino Mice [0.03%]
化学合成的CuO-NPs在白色实验小鼠中的亚慢性毒性研究
Muhammad Waseem Aslam,Ali Umar,Muhammad Saleem Khan et al.
Muhammad Waseem Aslam et al.
The current study explores the synthesis, characterization and toxicity of copper oxides (CuO-NPs) in albino mice. The nanoparticles exhibited a porous, rough-surfaced, spherical morphology; XRD confirmed their crystalline nature, while FTI...
Impact of Pesticide Exposure on Base Excision Repair Gene Polymorphisms in the Haryana Population [0.03%]
农药暴露对哈里亚纳邦人群碱基切除修复基因多态性的影响研究
Heena Gulia,Jagphool Singh,Soniya Jangra et al.
Heena Gulia et al.
Base excision repair (BER) plays a vital role in repairing DNA damage; however, polymorphisms in BER genes may influence an individual's susceptibility to disease risk. We investigated the role of BER genes as a biomarker of susceptibility ...
Emerging Biomarkers in Breast Cancer: Translational and Multi-Omics Perspectives in Precision Oncology [0.03%]
乳腺癌的新兴生物标志物：精准肿瘤学中的转化和多组学视角
Azra Yasmin,Ritesh Jha,Aarti Passi et al.
Azra Yasmin et al.
Breast cancer remains a leading cause of cancer-related mortality among women worldwide, emphasizing the urgent need for improved diagnostic and therapeutic strategies. This review comprehensively explores the emerging landscape of breast c...
A comprehensive review of new potential biomarkers in the detection of chronic kidney disease [0.03%]
慢性肾脏病检测中潜在生物标志物的研究进展综述
Sapna,Pankaj Kumar,Bipul Kalita et al.
Sapna et al.
Introduction: Chronic kidney disease (CKD) typically shows no symptoms in its initial stages. A quick diagnosis (stages 1-3) can change the course of CKD and lessen its effects. Significant kidney damage becomes apparent ...