In vitro Assay for Screening of Optimal Targets for Antigen-Delivery to Murine Dendritic Cells [0.03%]
用于筛选小鼠树突状细胞抗原递呈最佳靶点的体外试验
L H Pugholm,K Varming,R Agger
L H Pugholm
Targeting of antigen to dendritic cells (DCs) increase the efficiency of immunization procedures and may facilitate the development of more effective vaccines. Several surface molecules on DCs have shown to be useful for antigen targeting, ...
Xylaria hypoxylon Lectin as Adjuvant Elicited Tfh Cell Responses [0.03%]
Xylaria hypoxylon凝集素通过诱导Tfh细胞反应发挥辅助型免疫刺激作用
J Kang,Y Zuo,Q Guo et al.
J Kang et al.
Foot-and-mouth disease (FMD) caused by FMD virus (FMDV) is a major health and economic problem in the farming industry. Vaccination of livestock against this highly infectious viral disease is crucial, and inactivated FMD vaccine has been e...
Upregulation of HO-1 with Haemin Alleviates LPS-Stimulated Pro-inflammatory Responses Through Downregulation of p38 Signalling Pathways in Rat Liver [0.03%]
血红素上调HO-1通过下调p38信号途径缓解大鼠肝脏LPS刺激的促炎症反应
J Tang,L Li,C-M Li et al.
J Tang et al.
Haem oxygenase-1 (HO-1) plays an important role in inflammatory disease development and progression. Whether it has an anti-inflammatory role in lipopolysaccharide (LPS)-induced liver injury remains unclear. To investigate the functional ro...
Immunization with Single Oral Dose of Alginate-Encapsulated BCG Elicits Effective and Long-Lasting Mucosal Immune Responses [0.03%]
单次口服藻酸盐包封卡介苗可有效诱导持久的粘膜免疫反应
M Hosseini,F Dobakhti,S R Pakzad et al.
M Hosseini et al.
Effective vaccination against pathogens, which enter the body through mucosal surfaces, requires the induction of both mucosal and systemic immune responses. Here, mucosal as well as systemic immune responses in the lung and spleen of BALB/...
Tumour, Oxidative Stress and Host T Cell Response: Cementing the Dominance [0.03%]
肿瘤、氧化应激与宿主T细胞反应：巩固优势地位
S Bhattacharyya,J Saha
S Bhattacharyya
Reactive oxygen species (ROS) and free radicals are produced intrinsically during normal cellular metabolic processes or extrinsically due to ionizing radiations, UV rays, xenobiotic insult, etc. ROS are important signal mediators and are u...
Food-Nonfood Discrimination in Ancestral Vertebrates: Gamete Cannibalism and the Origin of the Adaptive Immune System [0.03%]
古兽类的食物与非食物辨别机制：生殖细胞的自我异己识别与适应性免疫系统的起源
D Corcos
D Corcos
Adaptive immunity is a complex system that appeared twice in vertebrates (in gnathostomes and in jawless fish) although it is not required for invertebrate defence. The adaptive immune system is tightly associated with self-non-self discrim...
Tissue Distribution Dynamics of Human NK Cells Inferred from Peripheral Blood Depletion Kinetics after Sphingosine-1-Phosphate Receptor Blockade [0.03%]
人NK细胞的组织分布动力学来源于S1P受体阻断后的外周血耗竭动力学推理
M Mehling,A-V Burgener,V Brinkmann et al.
M Mehling et al.
Human natural killer (NK) cell subsets differentially distribute throughout the organism. While CD56(dim) and CD56(bright) NK cell subsets similarly reside in the bone marrow (BM), the CD56(dim) population predominantly accumulates in non-l...
Dear Readers of Scandinavian Journal of Immunology and ECI2015 Attendees [0.03%]
亲爱的《斯堪的纳维亚免疫学杂志》读者和ECI2015参会者
R Jonsson,H-G Ljunggren
R Jonsson
D Wang,F Cai,J Ge et al.
D Wang et al.
We aimed to give a systematic hypothesis on the functions of exercise on circulating monocytes by identifying a discrete set of genes in circulating monocytes that were altered by exercise. The microarray expression profile of GSE51835 was ...
Major Histocompatibility Complex Class II Dextramers: New Tools for the Detection of antigen-Specific, CD4 T Cells in Basic and Clinical Research [0.03%]
主要组织相容性复合体II类葡聚糖衍生物：在基础和临床研究中检测抗原特异性CD4T细胞的新工具
C Massilamany,B Krishnan,J Reddy
C Massilamany
The advent of major histocompatibility complex (MHC) tetramer technology has been a major contribution to T cell immunology, because tetramer reagents permit detection of antigen-specific T cells at the single-cell level in heterogeneous po...