DFS70 Autoantibodies are Rare in Healthy Danish Individuals but may Still Serve as a Diagnostic Aid [0.03%]
丹麦健康人群中的DFS70自身抗体少见但仍可作为诊断辅助标志物
A C Nilsson,A Voss,S T Lillevang
A C Nilsson
Enhanced Humoral Responses Induced by Targeting of Antigen to Murine Dendritic Cells [0.03%]
靶向递呈抗原增强树突状细胞的体液免疫应答
L H Pugholm,L R Petersen,E K L Søndergaard et al.
L H Pugholm et al.
Dendritic cells (DCs) are superior in their ability to induce and control adaptive immune responses. These qualities have motivated the hypothesis that targeted delivery of antigen to DCs in vivo may be an effective way of enhancing immuniz...
The Plasma Level of Proprotein Convertase FURIN in Patients with Suspected Infection in the Emergency Room: A Prospective Cohort Study [0.03%]
急诊疑似感染患者血浆蛋白酶FURIN水平的变化：前瞻性队列研究
N Ranta,H Turpeinen,A Oksanen et al.
N Ranta et al.
There is an increasing need for novel biomarkers that enable better diagnostic and prognostic stratification of patients with suspected infection. A proprotein convertase enzyme FURIN is upregulated upon immune cell activation, and it promo...
Upregulation of Soluble HLA-G5 and HLA-G6 Isoforms in the Milder Histopathological Stages of Helicobacter pylori Infection: A Role for Subverting Immune Responses? [0.03%]
幽门螺杆菌感染较轻的病理阶段溶型HLA-G5和HLA-G6等位基因上调：规避免疫反应的作用？
D M B Oliveira Souza,J Genre,T G Alves Silva et al.
D M B Oliveira Souza et al.
The subversion mechanisms employed by Helicobacter pylori (H. pylori) to escape from immune surveillance and to establish persistent infection are poorly understood. Growing evidence indicates that expression of HLA-G, a non-classical major...
A Review on the Potential Role of Basement Membrane Laminin in the Pathogenesis of Psoriasis [0.03%]
基底膜层粘连蛋白在银屑病发病机制中的潜在作用综述
J P McFadden,I Kimber
J P McFadden
We have previously reviewed alterations to basement membrane laminin in psoriasis and how disruption of this layer could lead to at least some of the pathological changes observed. We here postulate that basement membrane laminin is the key...
The Uptake of Extracellular Vesicles is Affected by the Differentiation Status of Myeloid Cells [0.03%]
髓系细胞的分化状态影响外泌体的摄取
L Czernek,A Chworos,M Duechler
L Czernek
Intercellular communication includes the exchange of various membrane vesicles including exosomes. Exosomes are intraluminal nanovesicles generated from multivesicular bodies, a late endosomal compartment. Cancer cells release exosomes that...
Epstein-Barr virus-driven B Cell Proliferation with CD4+ T Cell Expansion: A Lymphomatoid Granulomatosis-like Disease Related to Hyperinterleukin-10 Secretion of Remarkably Favourable Outcome with Rituximab [0.03%]
EB病毒驱动的B细胞增殖伴CD4⁺T细胞扩增：与高分泌IL-10型淋巴组织增生性疾病利妥昔单抗治疗效果显著的疾病
P Cervera,A Guihot,G Gorochov et al.
P Cervera et al.
Granulomatous lymphomatosis is an Epstein-Barr virus (EBV)-driven B cell proliferation associated with an exuberant CD4(+) T cell reaction with usually histopathological pictures of angiocentrism. So far, the characteristics of CD4(+) T cel...
Mannan Derivatives Instruct Dendritic Cells to Induce Th1/Th2 Cells Polarization via Differential Mitogen-Activated Protein Kinase Activation [0.03%]
甘露糖衍生物通过不同的丝裂原活化蛋白激酶激活诱导树突状细胞使Th1/Th2细胞极化
C Tong,Z Cui,X Sun et al.
C Tong et al.
Mannan derived from fungal cell walls have potential uses as immunomodulating agents and vaccine adjuvants. Immunization with antigen conjugated to oxidized mannan (OM) or reduced mannan (RM) have induced differential immune responses in mi...
TLR-7 and -9 Stimulation of Peripheral Blood B Cells Indicate Altered TLR Signalling in Primary Sjögren's Syndrome Patients by Increased Secretion of Cytokines [0.03%]
原发性舍格伦综合征患者外周血B细胞的TLR-7和-9刺激导致细胞因子分泌增加，信号转导改变
M Karlsen,R Jonsson,J G Brun et al.
M Karlsen et al.
Primary Sjögren's syndrome (pSS) is a chronic, inflammatory autoimmune disease characterised by lymphocytic infiltrations in the exocrine glands, resulting in destruction of salivary and lacrimal glands. B cells have an important role in t...
CCL20-CCR6 Cytokine Network Facilitate Treg Activity in Advanced Grades and Metastatic Variants of Hepatocellular Carcinoma [0.03%]
CCL20-CCR6细胞因子网络促进高级别和转移性肝细胞癌中的Treg活性
W-M Li,H-R Liu
W-M Li
Tumour immunity regulates tumour restriction to the site of occurrence. Failure of this balance facilitates tumour spread beyond the primary organ of origin. Tregs are known to be recruited in infections, including viral infections like hep...