Computational Prediction of Usutu Virus E Protein B Cell and T Cell Epitopes for Potential Vaccine Development [0.03%]
乌苏土病毒E蛋白的BC和T细胞表位的计算预测及其潜在疫苗应用研究
N Palanisamy,J Lennerstrand
N Palanisamy
Usutu virus (family Flaviviridae), once confined to Africa, has emerged in Europe a decade ago. The virus has been spreading throughout Europe at a greater pace mostly affecting avian species. While most bird species remain asymptomatic car...
Siglec-9 is upregulated in rheumatoid arthritis and suppresses collagen-induced arthritis through reciprocal regulation of Th17-/Treg-cell differentiation [0.03%]
Siglec-9在类风湿关节炎中上调并通过互反调节Th17/Tregs细胞分化抑制胶原诱导的关节炎
X Wang,D Liu,Y Ning et al.
X Wang et al.
Sialic acid-binding Ig-like lectin-9 (Siglec-9) is a novel sialic acid-binding member of the immunoglobulin superfamily and is broadly expressed on immune cells, which can inhibit both innate and adaptive immune responses through immunorece...
Evaluation of Oxidative Stress and Antioxidant Status in Chronic Obstructive Pulmonary Disease [0.03%]
慢性阻塞性肺病患者氧化应激与抗氧化状态的评估
S Singh,S K Verma,S Kumar et al.
S Singh et al.
Chronic obstructive pulmonary disease (COPD) is a common respiratory condition involving the airways and characterized by airflow limitation. Gaseous and noxious particles play an important role in this process. Antioxidants are the substan...
Immune Class Regulation and Its Medical Significance Part II of a Report of a Workshop on Foundational Concepts of Immune Regulation [0.03%]
免疫分类调节及其医学意义——免疫调节基础概念研讨会报告第二部分
P A Bretscher,A Corthay,C C Anderson et al.
P A Bretscher et al.
We discussed different proposals for how the nature of the Th1/Th2 phenotype of an immune response is determined, and favoured one, the Threshold Hypothesis, as plausible and so useful as the basis for further discussions. The activation of...
Targets and Mechanisms in Prevention of Parkinson's Disease through Immunomodulatory Treatments [0.03%]
免疫调节治疗在帕金森病预防中的作用靶点和机制
M von Euler Chelpin,T Vorup-Jensen
M von Euler Chelpin
Parkinson's disease (PD) is the second most common neurodegenerative disease in the world; however, there is no cure for it. Current treatments only relieve some of the symptoms, without ceasing the disease, and lose efficacy with prolonged...
CD137 is a Useful Marker for Identifying CD4+ T Cell Responses to Mycobacterium tuberculosis [0.03%]
CD137是鉴定针对结核杆菌的CD4⁺T细胞反应的一个有用的标记
Z-H Yan,X-F Zheng,L Yi et al.
Z-H Yan et al.
Upregulation of CD137 on recently activated CD8+ T cells has been used to identify rare viral and tumour antigen-specific T cells from the peripheral blood. We aimed to evaluate the accuracy of CD137 for identifying Mycobacterium tuberculos...
IgM is Unable to Enhance Antibody Responses in Mice Lacking C1q or C3 [0.03%]
缺乏C1q或C3的小鼠中IgM不能增强抗体的应答反应
A Sörman,A Westin,B Heyman
A Sörman
A Commentary on a Workshop 'To Reveal the Foundational Concepts of Immune Regulation' (i.e. Tolerance) [0.03%]
对题为“揭示免疫调节的基本概念（即耐受性）”研讨会的评论
M Cohn
M Cohn
A summary of the workshop with its laudatory goal 'to reveal the foundational concepts in immunology' was recently published in SJI with an invitation to outsiders to comment. In the end, a foundational concept is one upon which we can all ...
Bacterial N-formyl Peptides Reduce PMA- and Escherichia coli-Induced Neutrophil Respiratory Burst in Term Neonates and Adults [0.03%]
细菌N-甲酰肽可减少早产儿及成人中由佛波酯和大肠杆菌诱导的中性粒细胞的呼吸爆发反应
M E Stålhammar,L Douhan Håkansson,R Sindelar
M E Stålhammar
Neutrophil migration and respiratory burst are the prerequisite for efficient first line defense against invading microorganisms. However, migration and respiratory burst can be compromised in adults and especially in newborn infants, where...
Proteomic Profiling Analysis Reveals a Link between Experimental Autoimmune Uveitis and Complement Activation in Rats [0.03%]
蛋白组学分析揭示了实验性自身免疫性葡萄膜炎与补体激活的关联性
D D Guo,B Hu,H Y Tang et al.
D D Guo et al.
Uveitis is an autoimmune disease that usually damages the vision function, leading to poor visual quality in patients. As an autoimmune ocular inflammatory disease, the pathogenesis of uveitis is associated with abnormal expression of some ...