CD20-Specific Immunoligands Engaging NKG2D Enhance γδ T Cell-Mediated Lysis of Lymphoma Cells [0.03%]
靶向CD20的免疫毒素结合NKG2D增强γδT细胞介导的淋巴瘤细胞溶解作用
M Peipp,D Wesch,H-H Oberg et al.
M Peipp et al.
Human γδ T cells are innate-like T cells which are able to kill a broad range of tumour cells and thus may have potential for cancer immunotherapy. The activating receptor natural killer group 2 member D (NKG2D) plays a key role in regula...
LPS-Induced ex vivo Cytokine Production is Not Augmented in Patients with Von Hippel-Lindau Disease [0.03%]
von Hippel-Lindau病患者的LPS诱导的细胞因子生成未被增强
D Kiers,H J L M Timmers,J Gerretsen et al.
D Kiers et al.
A Grenda,P Krawczyk
A Grenda
Lung cancer (LC) is the most common cause of cancer death in the world. A great challenge in treating NSCLC is the discovery of advanced, molecular tools to diagnose the disease in early stages as well as the development of immunotherapy. M...
Specific and Cross-reactive Plasmablast Response in Humans after Primary and Secondary Immunization with Vi Capsular Polysaccharide Typhoid Vaccine [0.03%]
新型霍乱疫苗诱导的免疫反应及其与经典口服 killed 霍乱弧菌疫苗的比较研究
S H Pakkanen,J M Kantele,L Rombo et al.
S H Pakkanen et al.
Secondary immunization with polysaccharide vaccines may imply a risk of hyporesponsiveness. Despite the wide use of typhoid Vi capsular polysaccharide vaccine, its potential tendency to hyporesponsiveness has been inadequately addressed. Wh...
M Cohn
M Cohn
In 2001, long ago by modern standards, Matzinger changed the emphasis of her Danger theory from one that downplayed the self-non-self discrimination to one that concerned itself with the regulation of effector class. This gave her theory a ...
Complement C5a-Induced Changes in Neutrophil Morphology During Inflammation [0.03%]
补体C5a诱导的炎症过程中中性粒细胞形态变化
S Denk,R P Taylor,R Wiegner et al.
S Denk et al.
The complement and neutrophil defence systems, as major components of innate immunity, are activated during inflammation and infection. For neutrophil migration to the inflamed region, we hypothesized that the complement activation product ...
The Abl-1 Kinase is Dispensable for NK Cell Inhibitory Signalling and is not Involved in Murine NK Cell Education [0.03%]
Abl-1激酶对于NK细胞抑制性信号转导是多余的，并且在小鼠NK细胞教育中不起作用
S Ganesan,T T Luu,B J Chambers et al.
S Ganesan et al.
Natural killer (NK) cell responsiveness in the mouse is determined in an education process guided by inhibitory Ly49 and NKG2A receptors binding to MHC class I molecules. It has been proposed that inhibitory signalling in human NK cells inv...
Assays for Infliximab Drug Levels and Antibodies: A Matter of Scales and Categories [0.03%]
英夫利昔单抗药物浓度和抗体检测：标尺与分类问题
L I Bader,S M Solberg,S H Kaada et al.
L I Bader et al.
Immunogenicity is a frequent cause of secondary non-response to tumour necrosis factor (TNF) inhibitors. Drug level measurement and detection of antidrug antibodies have been shown to be cost effective and clinically relevant, and a large n...
Comparative Study
Scandinavian journal of immunology. 2017 Sep;86(3):165-170. DOI:10.1111/sji.12572 2017
Anti-FcγRIIB (CD32) Antibodies Differentially Modulate Murine FVIII-Specific Recall Response in vitro [0.03%]
抗FcγRIIB（CD32）抗体通过不同机制调节小鼠FVIII特异性记忆B细胞的体外活化响应
N Vollack,J Friese,S Bergmann et al.
N Vollack et al.
Fc gamma receptors (FcγRs) for IgG regulate adaptive immune responses by modulating activating and inhibitory signalling pathways within immune cells. Data from a haemophilia A mouse model demonstrate that genetic deletion or blockade of t...
R K Tiwari
R K Tiwari