Platelet-Activating Factor Promotes Neutrophil Activation and Platelet-Neutrophil Complex Formation [0.03%]
血小板活化因子促进中性粒细胞活化及血小板-中性粒细胞复合物的形成
Lisa Wohlgemuth,Christiane Leonie Knapp,Laura Vidoni et al.
Lisa Wohlgemuth et al.
Controlling excessive inflammation remains an unmet clinical need, for example, during sepsis or after severe injuries. Platelet-activating factor (PAF) is central in thromboinflammatory processes. However, its role in the interaction of pl...
Redefining the Immunobiology of Organ Transplantation for New Clinical Horizons [0.03%]
重塑器官移植免疫生物学开拓临床新方向
Masoud H Manjili
Masoud H Manjili
Traditional organ transplantation relies on the Self-Non-self (SNS) model of immunity, focusing on donor-recipient compatibility and aggressive immunosuppression to prevent acute rejection. Although effective early, this strategy does not p...
Exploratory Study of CD10low Polymorphonuclear Leukocytes Preceding and Correlating With Postsurgical Inflammation [0.03%]
一项关于术前和术后炎症相关CD10low中性粒细胞的探索研究
Timo Michael Westermann,Joe Sendas,Alexander Sebastian Koller et al.
Timo Michael Westermann et al.
The lack of diagnostic and monitoring tools for postsurgical immunological complications such as systemic inflammation can contribute to a poor outcome despite modern intensive care. The need for reliable immune monitoring has been emphasis...
Well-Controlled Mucosal Exudation of Undiluted Plasma Proteins Serves Innate and Adaptive Immunity [0.03%]
未经稀释的血浆蛋白受控黏膜渗出对固有免疫和适应性免疫的作用
Carl Persson
Carl Persson
Distinct from the pulmonary circulation, the human respiratory mucosa is supplied by highly responsive, superficial, systemic microcirculations. In the early symptomatic phase of mucosal infections, circulating peptides-proteins of all size...
TCF3 and ID3 Regulate TSPAN32 Expression in Burkitt Lymphoma [0.03%]
TCF3和ID3调节Burkitt淋巴瘤中的TSPAN32表达
Grazia Scuderi,Katia Mangano,Gian Marco Leone et al.
Grazia Scuderi et al.
Burkitt lymphoma (BL) is an aggressive non-Hodgkin B-cell lymphoma characterised by chromosomal translocations involving the MYC gene, leading to its overexpression and driving uncontrolled proliferation. BL is categorised into endemic, spo...
Sona Mardanyan,Luiza Karapetyan,Alvard Antonyan
Sona Mardanyan
Adenosine (Ado) is an important purine that regulates numerous physiological functions. Adenosine deaminase (ADA) catalyses the irreversible deamination of Ado and its derivatives. Ado and ADA are the essential players in the immune system,...
Evaluating IL1RA-Autoantibodies Across SARS-CoV-2-Related Diseases [0.03%]
评估IL1RA自身抗体在与SARS-CoV-2相关疾病中的作用
Anish Behere,Pär Hallberg,Axel Cederholm et al.
Anish Behere et al.
Impact of Obesity on Treatment Response in Patients With Chronic Inflammatory Disease Receiving Biologic Therapy: Secondary Analysis of the Prospective Multicentre BELIEVE Cohort Study [0.03%]
肥胖对接受生物制剂治疗的慢性炎症性疾病患者疗效影响的二次分析——前瞻性多中心BELIEVE队列研究
Klara Riber Eggers,Karen Mai Møllegaard,Laura Gregersen et al.
Klara Riber Eggers et al.
Biological therapy is used to treat chronic inflammatory diseases (CIDs); however, up to 50% of patients fail to achieve an adequate clinical response. This study aimed to access the impact of obesity on clinical treatment response in CID p...
Percentages of Effector Memory T Cells in Peripheral Blood Associated With Non-Infectious Comorbidities in Common Variable Immunodeficiency Disorders [0.03%]
常见变异性免疫缺陷病患者外周血效应记忆T细胞比例与非感染性合并症的关系研究
Jesús A Álvarez-Álvarez,Estefanía Vásquez-Echeverri,Isaura P Sánchez et al.
Jesús A Álvarez-Álvarez et al.
Common variable immunodeficiency disorders (CVID) are characterized by hypogammaglobulinemia and increased susceptibility to infections. However, non-infectious comorbidities (NICM) are also frequent manifestations of the disease. We search...
Enhancing Primary Immunodeficiency Diagnosis: Findings From Targeted Genetic Testing in a Turkish Cohort [0.03%]
土耳其队列靶向基因检测在原发性免疫缺陷诊断中的应用及发现
Çiğdem Aydoğmus,Sibel Kaplan Sarıkavak,Burcu Cil et al.
Çiğdem Aydoğmus et al.
Primary immunodeficiency disorders (PIDDs) comprise a heterogeneous group of genetic conditions characterised by recurrent infections, immune dysregulation and increased susceptibility to malignancies. While clinical evaluation remains esse...