Büşra Koçali,Deniz Çağdaş
Büşra Koçali
Allergic Diseases in Common Variable Immunodeficiency: A Prospective Cross-Sectional Study on Prevalence and Allergy Biomarkers of Clinical Phenotypes [0.03%]
常见变量免疫缺陷的过敏性疾病：临床表型过敏生物标志物的流行病学的前瞻性横断面研究
Maria Giovanna Danieli,Ilaria Claudi,Stefania Auria et al.
Maria Giovanna Danieli et al.
The link between allergic conditions and common variable immunodeficiency (CVID) is still unclear. Only a few studies suggest allergic diseases are more prevalent in CVID patients than in the general population, and the role of IgE remains ...
Organoids in Personalised Oncology: Advances and Clinical Translation Toward Precision Cancer Therapy [0.03%]
肿瘤器官芯片在精准癌症治疗中的应用：进展与临床转化
Shurong Hai,Xishun Zhou,Junbo Li et al.
Shurong Hai et al.
Cancer remains one of the most pressing global health challenges due to its high incidence and mortality. Intratumoral and intertumoral heterogeneity pose significant challenges to effective treatment, driving metastasis, recurrence, therap...
Tibor Bakacs,Colin C Anderson
Tibor Bakacs
Immune checkpoint inhibitors (ICIs) have reshaped cancer treatment, offering durable remissions for a minority of patients. Yet their success has come with a difficult trade-off: a large proportion of patients develop immune-related adverse...
IL40: A Newly Described Cytokine With Conflicting Measurements and Detection Variability-Are There Different Forms? [0.03%]
IL-40：一种新描述的细胞因子具有矛盾的测定和检测变异性的细胞因子-是否存在不同形式？
Nora Euler,Wenqi Huang,Peter Hemmingsson et al.
Nora Euler et al.
Interleukin-40 (IL40) is a recently described 27 kDa cytokine encoded by C17orf99, originally suggested to play a role in B-cell biology, but its function is largely unknown. However, elevated serum levels have been reported in rheumatic di...
The Enigma of CD1d-iNKT Axis in Leishmaniases: Current Insights Into Immune Regulation [0.03%]
宿主抗利什曼病免疫调节中的CD1d-iNKT轴之谜：最新研究进展
Syamdas Bandyopadhyay,Surya Prakash Pandey
Syamdas Bandyopadhyay
Leishmaniases caused by Leishmania parasites may be fatal if proper treatment is lacking. These protozoan parasites employ several strategies to control the host immune system. Among these, manipulation of the antigen presentation pathway i...
From Thymic Hypoplasia to Immune Reconstitution: An Immunological Review of DiGeorge Syndrome [0.03%]
从胸腺发育不全到免疫重建：DiGeorge 综合征的免疫学再评价
Alejandro Tarango-García,Hanadys Ale,Hannia Michelle Prieto-Nevárez et al.
Alejandro Tarango-García et al.
DiGeorge syndrome (DGS), also known as 22q11.2 deletion syndrome, is the most prevalent chromosomal microdeletion syndrome. It presents with a heterogeneous phenotype and diverse clinical manifestations, which may include, but are not limit...
Beyond the Scar: What Can a Persistent BCG Vaccine Reaction in Infants Tell Us in an Immunological Point of View? [0.03%]
结核苗反应与婴儿免疫功能关系探究
Gonca Keskindemirci,Ece Aslan,Esra Yücel et al.
Gonca Keskindemirci et al.
The aim of this study was to evaluate children who still have not yet developed scar at the BCG vaccination site 16 weeks after vaccine administration without any local and systemic adverse reactions. The files of all children who were born...
Immunogenicity, Safety and Immune Persistence of Sabin Strain Inactivated Poliovirus Vaccine: A Phase III Clinical Trial [0.03%]
脊灰减毒活疫苗株灭活疫苗免疫原性、安全性及其免疫持久性临床试验（Ⅲ期）
Teng Huang,Cong Wu,Zhifang Ying et al.
Teng Huang et al.
The phased transition from oral poliovirus vaccine (OPV) to full-course immunisation with inactivated poliovirus vaccine (IPV) is a critical strategy for the global eradication of poliomyelitis. A randomised, double-blind, multi-centre, act...
Combined Immunodeficiency Associated With MAP2K1 p.Tyr130His Variant in Cardiofaciocutaneous Syndrome: A Case Report With Literature-Based Phenotypic Comparison [0.03%]
基于文献的表型比较的卡托脸皮肤综合征相关MAP2K1 c.389A>G (p.Tyr130His)变异联合免疫缺陷症病例报告
Şefika İlknur Kökcü Karadağ,Aslı Berivan Topçak,Yelda Türkmenoğlu et al.
Şefika İlknur Kökcü Karadağ et al.
Cardiofaciocutaneous syndrome (CFCS) is a RASopathy involving craniofacial, cardiac, cutaneous, and neurologic features. MAP2K1 mutations, particularly in the kinase domain, are linked to CFCS type 3. Immune dysfunction has not previously b...