IgE sensitization profiles to food, inhalant and insect venom in Norwegian blood donors and their impact on blood transfusions [0.03%]
挪威献血者对食物、吸入性过敏原和昆虫毒液的IgE敏感模式及其对输血的影响
Faiza Mahmood,Geir Hetland,Mohammad Reza Mirlashari et al.
Faiza Mahmood et al.
Allergen-specific immunoglobulin-E (As-IgE) in blood donors (BD) can be transferred to transfusion recipients via plasma-containing blood components (PCBC) and sensitize recipient's mast cells. These cells can activate upon allergen exposur...
Association between peripheral activated naive and double negative 2 B-cell subsets and clinical parameters in lupus nephritis patients [0.03%]
狼疮性肾炎患者外周激活的初始B细胞和双阴性B2细胞与临床参数之间的关联分析
Kittikorn Wangriatisak,Charlotte de Vries,Ravi Kumar Sharma et al.
Kittikorn Wangriatisak et al.
Altered composition of B-cell compartments is a known feature in patients with systemic lupus erythematosus (SLE). However, deep characterisation of B-cell subsets and their relation to clinical manifestations and disease activity in patien...
Production of novel peptide-targeting antibodies for anti-Müllerian hormone receptor 2 and induction of cytotoxicity in ovarian cancer cells [0.03%]
针对抗穆勒管激素受体2的新型肽类导向抗体的产生及其在卵巢癌细胞中细胞毒性的诱导
Çağrı Şakalar,Büşra Kurt,Sedat Sezen et al.
Çağrı Şakalar et al.
Ovarian cancer is generally diagnosed at late stages. Monoclonal antibodies (MAbs) targeting antigens in ovarian cancer are used in the clinic. Anti-Müllerian hormone receptor type 2 (AMHR2) is a receptor highly expressed in ovarian cancer...
Adjuvant alum regulates the eIF2a-GATA3 axis in CD4+ T cells to influence allergen immunotherapy [0.03%]
铝佐剂通过调节CD4+T细胞的eIF2a-GATA3轴影响过敏免疫治疗
Yan Feng,Zhishou Zhang,Hui Huangfu et al.
Yan Feng et al.
Allergen-specific immunotherapy (AIT) is an aetiology-targeting therapy for allergic diseases. The therapeutic mechanism of AIT is not fully understood yet. Endoplasmic reticulum stress is associated with the pathogenesis of allergic disord...
Expression of STAT- and T-cell-related genes in women with first-line treatment of relapsing-remitting multiple sclerosis [0.03%]
与复发缓解型多发性硬化症女性一线治疗相关的STAT和T细胞相关基因表达
Ludmiła Szewczak,Maja Machcińska,Magdalena Kierasińska et al.
Ludmiła Szewczak et al.
Relapsing-remitting multiple sclerosis is associated with changes in Jak/STAT pathways in immune cells, but the influence of disease-modifying drugs on these pathways is poorly understood. The aim of this study was to evaluate the impact of...
From agammaglobulinemia to neutropenia: 'The TCF-3 has different clinical presentations' [0.03%]
从无丙球蛋白血症到中性粒细胞减少症：TCF-3的不同临床表现
Hulya Kose,Akcahan Akalin,Sara Sebnem Kilic
Hulya Kose
The clinical picture of the TCF3 deficiency may manifest differently from neutropenia to antibody production defects. © 2024 The Scandinavian Foundation...
Unravelling T-cell dynamics and immune responses in initial and recurrent uveitis [0.03%]
初发和复发性色素膜炎T细胞动态和免疫反应的解析研究项目
Zhiruo Wang,Yuanyuan Yang,Guochun Chen et al.
Zhiruo Wang et al.
This study aimed to identify novel serological targets and investigate immune responses in patients with non-infectious uveitis, focusing on differences between initial onset and recurrent episodes. Differential gene expression analysis, im...
Serum integrin accumulation during asthma exacerbation: The role of matrix metalloproteinases [0.03%]
哮喘急性发作时血清整合素的累积：基质金属蛋白酶的作用
Tellez-Jimenez Olivia,Trejo-Jasso Christian,Ramos-Ramirez Patricia et al.
Tellez-Jimenez Olivia et al.
The inflammation caused by asthma exacerbation can lead to permanent changes in the airways and loss of lung function. Integrins are membrane receptors that interact with components of the extracellular matrix and cell adhesion molecules. I...
IgA monoclonal gammopathies are accompanied by higher total TGF-β1 levels than IgG or IgM monoclonal gammopathies [0.03%]
IgA单克隆丙球病患者体内总TGF-β1水平高于IgG或IgM单克隆丙球病患者
Irina Maslovarić,Dejana Kosanović,Dragana Marković et al.
Irina Maslovarić et al.
The progression of monoclonal gammopathies is affected by a range of factors, including the microenvironment surrounding plasma cells. It is recognized that TGF-β1 plays a distinct role in stimulating IgA production. Hence, this study aims...
A sex-dependent algorithm including kappa free light chain for multiple sclerosis diagnosis [0.03%]
一种包括kappa自由轻链的性激素依赖算法用于诊断多发性硬化症
Julia Maroto-García,Minerva Mañez,Ana Martínez-Escribano et al.
Julia Maroto-García et al.
Multiple sclerosis (MS) diagnosis includes the presence of restricted oligoclonal bands (OCB) in cerebrospinal fluid (CSF), but it has several limitations, as it is an observer-dependent time-consuming technique and offers a dichotomous res...