CD1d-iNKT Axis in Infectious Diseases: Lessons Learned From the Past [0.03%]
传染病中的CD1d-iNKT轴:从过去的经验中学习
Priyajit Chatterjee,Shubhranil Brahma,Peter Cresswell et al.
Priyajit Chatterjee et al.
CD1d is an antigen-presenting molecule that presents lipid or glycolipid antigens to iNKT cells, a distinct subset of T lymphocytes characterised by their innate-like properties and restricted use of Vα, Jα and Vβ segments. The CD1d-iNKT...
Research Advances on Molecular Mechanisms of Complement Regulatory Factor Vitronectin-Mediated Immune Escape of Pathogens [0.03%]
病原体利用补体调节因子视黄醇结合蛋白介导免疫逃逸的分子机制研究进展
Tong Wei,Yujie Yan,Yuelin Li et al.
Tong Wei et al.
Vitronectin (Vn) is a complement regulatory component found in humans and a variety of animals. It can inhibit the formation of membrane attack complexes in the complement system. Studies have shown that a variety of pathogenic microorganis...
Autoantibodies as Potential Liquid Biopsy Biomarker in Detection of Pancreatic Cancer: A Diagnostic Test Accuracy Review and Meta-Analysis [0.03%]
自身抗体在胰腺癌诊断中的潜在液体活检生物标志物价值:系统综述和meta分析
Yuqi Liu,Yuyi Gao,Yangxue Wu et al.
Yuqi Liu et al.
Autoantibodies against tumour-associated antigens (TAA) are promising biomarkers for cancer diagnosis. This systematic review aims to evaluate the diagnostic values of tumour-associated autoantibodies (TAAbs) in patients with pancreatic can...
Anti-HBc Positivity After Intravenous Immunoglobulin in Bone Marrow Transplant Patients [0.03%]
骨髓移植患者静脉注射免疫球蛋白后的抗HBc阳性反应
Fahir Ozturk,Mehmet Sezgin Pepeler
Fahir Ozturk
Inflammasomes and Cardiovascular Disease: Linking Inflammation to Cardiovascular Pathophysiology [0.03%]
炎症小体与心血管病研究:连接炎症与心血管病理生理学之间的纽带
Mohamed J Saadh,Faris Anad Muhammad,Rafid Jihad Albadr et al.
Mohamed J Saadh et al.
Cardiovascular diseases (CVDs) remain a leading cause of global mortality, driven by risk factors such as dyslipidemia, hypertension and diabetes. Recent research has highlighted the critical role of inflammasomes, particularly the NLRP3 in...
Inflammatory Immune Markers Associated With Thyroid Peroxidase Autoantibodies in Children Diagnosed With Both Type 1 Diabetes and Celiac Disease [0.03%]
与1型糖尿病和乳糜泻儿童患者甲状腺过氧化物酶自身抗体相关的炎症免疫标志物
Emanuel Fryk,Andrea Tompa,Alexander Lind et al.
Emanuel Fryk et al.
Autoimmune thyroid disease (AITD) is associated with other autoimmune endocrine diseases such as type 1 diabetes (T1D) and celiac disease (CeD). Thyroid peroxidase autoantibodies (TPOA) are biomarkers of AITD but may also occur in patients ...
Longitudinal Immune Profiling in Autoimmune Polyendocrine Syndrome Type 1 [0.03%]
自身免疫性多内分泌综合征1型的纵向免疫学分析
Isil Kucuka,Dorsa Iraji,Sarah Braun et al.
Isil Kucuka et al.
Autoimmune polyendocrine syndrome Type-1 (APS-1) is a rare, but severe organ-specific autoimmune disease caused by mutations in the autoimmune regulator (AIRE) gene. Lack of AIRE causes autoreactive T cells to escape negative selection and ...
The Role of Epstein-Barr Virus Molecular Mimicry in Various Autoimmune Diseases [0.03%]
EB病毒分子模拟在各种自身免疫性疾病中的作用
Ayesha Munir,Sanaullah Khan,Aisha Saleem et al.
Ayesha Munir et al.
Rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and multiple sclerosis (MS) are complex autoimmune inflammatory diseases influenced by genetic, environmental and infectious agents like Epstein-Barr virus (EBV). EBV has been pr...
Salvianolic Acid A From Salvia miltiorrhiza Suppresses Endometrial Carcinoma Progression via CD40-AKT-NF-κB Pathway [0.03%]
丹参中的丹酚酸A通过CD40-AKT-NF-κB通路抑制子宫内膜癌进展
Chunhua Zhang,Qing Liu,Lei Bi et al.
Chunhua Zhang et al.
We aimed to investigate the effects of Salvianolic acid A (SA), an active ingredient of Salvia miltiorrhiza Bunge, on the proliferation, metastasis and CD40-AKT-NF-κB signalling pathway in endometrial carcinoma (EC). Human EC cell lines (I...
Aberrant Lower CD6 Expression on Peripheral B Cells Associated With Liver/Kidney Injury and Autoantibody Production of Systemic Lupus Erythematosus Patients [0.03%]
系统性红斑狼疮患者外周血B细胞CD6表达异常与肝/肾损伤及自身抗体产生相关
Yongjian Chen,Yang Mei,Chun Zou et al.
Yongjian Chen et al.
Systemic lupus erythematosus (SLE) is a multi-system autoimmune disease characterised by aberrant activation and differentiation of autoreactive T and B cells, as well as the overproduction of autoantibodies. CD6, a cell-surface glycoprotei...