Dyssynergic Defecation Is Associated With Small Intestinal Bacterial Overgrowth [0.03%]
排粪失协同与小肠细菌过度生长有关
John A Damianos,Ayah Matar,Houssam Halawi et al.
John A Damianos et al.
Background: Microbial overgrowth (MO) in the small intestine can cause gastrointestinal symptoms and may arise from stasis, such as dysmotility. Microtypes of MO include small intestinal bacterial overgrowth (SIBO) and in...
Racial and Ethnic Disparities in Pandemic-Onset Disorders of Gut-Brain Interaction: Results From a Nationwide Survey [0.03%]
大流行引发的肠脑相互作用障碍的种族和民族差异——一项全国性调查的结果
Yixin Yang,Brennan M R Spiegel,William D Chey et al.
Yixin Yang et al.
Background: During the COVID-19 pandemic, the prevalence of disorders of gut-brain interaction (DGBI) in the US increased. The pandemic also led to health inequities among racial and ethnic minorities. Here, we conducted ...
Looking Beyond Anxiety and Depression: Integrating Neurological Factors in Chronic Constipation [0.03%]
超越焦虑和抑郁看待慢性便秘：整合神经学因素
Christian Messina
Christian Messina
Response to "Looking Beyond Anxiety and Depression: Integrating Neurological Factors in Chronic Constipation" [0.03%]
对“超越焦虑和抑郁：在慢性便秘中整合神经学因素”的回应
Zhifeng Zhao
Zhifeng Zhao
Thank you for your insightful comments, which have expanded our research perspective from psychology to neural mechanisms. We agree that the core challenge of refractory constipation is closely related to neurological factors, and its essen...
Evaluation of a Modified London Protocol to Diagnose Defecation Disorders With High-Definition Anorectal Manometry [0.03%]
改良的伦敦协议在高分辨率肛直肠曼OMETRY检查中的价值评估
Christian Lambiase,Giuseppe Chiarioni,Francesco Rettura et al.
Christian Lambiase et al.
Background: Anorectal manometry (ARM) is useful to diagnose defecation disorders. The International Anorectal Physiology Working Group (IAPWG) introduced a standardized sequence of maneuvers into clinical practice to perf...
Validation of Padova Classification of Post-Fundoplication Outflow Obstruction on High-Resolution Manometry in an International Multi-Center Study [0.03%]
一项国际多中心研究验证帕多瓦高分辨率测压食管下端手术后流出障碍分类法
Francesca Forattini,Khanh Hoang Nicholas Le,Luca Provenzano et al.
Francesca Forattini et al.
Background: Dysphagia after laparoscopic Nissen fundoplication (LNF) is common and may be due to post-fundoplication outflow obstruction (PFOO) as defined by high-resolution manometry (HRM) using the Padova Classification...
A Decade of Change: National Trends in Management and Outcomes of Achalasia Hospitalizations in the United States [0.03%]
美国食管失弛缓症住院患者的十年变化：管理和预后的国家趋势
Ritik M Goyal,Anand Shah,Rohan Karkra et al.
Ritik M Goyal et al.
Background: Achalasia is a rare esophageal motility disorder managed through various interventions, including laparoscopic Heller myotomy (LHM), pneumatic dilation (PD), and, more recently, per-oral endoscopic myotomy (PO...
Measuring Integrated Relaxation Pressure Across the Lower Esophageal Sphincter Alone in a Hiatus Hernia Reduces Inconclusive Outflow Obstruction Diagnosis [0.03%]
单独测量横膈疝下的下食管括约肌综合松弛压可减少流出道梗阻的不确诊断
Darshan Parekh,Trevor A Davis,Benjamin D Rogers et al.
Darshan Parekh et al.
Background: Elevated integrated relaxation pressure (IRP) on high-resolution manometry (HRM) could signify outflow obstruction, but could be artifactually elevated in the presence of a hiatus hernia (HH). We hypothesized ...
Altered Sigmoid Mucosal Innervation and Mast Cell Proximity to Sensory Nerve Fibers Are Associated With Symptom Severity in Patients With Irritable Bowel Syndrome [0.03%]
左半结肠易激综合症患者黏膜神经和肥大细胞的活体研究：肠易激综合症症状严重程度的相关因素
Pu-Qing Yuan,Michael Nash,Tao Li et al.
Pu-Qing Yuan et al.
Background: Peripheral neuronal pathways contribute to the pathophysiology of irritable bowel syndrome (IBS). Aims: To use high-resolut...
Clinical Characteristics and Outcomes of Rome IV Diarrhea-Predominant Irritable Bowel Syndrome and Functional Diarrhea Prescribed With Ondansetron: A Real-World Study [0.03%]
利托那韦治疗腹泻型肠易激综合征和功能性腹泻的临床特征和结果：一项真实世界研究
Caterina Sbarigia,Christian Lambiase,Mohsin F Butt et al.
Caterina Sbarigia et al.
Background: 5-HT3 receptor antagonists, such as ondansetron, are effective in the management of irritable bowel syndrome-diarrhea predominant (IBS-D). However, real-world data and evidence exploring the response to ondans...