Comparative Transcriptomic Analysis of Human Macrophages During Mycobacterium avium Versus Mycobacterium tuberculosis Infection [0.03%]
人巨噬细胞感染鸟分枝杆菌复合体细菌后的转录组学分析
Gül Kilinç,Robin H G A van den Biggelaar,Tom H M Ottenhoff et al.
Gül Kilinç et al.
The treatment of Mycobacterium avium (Mav) infection, responsible for over 80% of nontuberculous mycobacterial pulmonary disease, remains challenging due to rising antibiotic resistance and unsatisfactory success rates. Hence, there is a ne...
Identification of Specific Virulence Factors of Pseudomonas Strains in the Biocontrol of the Potato Pest Tecia solanivora [0.03%]
识别假单胞菌菌株在马铃薯害虫Tecia solanivora 生物防治中的特异性毒力因子
Luisa Pantoja,Pilar Vesga,Ziv Arbeli et al.
Luisa Pantoja et al.
Tecia solanivora (The Guatemalan potato tuber moth) is a major potato pest, responsible for up to 20% of crop losses and a significant economic impact. Certain Pseudomonas exhibit insecticidal activity and produce virulence factors with cyt...
Bacterial Toxin Exploits Host Membrane Phospholipid as a Receptor for Binding, Entry, and Cytopathogenicity [0.03%]
细菌毒素利用宿主膜磷脂作为结合、进入和细胞毒性的受体
Alejandra M Kirkpatrick,Thirumalai R Kannan
Alejandra M Kirkpatrick
Mycoplasma pneumoniae is a leading cause of bacterial community-acquired pneumonia, responsible for severe respiratory and extrapulmonary diseases in children and adults. The Community Acquired Respiratory Distress Syndrome (CARDS) toxin is...
An Improved Description of the Small RNA Landscape of the Human Fungal Pathogen Aspergillus fumigatus [0.03%]
改进的人类真菌病原菌烟曲霉的小RNA图谱描述
Xiaoqing Pan,Abdulrahman A Kelani,Lukas Schrettenbrunner et al.
Xiaoqing Pan et al.
Aspergillus fumigatus is a ubiquitous filamentous fungus and dangerous human pathogen that produces a limited pool of small RNAs under standard laboratory conditions. To better understand the rules of small RNA production in A. fumigatus, w...
The BosR Is Back! [0.03%]
鲍斯氏菌素抗性蛋白又回来了！
D Scott Samuels,Meghan C Lybecker
D Scott Samuels
BosR is a novel nucleic acid-binding protein in the ferric uptake regulator (FUR) family that regulates gene expression in the Lyme disease spirochete Borrelia (Borreliella) burgdorferi. This issue of Molecular Microbiology contains a compr...
The Mannose Phosphotransferase System in Enterococcus lactis Is Essential for Gastrointestinal Colonization [0.03%]
明尼苏达乳链球菌中的半乳糖磷酸转移酶系统对于肠道定植是必须的
Linan Xu,Xiangpeng Yang,Xingshuai Li et al.
Linan Xu et al.
Enterococcus lactis, a recently established species that was previously classified as Enterococcus faecium clade B, is a common commensal in human and animal intestines. Unlike the opportunistic pathogen E. faecium , it is largely harmless ...
The FsrA-Mediated Iron-Sparing Response Regulates the Biosynthesis of the Epipeptide EPE in Bacillus subtilis [0.03%]
铁节约调控细菌芽孢杆菌中环肽EPE生物合成
Sarah Miercke,Rabea Ghandour,Kai Papenfort et al.
Sarah Miercke et al.
Under severe nutrient-limiting conditions, Bacillus subtilis is able to form highly resilient endospores for survival. However, to avoid this irreversible process, it employs an adaptive strategy termed cannibalism, a form of programmed cel...
The Dual Role of the 16mer Motif Within the 3' Untranslated Region of the Variant Surface Glycoprotein of Trypanosoma brucei [0.03%]
克氏锥虫变异性表面糖蛋白3'非翻译区中16核苷酸基序的双重作用
Majeed Bakari-Soale,Christopher Batram,Henriette Zimmermann et al.
Majeed Bakari-Soale et al.
The variant surface glycoprotein (VSG) of African trypanosomes is essential for the survival of bloodstream form parasites. These parasites undergo antigenic variation, an immune evasion strategy in which they periodically switch VSG expres...
DNA Binding by BosR Controls RpoS-Dependent and -Independent Gene Expression in Borrelia burgdorferi [0.03%]
BosR结合DNA调控Borrelia burgdorferi的RpoS依赖和非依赖基因表达
André A Grassmann,Melissa A McLain,Michael R Freeman et al.
André A Grassmann et al.
BosR, the sole member of the ferric uptake regulator (FUR) family in Borrelia burgdorferi, is essential for the spirochete's transcriptional adaptation to the mammalian host environment. Although best known for activating rpoS and establish...
When One Is Enough: The Only Gα Subunit Governs Encystation and Other Cellular Processes in Entamoeba invadens [0.03%]
当一个就足够：单个Gα亚基控制内孢子形成和其他细胞过程在侵袭性溶组织内阿米巴中的作用
Shilpa Sarkar,Tiasha Chakraborty,Sudip K Ghosh
Shilpa Sarkar
Gα, Gβ, and Gγ-the heterotrimeric G protein subunits transmit signals from G-protein coupled receptors (GPCRs) to downstream pathways. The causative agent of Amoebiasis, Entamoeba, has been presumed to contain a GPCR signaling pathway pl...