Chain-Length Regulation by WzzE Is Necessary for, but Genetically Separable From, Cyclic Enterobacterial Common Antigen Synthesis [0.03%]
WzzE调节链长对环状肠杆菌共同抗原合成是必需的，但可以遗传分离
Joseph F Carr,Yohannes H Rezenom,Jennifer S Rudolf et al.
Joseph F Carr et al.
Enterobacterial common antigen (ECA) is a conserved glycan that supports intrinsic antibiotic resistance in Enterobacterales. ECA exists in outer membrane diacylglycerol-phosphate- and lipopolysaccharide-linked forms, and a cyclic periplasm...
To Move or Not to Move: When and How Bacteria Suppress Flagellar Motility [0.03%]
迁移还是不迁移：细菌何时以及如何抑制鞭毛运动
Fatemeh Mohagegh,Jacob Scadden,Matthew A B Baker
Fatemeh Mohagegh
Bacterial motility enables cells to migrate toward favourable environments and initiate surface colonisation. While motility can be lost through passive processes, such as shearing of filament, it frequently occurs as a tightly regulated re...
Roles of PknB and CslA in Cell Wall Morphogenesis of Streptomyces [0.03%]
结核分枝杆菌PknB和CslA在细胞壁形态发生中的作用
Marta Derkacz,Andrew Watson,Akshada Gajbhiye et al.
Marta Derkacz et al.
The bacterial cell wall is essential for maintaining cellular integrity and defining the mode of growth, with different species adopting distinct strategies for cell wall synthesis and remodelling. Streptomyces are filamentous bacteria pred...
Zachery R Lonergan,Sarah L Weisflog,Matthew Scurria et al.
Zachery R Lonergan et al.
The radical nitric oxide (·NO) is short-lived but has imprinted itself on many aspects of physiology and disease. ·NO's rapid production and consumption, coupled with its intrinsic reactivity, drive its biological importance; thus, defini...
Protein STM3547 From Salmonella typhimurium Is a Phosphofructose Kinase B-Type Enzyme With Ribose Kinase Activity [0.03%]
大肠杆菌STM3547蛋白是一种具有核糖激酶活性的磷酸果糖激酶B类酶
Regan D McCormick,Aatif A Jabbar,Jorge C Escalante-Semerena
Regan D McCormick
The first step in the metabolic utilization of ribose is the phosphorylation of its 5' hydroxyl group. The enteropathogenic bacterium Salmonella enterica subsp. enterica sv. Typhimurium str. LT2 (hereafter S. Typhimurium) has two known enzy...
The Absence of E. coli Nucleoid-Associated Protein FIS at Low Temperature Leads to an Adaptation Response That Causes a Shift Towards Genome Compaction in Small Rods [0.03%]
低温下缺少大肠杆菌染色体相关蛋白FIS导致的适应性反应使小杆状菌株基因组趋于紧密化
Pamela G Jones
Pamela G Jones
In contrast to the rod shape at 37°C, the morphology of Escherichia coli cells at temperatures just above the minimum temperature of growth is small rods. A study was initiated to determine the requirement of nucleoid-associated protein FI...
Naturally Occurring CodY Variants Alter Ligand Binding, DNA Target Affinity, and Virulence in Clostridioides difficile [0.03%]
自然发生的CodY变异体可改变难辨梭菌底物结合、DNA靶点亲和力及毒力
Md Kamrul Hasan,Sourav Roy,Revathi Govind
Md Kamrul Hasan
Clostridioides difficile is an important nosocomial pathogen and is the major cause of antibiotic-associated diarrhea and colitis. CodY is a global transcriptional regulator that coordinates metabolism and virulence in Gram-positive pathoge...
Regulation of the Yersinia pseudotuberculosis Type III Secretion System by the CpxAR Two-Component System [0.03%]
CpxAR双组分系统调节耶尔森菌假结核型III型分泌系统
Karen Hug,Erin Mettert,Melissa Estrada Escobar et al.
Karen Hug et al.
The type III secretion system (T3SS) is a cell envelope-spanning injectisome found in many Gram-negative pathogens. Expression of the T3SS is controlled by extracellular signals such as cell envelope stress. The CpxAR two-component system n...
Mannosylinositol Phosphorylceramide Biosynthesis Is Required for Cell Surface Adaptation to Ethanol Stress in Saccharomyces cerevisiae [0.03%]
曼诺糖脂质磷酸神经酰胺生物合成是酵母适应乙醇胁迫所必需的
Saki Sugihara,Reo Susami,Ayano Koga et al.
Saki Sugihara et al.
Saccharomyces cerevisiae exhibits a remarkable ability to tolerate high concentrations of ethanol during fermentation, yet the molecular basis underlying this adaptive trait remains incompletely understood. Here, we identify the biosynthesi...
The Complexity of erm-Mediated Resistance: Structural and Functional Perspectives From β-Hemolytic Streptococci [0.03%]
基于链球菌的结构和功能视角下的erm介导耐药性的复杂性
Lillie M Powell,Rita Berisio,P Rocco LaSala et al.
Lillie M Powell et al.
Macrolide overuse and resulting resistance crippled the applicability of one of the most important and successful classes of antibiotics. The rising incidence of invasive infections caused by β-hemolytic group A and group B streptococci ha...